Results 191 to 200 of about 857,759 (309)

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Clinical and Immunological Factors Associated with Disease Activity in MPO-ANCA-Associated Vasculitis. [PDF]

Open Access Rheumatol
Chen Y, Shuai Z.
europepmc   +1 more source

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu, Jiaheng Lin, Yifei Zhu, Ying Liu, Guoren Zhou   +4 more
wiley   +1 more source

Comparative Effectiveness of Intravenous, Oral, and Topical Tranexamic Acid in Elective Spine Surgery: A Systematic Review and Network Meta-Analysis. [PDF]

Global Spine J
Hammadeh BM, Sabet CJ, Al-Qunbar A, Sabbah L, Mohammad AK, Hasan Z, Kikhia A, Al-Barbarawi MK.   +7 more
europepmc   +1 more source

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

Advanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer, Noël Strasser, Ilakkiya Ravindrarajah, Elsa Wrenger, Kristian Ivkovic, Jan Ševčík, Sima Šarčević, Lenka Červenková, Jáchym Rosendorf, Václav Liška, Alexandre H. Anthis, Thomas Rduch, Inge K. Herrmann   +12 more
wiley   +1 more source

Interventions following routine hemoglobin assessment after vaginal delivery. [PDF]

Pregnancy (Hoboken)
Fujiwara S, Siu A, Yamasato K.
europepmc   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Hemolytic Jaundice and Anemia With Methemoglobinemia in Dizygotic Newborn Twins With Hb Evans: Case Report.

Neonatology
Saldarriaga A, Zeiler BB, Brennan R, Bahr TM, Ohls RK, Gallagher PG, Christensen RD.   +6 more
europepmc   +1 more source

Development and validation of a low-cost, wearable near-infrared spectroscopy system for quantifying tissue water fraction in the human brain. [PDF]

J Biomed Opt
Wu KC, Renna M, Otic N, Starkweather Z, Kierul OS, Smith C, Franceschini MA, Robinson MB.   +7 more
europepmc   +1 more source

Green's Functions of Non‐Hermitian Systems at Exceptional Deficiency

Advanced Science, EarlyView.
We analyze the responses of a non‐Hermitian lattice system under the condition of exceptional deficiency (ED), when all bands in the system are formed by exceptional points. Using the frequency domain, we identify novel steady‐state responses that root in the broadband super‐Lorentzian Green's function (GF).
Congwei Lu, Guancong Ma
wiley   +1 more source