Results 41 to 50 of about 18,599 (219)

Hemocyanin-derived phenoloxidase activity: A contributing factor to hyperpigmentation in Nephrops norvegicus

, 2013
The phenomenon of hyperpigmentation (melanosis) in shellfish has long been attributed to phenoloxidase enzymes. Over the last number of years, the oxygen carrier hemocyanin, has demonstrated several immune- and physiological functionalities, most notably,
Coates, Christopher J., Nairn, Jacqueline, Coates, Christopher   +2 more
core   +1 more source

Preliminary Analysis of Hemocyanins in Hemolymph Plasma of Baikal Endemic Amphipods [PDF]

Journal of Stress Physiology & Biochemistry, 2016
Two-dimensional electrophoresis of plasma hemolymph proteins of several endemic Baikal amphipod species showed that, as expected, hemocyanin is the main major protein in plasma of these species.
D.S. Bedulina, A.N. Gurkov, B.K. Baduev, E.V. Borvinskaya, M.D. Dimova, M.A. Timofeyev   +5 more
doaj  

Effects of known phenoloxidase inhibitors on hemocyanin-derived phenoloxidase from Limulus polyphemus

, 2012
Inhibitors of phenoloxidase are used routinely to characterise the structural and functional properties of phenoloxidases. Hemocyanin-derived phenoloxidase activity is also sensitive to standard phenoloxidase inhibitors.
Clark, William McCaskill, Coates, Christopher J., Nairn, Jacqueline, Wright, Jamie, Coates, Christopher, Cairn, Jennifer A, Patterson, Alan, Cain, Jennifer A., Christopher Coates   +8 more
core   +1 more source

Hemocyanin Modification of Chitosan Scaffolds with Calcium Phosphate Phases Increase the Osteoblast/Osteoclast Activity Ratio—A Co-Culture Study

Molecules, 2020
The ongoing research on biomaterials that support bone regeneration led to the quest for materials or material modifications that can actively influence the activity or balance of bone tissue cells.
Benjamin Kruppke, Christiane Heinemann, Jana Farack, Simy Weil, Eliahu David Aflalo, Amir Sagi, Thomas Hanke   +6 more
doaj   +1 more source

Possible role of phosphatidylserine–hemocyanin interaction in the innate immune response of Limulus polyphemus

, 2011
Phenoloxidase enzymes and the associated pro-phenoloxidase activation cascade play an essential role in the immune response of arthropods. Phenoloxidase activity can be elicited in the oxygen carrier, hemocyanin, by the addition of the artificial inducer,
Jacqueline Nairn, Sharon M. Kelly, Coates, Christopher J., Kelly, Sharon M, Nairn, Jacqueline, Kelly, S.M., Coates, C.J., Coates, Christopher, Christopher J. Coates, Christopher Coates, Nairn, J., Kelly, Sharon M.   +11 more
core   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Entrapment of hemocyanin conformers as a tool for the definition of the structural model of cooperativity [PDF]

, 2013
Allostery has been established as a fundamental mechanism of regulation in most biological processes (Changeux, 2012). The most studied allosteric protein is hemoglobin, that has long been considered a paradigm for the investigation of allostery and ...
Minute, Fabrizio
core  

Response pattern of hemocyanin to Vibrio parahaemolyticus infection and its immune function in the swimming crab Portunus trituberculatus

Aquaculture Reports, 2023
Hemocyanin is a critical oxygen-transporting protein exhibiting multiple physiological functions, including protein storage and transportation, osmolarity regulation, molting, and immunomodulation in arthropods and mollusks.
Dongfang Sun, Yukun Li, Jianjian Lv, Junyang Guo, Ping Liu, Baoquan Gao   +5 more
doaj   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

Structure of arthropod hemocyanin

, 1986
Hemocyanins are large multi-subunit copper proteins that transport oxygen in many arthropods and molluscs. The amino acid sequence of subunit a of Panulirus interruptus hemocyanin (657 residues) has been completed and fitted to the electron-density map ...
Henk J. Bak, Jaap J. Beintema, Bak, Henk J., Soeter, N. M., Johan M. Vereijken, Soeter, Nell M., Vereijken, J. M., NEUTEBOOM, B, Neuteboom, Ben, Bak, H. J., Jekel, P. A., SOETER, NM, Neuteboom, B., Beintema, Jaap J., Ben Neuteboom, Nell M. Soeter, JEKEL, PA, Jekel, Peter A., Beintema, J. J., VEREIJKEN, JM, BAK, HJ, BEINTEMA, JJ, Peter A. Jekel, Vereijken, Johan M.   +23 more
core   +1 more source