Results 11 to 20 of about 23,592 (205)

Protein Diversity and Immune Specificity of Hemocyanin From Shrimp Litopenaeus vannamei

open access: yesFrontiers in Immunology, 2021
Hemocyanin is an important non-specific innate immune defense molecule with phenoloxidase, antiviral, antibacterial, hemolytic, and antitumor activities.
Xianliang Zhao   +9 more
doaj   +2 more sources

Hemocyanin of the caenogastropod Pomacea canaliculata exhibits evolutionary differences among gastropod clades.

open access: yesPLoS ONE, 2020
Structural knowledge of gastropod hemocyanins is scarce. To better understand their evolution and diversity we studied the hemocyanin of a caenogastropod, Pomacea canaliculata (PcH).
Ignacio Rafael Chiumiento   +5 more
doaj   +2 more sources

TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals

open access: yesFrontiers in Immunology, 2019
Mollusk hemocyanins have biomedical uses as carriers/adjuvants and nonspecific immunostimulants with beneficial clinical outcomes by triggering the production of proinflammatory cytokines in antigen-presenting cells (APCs) and driving immune responses ...
José M. Jiménez   +13 more
doaj   +2 more sources

The Microbial Composition of Penaeid Shrimps’ Hepatopancreas Is Modulated by Hemocyanin

open access: yesJournal of Immunology, 2021
Aquatic organisms have to produce proteins or factors that help maintain a stable relationship with microbiota and prevent colonization by pathogenic microorganisms.
Zhihong Zheng   +7 more
semanticscholar   +1 more source

Inter-Subunit Dynamics Controls Tunnel Formation During the Oxygenation Process in Hemocyanin Hexamers

open access: yesFrontiers in Molecular Biosciences, 2021
Hemocyanin from horseshoe crab in its active form is a homo-hexameric protein. It exists in open and closed conformations when transitioning between deoxygenated and oxygenated states.
Khair Bux   +6 more
doaj   +1 more source

Spatial Profiling of Germinal Centers in Mouse Secondary Lymphoid Organs Using MACSima Imaging Cyclic Staining Technology. [PDF]

open access: yesEur J Immunol
We developed a 50‐plex imaging protocol using the MACSima platform to characterize the microarchitecture of germinal centers in secondary lymphoid tissues. This workflow combines tissue processing, automated cyclic imaging, image preprocessing, and a new analysis method that detects morphological changes in irregularly shaped stromal cells.
Molina ISM   +4 more
europepmc   +2 more sources

Diversity, evolution, and function of myriapod hemocyanins

open access: yesBMC Evolutionary Biology, 2018
Background Hemocyanin transports O2 in the hemolymph of many arthropod species. Such respiratory proteins have long been considered unnecessary in Myriapoda. As a result, the presence of hemocyanin in Myriapoda has long been overlooked.
Samantha Scherbaum   +4 more
doaj   +1 more source

Short-Term Estivation and Hibernation Induce Changes in the Blood and Circulating Hemocytes of the Apple Snail Pomacea canaliculata

open access: yesMetabolites, 2023
States of natural dormancy include estivation and hibernation. Ampullariids are exemplary because they undergo estivation when deprived of water or hibernation when exposed to very low temperatures.
Cristian Rodriguez   +2 more
doaj   +1 more source

The diversity and evolution of chelicerate hemocyanins

open access: yesBMC Evolutionary Biology, 2012
Background Oxygen transport in the hemolymph of many arthropod species is facilitated by large copper-proteins referred to as hemocyanins. Arthropod hemocyanins are hexamers or oligomers of hexamers, which are characterized by a high O2 transport ...
Rehm Peter   +4 more
doaj   +1 more source

Molluscan Compounds Provide Drug Leads for the Treatment and Prevention of Respiratory Disease

open access: yesMarine Drugs, 2020
Respiratory diseases place an immense burden on global health and there is a compelling need for the discovery of new compounds for therapeutic development.
Kate Summer   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy