Results 91 to 100 of about 25,688 (240)

Pathophysiological consequences and benefits of HFE mutations: 20 years of research

Haematologica, 2017
Mutations in the HFE (hemochromatosis) gene cause hereditary hemochromatosis, an iron overload disorder that is hallmarked by excessive accumulation of iron in parenchymal organs. The HFE mutation p.Cys282Tyr is pathologically most relevant and occurs in
Ina Hollerer, André Bachmann, Martina U. Muckenthaler   +2 more
doaj   +1 more source

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell, Allison Close, Guoli Zhou, Troy C. Quigg   +3 more
wiley   +1 more source

An unfortunate case of acquired hemochromatosis: a case report review of the clinical presentation, diagnosis, management, and prognosis

, 2016
Anam Tariq,1 Kevin Westra,2 Arben Santo3 1Department of Internal Medicine, Pinnacle Health Internal Medicine, 2Department of Gastroenterology, Harrisburg Gastroenterology, Harrisburg, PA, 3Department of Pathology, Virginia College of Osteopathic Medicine-
Santo A, Tariq A, Westra K
core  

Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes

, 2005
Background & Aims: Juvenile hemochromatosis is a severe form of hereditary iron overload that has thus far been linked to pathogenic mutations of the gene coding for hemojuvelin (HJV), on chromosome 1, or, more rarely, that coding for hepcidin (HAMP), on
J. Henrion, P. Andreone, CORRADINI, Elena, GARUTI, Cinzia, F. Ferrara, H. Kulaksiz, PIETRANGELO, Antonello, CALEFFI, Angela, W. Stremmel   +8 more
core   +1 more source

Impacts of Salinity on Growth, Physiology and Tissue Integrity of Nile Tilapia: Implications for Coastal Aquaculture Under Climate Change

Aquaculture, Fish and Fisheries, Volume 6, Issue 3, June 2026.
ABSTRACT Climate change is responsible for salinity intrusion in coastal areas, which is significantly threatening the sustainability of aquaculture. This investigation focused on evaluating growth performance, proximate composition, blood morphology and histopathological modifications in Nile tilapia (Oreochromis niloticus) exposed to varying salinity
Shakil Ahmed, Md Abdullah Al Hadi, Md Ruhul Amin, Sarower Mahfuj, Md Sadiqul Islam, Md Shahjahan   +5 more
wiley   +1 more source

Screening for hemochromatosis in Turkey

, 2004
In this study we screened 3060 consecutive blood donors for an unbound iron-binding capacity level of
Gurel, S, Metin, O, Erkan, O, Bozkaya, H, Bozdayi, AM, Bektas, M, Yurdaydin, C, Akay, C, Aslan, O, Uzunalimoglu, O, Ibrahimoglu, D, Akbiyik, F, Dalva, K   +12 more
core   +2 more sources

Severe Lactic Acidosis in Decompensated Cirrhosis Despite Nondiagnostic Imaging

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Lactic acidosis is a strong predictor of mortality in cirrhosis, reflecting both impaired hepatic clearance and systemic tissue hypoxia. We describe a 38‐year‐old man with decompensated alcohol‐associated cirrhosis who developed severe lactic acidosis despite stable hemodynamics and initially nondiagnostic vascular imaging.
Nakul Ganju, Chibuzor Victor Nwachukwu, Juan Santiago‐Gonzalez, Shaharyar Naeem, Nicholas Azinge, Adeyinka O. Laiyemo   +5 more
wiley   +1 more source

Hemochromatosis and alcoholic liver disease

, 2003
The close association of excessive alcohol consumption and clinical expression of hemochromatosis has been of widespread interest for many years. In most populations of northern European extraction, more than 90% of patients with overt hemochromatosis ...
Fletcher, Linda M., Powell, Lawrie W.
core   +1 more source

Homozygous TFR2 (c.2093_2096del) Mutation in an Asymptomatic Patient With Type 3 Hereditary Hemochromatosis, First Report From Saudi Arabia

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Hereditary hemochromatosis (HH) is an inherited disorder of iron metabolism characterized by progressive iron accumulation in multiple organs. While most cases are associated with HFE mutations, non‐HFE variants such as mutations in the transferrin receptor‐2 (TFR2) gene represent rare causes of iron overload.
Omar M. Raslan, Dana S. Alamoudi
wiley   +1 more source

Hemochromatosis Treatment by Venipuncture Through History: Applying Venipuncture in the Treatment of Hemochromatosis

Southeastern European Medical Journal, 2018
Hemochromatosis is a hereditary disease caused by the mutation of genes responsible for regulating iron metabolism in the body. The mutation results in elevated iron absorption from the food that is deposited and stored in various organs and tissues. Due
Marija Čuljak
doaj   +1 more source