Results 31 to 40 of about 398,944 (237)
Impact of Isovolemic Hemodilution-Red Cell Exchange on Health-Related Quality of Life in Patients With Sickle Cell Disease: A Pilot Study. [PDF]
J Clin ApherABSTRACT Sickle cell disease (SCD) negatively affects health‐related quality of life (HRQoL). Isovolemic hemodilution (IHD) red‐cell exchange (RCE) is being increasingly used to treat SCD‐related complications, but its impact on HRQoL has not been characterized.
Murray A +4 more
europepmc +2 more sources
Prevalence of Haemoglobine s in Araraquara-SP Population.
Revista Brasileira Multidisciplinar - ReBraM /Brazilian Multidisciplinay Journal, 2015 The Sickle Cell Anemia is a genetic hemoglobionopathy, characterized by an alteration in the hemoglobin molecule struture (HbA1), called hemoglobin S (HbS), which causes a distortion in the erythocytes structure, changing from spherical shape to sickle ...
Bruno Rocha de Jesus +4 more
doaj +1 more source
Revista Brasileira de Hematologia e Hemoterapia, 2014 Objective: The aim of the present study was to characterize sickle cell disease retinopathy in children and teenagers from Bahia, the state in northeastern Brazil with the highest incidence and prevalence of sickle cell disease.
Dayse Cury de Almeida Oliveira +5 more
doaj +1 more source
JCI Insight, 2018 The contribution of intracellular hemoglobin (Hb) oxidation to RBC-derived microparticle (MP) formation is poorly defined in sickle cell disease (SCD).
S. Jana +11 more
semanticscholar +1 more source
Sickle Retinopathy in a Person with Hemoglobin S/New York Disease
Case Reports in Genetics, 2012 A patient who presented with sickle retinopathy and hemoglobin electrophoresis results compatible with sickle cell trait was found, on further investigation, to be a compound heterozygote with hemoglobin S and hemoglobin New York disease.
Donovan Calder +4 more
doaj +1 more source
Acta Médica Portuguesa, 2017 Introduction: The benefits of manual versus automated red blood cell exchange have rarely been documented and studies in young sickle cell disease patients are scarce. We aim to describe and compare our experience in these two procedures.
Carlos Escobar +9 more
doaj +1 more source
Hemoglobin sickle cell disease in Brazil
Haematologica, 2013 We read with great interest the recent paper presented by Lionnet et al .[1][1] and we would like to briefly report our experience with hemoglobin SC (HbSC) disease.
A. C. Cabañas-Pedro +5 more
semanticscholar +1 more source
The post-mortem diagnosis of vasocclusive crisis in sickle cell disease
Autopsy and Case Reports, 2014 Sickle cell disease (SCD) comprises a group of genetic blood disorders that affect the hemoglobin molecular structure, and in some cases, the association with hemoglobin synthesis.
Varsha Bhatia +2 more
doaj +1 more source
Hemoglobin-Based Blood Substitutes and the Treatment of Sickle Cell Disease: More Harm than Help?
Biomolecules, 2017 Intense efforts have been made by both industry and academia over the last three decades to produce viable hemoglobin (Hb)-based oxygen carriers (HBOCs), also known as “blood substitutes”.
A. Alayash
semanticscholar +1 more source
Biologic and Clinical Efficacy of LentiGlobin for Sickle Cell Disease.
New England Journal of Medicine, 2021 BACKGROUND Sickle cell disease is characterized by the painful recurrence of vaso-occlusive events. Gene therapy with the use of LentiGlobin for sickle cell disease (bb1111; lovotibeglogene autotemcel) consists of autologous transplantation of ...
J. Kanter +18 more
semanticscholar +1 more source