Results 111 to 120 of about 25,688 (240)

Quantitative T2* Magnetic Resonance Imaging for Iron Detection in Soft Tissue of the Fingers

NMR in Biomedicine, Volume 39, Issue 6, June 2026.
T2* MRI was evaluated for detecting iron in soft tissues of the fingers. After visual inspection of dual‐colored maps, multiple regions of interest were placed in the soft tissues at areas that indicated increased susceptibility. Lower T2* values, indicative of iron deposition, were detected in patients with microvasculopathy (right panel) but not in ...
Artemis Galani, Nikolaos I. Vlachogiannis, Vassilis Koutoulidis, Georgia Lymperopoulou, Petros P. Sfikakis, Thomas G. Maris, Lia Angela Moulopoulos   +6 more
wiley   +1 more source

Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang, Yizhi Ge, Hongguang Xiang, Ji Liu, Yu Tian, Yan Shen, Dan Zong   +6 more
wiley   +1 more source

Rare types of genetic hemochromatosis

, 2009
Most types of genetic hemochromatosis are due to mutations in the HFE gene, although similar iron overload and organ damage can also result from mutations in genes other than HFE in rare types of hemochromatosis. Non-HFE hemochromatoses have been divided
C. Camschella, E. Poggiali
core   +1 more source

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 12, Page 1673-1684, June 2026.
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo, Sepideh Mehravar, Ellen Choi, Ju Dong Yang, Hyun‐Seok Kim, Yun Wang, Aarshi Vipani, Hirsh D. Trivedi, Walid Ayoub, Parnian Naji, Alexander Kuo, Chun‐Ying Wu, Lorenzo Leggio, Juan Pablo Arab   +13 more
wiley   +1 more source

Hemochromatosis and blood donation

, 2017
The voluntary, unpaid, altruistic blood donor is a cornerstone of current transfusion medicine. The complexity of medical and ethical issues related to blood donation and hemochromatosis has led to a large number of studies related to the safety of the ...
Braseth, Turid Aarhus, Hervig, Tor, Røsvik, Anne Synnøve   +2 more
core  

The oral ferroportin inhibitor vamifeport prevents liver iron overload in a mouse model of hemochromatosis

HemaSphere
Hemochromatosis is an inherited iron overload condition caused by mutations that reduce the levels of the iron‐regulatory hormone hepcidin or its binding to ferroportin.
Naja Nyffenegger, Anna Flace, Ahmet Varol, Patrick Altermatt, Cédric Doucerain, Hanna Sundstrom, Franz Dürrenberger, Vania Manolova   +7 more
doaj   +1 more source

Deferoxamine Improves Radiation‐Induced Peripheral Neuropathy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Radiation‐induced peripheral neuropathy (RIPN) is a devastating sequela of radiation therapy (XRT). Current treatment options are limited. Deferoxamine (DFO) has been useful in treating radiation‐induced dermal fibrosis. This study aimed to evaluate DFO for RIPN. Thus, 18 mice received 30Gy of fractionated XRT.
Christopher V. Lavin, Alexander Z. Fazilat, Carter B. Kendig, Palca Shibale, Kelly X. Huang, Sriya Nemani, Jennifer B. Parker, Caleb Valencia, Naga A. R. Ailury, Michelle Griffin, Arash Momeni, Michael T. Longaker, Derrick C. Wan   +12 more
wiley   +1 more source

Hepatitis B Surface Antigen Loss and Improved Clinical Outcomes in US Individuals With Chronic Hepatitis B Virus Infection

Journal of Viral Hepatitis, Volume 33, Issue 6, June 2026.
ABSTRACT Hepatitis B surface antigen (HBsAg) loss is associated with improved clinical outcomes in patients with chronic hepatitis B virus (HBV) infection based on studies predominantly in Asian populations. We assessed real‐world associations between HBsAg loss and long‐term clinical outcomes in a diverse US population with chronic HBV infection. This
Myriam Drysdale, Rose Chang, Shuang Wang, Anna Coutinho, Vera Gielen, Theo Man, Rui Song, Mei Sheng Duh, Mandana Khalili, Dickens Theodore   +9 more
wiley   +1 more source

Arthropathy in juvenile hemochromatosis

, 2003
Objective. To evaluate whether arthropathy is associated with juvenile hemochromatosis and, if so, to assess the relationship between this feature and other clinical features of the disease. Methods.
Papanikolaou, G, Jibreel, I, Vaiopoulos, G, Politou, M, Sakellaropoulos, N, Loukopoulos, D   +5 more
core  

Non-HFE hemochromatosis: Pathophysiological and diagnostic aspects.

, 2013
International audienceRare genetic iron overload diseases are an evolving field due to major advances in genetics and molecular biology. Genetic iron overload has long been confined to the classical type 1 hemochromatosis related to the HFE C282Y ...
Beaumont-Epinette, Marie-Pascale, Brissot, Pierre, Jouanolle, Anne-Marie, Bardou-Jacquet, Edouard, Loréal, Olivier, Ben Ali, Zeineb   +5 more
core   +1 more source