Results 21 to 30 of about 46,727 (267)

Prevalence of Haemoglobine s in Araraquara-SP Population.

open access: yesRevista Brasileira Multidisciplinar - ReBraM /Brazilian Multidisciplinay Journal, 2015
The Sickle Cell Anemia is a genetic hemoglobionopathy, characterized by an alteration in the hemoglobin molecule struture (HbA1), called hemoglobin S (HbS), which causes a distortion in the erythocytes structure, changing from spherical shape to sickle ...
Bruno Rocha de Jesus   +4 more
doaj   +1 more source

Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia [PDF]

open access: yes, 2017
Hydroxyurea treatment is recommended for children with sickle cell anemia (SCA) living in high-resource malaria-free regions, but its safety and efficacy in malaria-endemic sub-Saharan Africa, where the greatest sickle-cell burden exists, remain unknown.
Hodges, James S.   +8 more
core   +2 more sources

Feasibility Study of the “HemoTypeSC” Test for the Rapid Screening of Sickle Cell Disease in Côte D’Ivoire

open access: yesAdvances in Hematology, 2021
Sickle cell disease is a hereditary disease that predominantly affects black people. It is very widespread in sub-Saharan Africa, particularly at the Lehmann “sickle belt” level, where the prevalence of the hemoglobin S involves at least 10% of the ...
Jeannette Bassimbié Kakou Danho   +4 more
doaj   +1 more source

Hemorheological risk factors of acute chest syndrome and painful vaso-occlusive crisis in children with sickle cell disease

open access: yesHaematologica, 2012
Background Little is known about the effects of blood rheology on the occurrence of acute chest syndrome and painful vaso-occlusive crises in children with sickle cell anemia and hemoglobin SC disease.Design and Methods To address this issue, steady ...
Yann Lamarre   +13 more
doaj   +1 more source

Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2014
Objective: The aim of the present study was to characterize sickle cell disease retinopathy in children and teenagers from Bahia, the state in northeastern Brazil with the highest incidence and prevalence of sickle cell disease.
Dayse Cury de Almeida Oliveira   +5 more
doaj   +1 more source

Haemoglobinopathies and newborn haemoglobinopathy screening in Germany. [PDF]

open access: yes, 2009
Germany has been an immigration country since the early 1950s. In December 2007, 6.7 million non-German citizens lived in the country. However, the total number of citizens with a migration background is 15–20 million, about 9 million of whom come ...
Dickerhoff, R.   +2 more
core   +1 more source

THE STATE OF HEMOGLOBIN IN SICKLED ERYTHROCYTES [PDF]

open access: yesThe Journal of Experimental Medicine, 1966
Electron microscopic and other evidence have provided support for the hypothesis that the sickling phenomenon is due to the intracellular formation of long slender crystals of reduced sickle hemoglobin. The rapid growth of these crystals causing tenting of the cell membrane is responsible for the bizarre distortion of the erythrocytes and presumably ...
openaire   +2 more sources

Sickle Retinopathy in a Person with Hemoglobin S/New York Disease

open access: yesCase Reports in Genetics, 2012
A patient who presented with sickle retinopathy and hemoglobin electrophoresis results compatible with sickle cell trait was found, on further investigation, to be a compound heterozygote with hemoglobin S and hemoglobin New York disease.
Donovan Calder   +4 more
doaj   +1 more source

Partial Red Blood Cell Exchange in Children and Young Patients with Sickle Cell Disease: Manual Versus Automated Procedure

open access: yesActa Médica Portuguesa, 2017
Introduction: The benefits of manual versus automated red blood cell exchange have rarely been documented and studies in young sickle cell disease patients are scarce. We aim to describe and compare our experience in these two procedures.
Carlos Escobar   +9 more
doaj   +1 more source

Nutritional status of young children with inherited blood disorders in western Kenya. [PDF]

open access: yes, 2014
To determine the association between a range of inherited blood disorders and indicators of poor nutrition, we analyzed data from a population-based, cross-sectional survey of 882 children 6–35 months of age in western Kenya.
Ruth, LJ   +4 more
core   +1 more source

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