Results 91 to 100 of about 27,519 (222)

The Malaysian Society of Gastroenterology and Hepatology Consensus Statements on Prevention and Early Detection of Hepatocellular Carcinoma in Malaysia

Journal of Gastroenterology and Hepatology, Volume 41, Issue 9, Page 2639-2655, September 2026.
ABSTRACT Background Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer‐related deaths in Malaysia. Early detection increases the likelihood of curative treatment and improves survival. This consensus document aims to provide evidence‐based, locally relevant recommendations for the prevention and early detection of HCC.
Su Yin Lau, Victoria Sinq‐Ling Kok, Soek‐Siam Tan, Syuhada Dan Adnan, Wei‐Lin Ng, Ban‐Hong Ang, Nur Yazmin Yaacob, Yeong Yeh Lee, Senamjit Kaur, Rosmawati Mohamed, Ping‐Foo Wong, Lee‐Ling Lim, Mohana Letchumanan, Shireene Ratna Vethakkan, Nurain Mohd Noor, Siow‐Foon Tan, Tiong‐Lim Low, Lee‐Boon Kiew, Wah‐Kheong Chan   +18 more
wiley   +1 more source

Molecular pathogenesis of hereditary hemochromatosis [PDF]

, 2016
. Hereditary hemochromatosis (HH) is an inherited iron overload disorder characterized by normal iron-driven erythropoiesis and abnormal iron metabolism, leading to excess iron deposited in parenchymal cells of liver, heart, and endocrine glands ...
Abdullahi, Mohamud Abukar Haji, Jiang, Chunmeng, Liu, Jingqi, Pu, Chunwen, Lang, Lang, Qiao, Liang   +5 more
core   +1 more source

Pathophysiological consequences and benefits of HFE mutations: 20 years of research

Haematologica, 2017
Mutations in the HFE (hemochromatosis) gene cause hereditary hemochromatosis, an iron overload disorder that is hallmarked by excessive accumulation of iron in parenchymal organs. The HFE mutation p.Cys282Tyr is pathologically most relevant and occurs in
Ina Hollerer, André Bachmann, Martina U. Muckenthaler   +2 more
doaj   +1 more source

Homozygous p.M172K mutation of the TFR2 gene in an Italian family with type 3 hereditary hemochromatosis and early onset iron overload

Haematologica, 2006
The p.M172K TFR2 mutation was identified in two Italian siblings aged 32 and 40 years old with primary iron overload. The two patients showed a severe increase in serum iron indices.
S Majore, F Milano, F Binni, L Stuppia, A Cerrone, A Tafuri, C De Bernardo, G Palka, P Grammatico   +8 more
doaj  

An unfortunate case of acquired hemochromatosis: a case report review of the clinical presentation, diagnosis, management, and prognosis

, 2016
Anam Tariq,1 Kevin Westra,2 Arben Santo3 1Department of Internal Medicine, Pinnacle Health Internal Medicine, 2Department of Gastroenterology, Harrisburg Gastroenterology, Harrisburg, PA, 3Department of Pathology, Virginia College of Osteopathic Medicine-
Santo A, Tariq A, Westra K
core  

Dietary and Sentinel Factors Leading to Hemochromatosis

, 2019
Although hereditary hemochromatosis is associated with the mutation of genes involved in iron transport and metabolism, secondary hemochromatosis is due to external factors, such as intended or unintended iron overload, hemolysis-linked iron exposure or ...
Chang-Kyu Oh, Yuseok Moon
core   +1 more source

Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes

, 2005
Background & Aims: Juvenile hemochromatosis is a severe form of hereditary iron overload that has thus far been linked to pathogenic mutations of the gene coding for hemojuvelin (HJV), on chromosome 1, or, more rarely, that coding for hepcidin (HAMP), on
J. Henrion, P. Andreone, CORRADINI, Elena, GARUTI, Cinzia, F. Ferrara, H. Kulaksiz, PIETRANGELO, Antonello, CALEFFI, Angela, W. Stremmel   +8 more
core   +1 more source

Case report: A rare case of hereditary hemochromatosis caused by a mutation in the HAMP gene in Fuyang, China

Frontiers in Medicine
Hemochromatosis, also known as siderosis, is a disease caused by excessive iron deposition in human organs and tissues, resulting from iron metabolism disorders.
Jinling Wang, Jing Xu, Ning Jiang, Hui Liu, Fengcheng Li, Beibei Wang, Jin Wang, Ziyu Chu, Lin Tan, Shasha Li   +9 more
doaj   +1 more source

Hemochromatosis and alcoholic liver disease

, 2003
The close association of excessive alcohol consumption and clinical expression of hemochromatosis has been of widespread interest for many years. In most populations of northern European extraction, more than 90% of patients with overt hemochromatosis ...
Fletcher, Linda M., Powell, Lawrie W.
core   +1 more source

HEREDITARY HEMOCHROMATOSIS: A RARE DISEASE OR A DIFFICULT DIAGNOSIS FOR A GENERAL PRACTITIONER?

Медицина в Кузбассе
Hemochromatosis is a hereditary disease belonging to the group of storage diseases characterized by impaired iron metabolism with its pathological accumulation in vital organs, including the liver.
Александра Валерьевна Морозова, Ольга Александровна Морозова, Николай Андреевич Бичан   +2 more
doaj