Results 11 to 20 of about 204,109 (254)
Analysis of sickle hemoglobin [PDF]
Journal of Pathology of Nepal, 2013 Background: Sickle Hemoglobin is the most common pathological hemoglobin mutation worldwide which forms sickle shape or elongated forms on deoxygenation.
A Shrestha, S Karki
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Feasibility and utility of a sickle cell disease registry for research and patient management [PDF]
, 2009 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis aimed to evaluate the feasibility and utility of a sickle cell disease registry for clinical patient management and research.
Gilmore, Annette
core +7 more sources
Elastic property of sickle and normal hemoglobin protein: Molecular dynamics
AIP Advances, 2022 This work focuses on identifying the conformational stability and binding components in sickle and normal hemoglobin to explore the elastic properties and realize the stiffness by using molecular dynamics simulation. Our investigation shows that a larger
Jhulan Powrel, Narayan Prasad Adhikari
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Asymmetric sickle cell retinopathy in a patient with sickle cell hemoglobin D disease: A case report
Indian Journal of Ophthalmology. Case Reports, 2023 Sickle cell disease (SCD), the most commonly inherited hemoglobinopathy, can result in vision loss due to sickle cell retinopathy (SCR), vascular occlusions, and retinal atrophy.
Anil B Gangwe +5 more
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The Microrheology of Sickle Hemoglobin Gels [PDF]
Biophysical Journal, 2010 Sickle cell disease is a rheological disease, yet no quantitative rheological data exist on microscopic samples at physiological concentrations. We have developed a novel method for measuring the microrheology of sickle hemoglobin gels, based on magnetically driven compression of 5- to 8-microm-thick emulsions containing hemoglobin droplets ...
Zakharov, Mikhail N. +3 more
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Knowledge and Attitudes towards Sickle Cell Disease Screening: A Study of Members of the UK Sickle Cell Society [PDF]
, 2006 Over the past fifty years there has been an increase in the number of people in the UK who have a Sickle Cell Disorder (SCD) or are carriers. This increase has led to an expansion in research in this area; however one particular area that has not been ...
Millan, Jenny +2 more
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BMC Biology, 2023 Background Intracellular hemoglobin polymerization has been supposed to be the major determinant for the elevated rigidity/stiffness of sickle erythrocytes from sickle cell anemia (SCA) patients.
Kun Wang +5 more
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Nonideality and the Nucleation of Sickle Hemoglobin [PDF]
Biophysical Journal, 2000 The homogeneous and heterogeneous nucleation kinetics of sickle hemoglobin (HbS) have been studied for various degrees of solution crowding by substitution of cross-linked hemoglobin A, amounting to 50% of the total hemoglobin. By cross-linking hemoglobin A, hybrid formation between hemoglobin A and hemoglobin S was prevented, thus simplifying the ...
Ivanova, Maria +4 more
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Journal of Applied Hematology, 2022 BACKGROUND: Sickle cell disease and its variants result from an abnormal hemoglobin, hemoglobin S (HbS), caused by a single point mutation in the Beta-Globin gene.
Hareem Alam, Natasha Ali
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Thermal properties of normal and sickled hemoglobin protein
Bibechana, 2021 Thermodynamic properties of sickled and normal hemoglobin protein are considered within the framework of classical molecular dynamics. Here we have studied the specific heat capacity and RMSD (Root Mean Square Deviation) of both types of hemoglobin ...
Jhulan Powrel, Narayan P Adhikari
doaj +3 more sources