Results 91 to 100 of about 95,640 (249)
Percutaneous coronary intervention in coronary total occlusions: In which patients?
Mario Araya, Germán Armijo
doaj +1 more source
A titanium implant coating integrating berberine and copper‐doped strontium titanate leverages ultrasound to compromise bacterial membranes and induce cuproptosis‐like death. This approach resolves S. aureus infections in osteomyelitis models while suppressing inflammation and promoting osseointegration, demonstrating a dual‐functional strategy against
Guannan Zhang+8 more
wiley +1 more source
Macrophage Zc3h12c Limits Tissue Inflammation and Injury via Alternative Splicing of Pre‐mRNA
This work defines the context‐dependent function of Zc3h12c in macrophages using the Tnfrsf11a‐Cre system. It reveals Zc3h12c's dual mechanism—regulating RNA degradation and alternative splicing—with STAT1 as a key target. The findings elucidate a novel post‐transcriptional pathway and identify STAT1 isoforms as potential therapeutic targets for kidney
Chenyu Li+14 more
wiley +1 more source
CARDIAC AND CEREBRAL HEMODYNAMICS IN DRUG-INDUCED POSTURAL COLLAPSE [PDF]
Frank A. Finnerty+2 more
openalex +1 more source
Dynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes
Dynamic neural deactivation bridges traditionally distinct inhibitory mechanisms—direct inhibition and competition‐induced inhibition—revealing a common neural signature across modalities. Multimodal neuroimaging and behavioral experiments demonstrate a temporal dynamic characterized by progressive frontoparietal activation decay and enhanced sensory ...
Zhenhong He+6 more
wiley +1 more source
Stroke volume (SV) is a major indicator of cardiovascular function, providing essential information about heart performance and blood flow adequacy. Accurate SV measurement is particularly important for assessing patients with heart failure, managing ...
Vasiliki (Vicky) Bikia+11 more
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KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou+14 more
wiley +1 more source
A flexible piezoresistive pressure sensor with dual‐graded microstructures achieves both high sensitivity (69.8 kPa⁻¹) and a broad linear range up to 300 kPa (R2 = 0.997). Synergizing structural deformation and tunneling conduction, it enables rapid, stable, and accurate detection of subtle physiological signals, offering a scalable and cost‐effective ...
Ningning Bai+11 more
wiley +1 more source