Results 91 to 100 of about 268,961 (366)
Label‐Free Dual‐Modal Photoacoustic/Ultrasound Localization Imaging for Studying Acute Kidney Injury
Advanced Science, EarlyView.This work develops a 3D label‐free photoacoustic/super‐resolution ultrasound imaging system as a comprehensive non‐invasive tool for acute kidney injury (AKI) study. This technique visualizes the intricate structure of renal microvessels and provides critical physiological insights, including renal hemodynamics and oxygenation.
Shensheng Zhao +5 more
wiley +1 more source
Clinical Cardiology, Volume 45, Issue 12, Page 1255-1263, December 2022., 2022 Abstract Background The definitive treatment for chronic thromboembolic pulmonary hypertension (CTEPH) is pulmonary endarterectomy (PEA), which has good long‐term outcomes. However, after surgery, a quarter of the patients still have residual pulmonary hypertension (RPH). In pulmonary hemodynamics, there are no unified criteria for RPH, even though the
Wu Song +4 more
wiley +1 more source
Uncover Hidden Physical Information of Soft Matter by Observing Large Deformation
Advanced Science, EarlyView.Detecting internal abnormalities in soft matter remains challenging due to its heterogeneous nature. This study introduces a method that infers hidden physical properties by matching observed deformation with simulation through parallel Bayesian optimization.
Huanyu Yang +9 more
wiley +1 more source
Analysis of atherosclerotic plaque distribution in the carotid artery
Clinical Cardiology, Volume 45, Issue 12, Page 1272-1276, December 2022., 2022 Abstract Background The present study was designed to investigate the hypothesis that the outer wall at the carotid bifurcation is the most common area of atherosclerotic plaque deposition due to the low shear stress. Hypothesis We hypothesized that the most common site of arteriosclerosis in carotid arteries is different in the early and late stages ...
Shin‐Seok Yang +2 more
wiley +1 more source
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization
Advanced Science, EarlyView.This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan +12 more
wiley +1 more source
Predicting progression of aortic stenosis by measuring serum calcification propensity
Clinical Cardiology, Volume 45, Issue 12, Page 1297-1302, December 2022., 2022 Abstract Background The aim of this prospective, double‐blinded study in patients with aortic sclerosis was to determine whether a new calcification propensity measure in the serum could predict disease progression. Methods We included 129 consecutive patients with aortic sclerosis as assessed during a routine clinical echocardiographic exam. Clinical,
Reto Kurmann +4 more
wiley +1 more source
Dynamic Pathophysiological Insight into the Brain by NIR‐II Imaging
Advanced Science, EarlyView.The functional integration of benefits from small semiconducting dyes and biocompatible serum proteins ushered in a new frontier of deep wide‐field in vivo imaging technique, affording valuable pathophysiological insight into the functioning of neurovascular unit in space and time.
Si Chen +9 more
wiley +1 more source
Advanced Science, EarlyView.There is growing interest in understanding how classroom teaching works, but previous theories and studies leave a gap in the neurocognitive mechanisms involved in real classroom teaching. Here we show that during real classroom teaching, students' middle frontal cortex serves as a hub of a rapid cortical learning process, supporting their knowledge ...
Xiaodan Feng +6 more
wiley +1 more source
Longitudinal, Multimodal Tracking Reveals Lasting Neurovascular Impact of Individual Microinfarcts
Advanced Science, EarlyView.Jin et al. investigate the neurovascular impact of microinfarcts, revealing transient neural suppression with minimal cell death and recovery linked to vascular remodeling. Fast‐spiking interneurons exhibit reduced excitability, whereas regular‐spiking neurons showed increased bursting activity. Disruptions in low‐gamma phase locking suggest persistent
Yifu Jin +9 more
wiley +1 more source
Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1449-1455, December 2022., 2022 Abstract Objectives The extraction of a tooth exacerbates the stress in diabetic patients leading to diabetic complications so the aim was to evaluate the changes in blood cortisol, glucose, and oxygen saturation in type 2 diabetic patients during tooth extraction to pay special attention during a routine surgical procedure.
Zana Agani +6 more
wiley +1 more source