Results 51 to 60 of about 23,660,822 (374)

Pitfalls in estimation of glycosylated hemoglobin: A rare hemoglobin variant—Hb Hope

open access: yesJournal of Diabetology, 2021
Hemoglobin (Hb) Hope is a rare Hb variant which is clinically silent but causes spuriously high glycated hemoglobin (HbA1c). We report a case of a 45-year-old gentleman, planned for elective total hip replacement, who presented with very high HbA1c with ...
Anu Mathew   +2 more
doaj   +1 more source

Hereditary persistence of fetal hemoglobin: a study of 79 affected persons in 15 Negro families in Baltimore.

open access: yesBlood, 1963
Hereditary persistence of fetal hemoglobin is an anomaly of hemoglobin production apparently caused by a mutant gene that inhibits synthesis of hemoglobins A and A2.
C. Conley   +9 more
semanticscholar   +1 more source

Reactions of hemoglobin with phenylhydrazine: a review of selected aspects. [PDF]

open access: yes, 1985
It is well known that phenylhydrazine induces hemolytic anemia. This is thought to result from the reaction of phenylhydrazine with hemoglobin. The accompanying oxidation of phenylhydrazine leads to the formation of a number of products, including ...
Hill, HA, Shetlar, MD
core   +2 more sources

Effect of Stress Hyperglycemia on Neurological Deficit and Mortality in the Acute Ischemic Stroke People With and Without Diabetes

open access: yesFrontiers in Neurology, 2020
Objective: To determine the relationship between stress hyperglycemia and prognosis of acute ischemic stroke people with and without diabetes.Methods: A subgroup of 8,622 acute ischemic stroke people with baseline levels of fasting blood glucose and ...
Jiejie Li   +35 more
doaj   +1 more source

Relative affinity of hemoglobin S and hemoglobin A for carbon monoxide and oxygen.

open access: yesClinical Chemistry, 1974
The relative affinity constants of hemolysates from individuals with hemoglobins A, S, or AS have been measured at 37 and 26 ° C. Observed values of all hemoglobin types were the same at both temperatures, K 37 = 230, K 26 = 296.
F. Rodkey   +3 more
semanticscholar   +1 more source

The Steady-State Transport of Oxygen through Hemoglobin Solutions [PDF]

open access: yes, 1966
The steady-state transport of oxygen through hemoglobin solutions was studied to identify the mechanism of the diffusion augmentation observed at low oxygen tensions. A novel technique employing a platinum-silver oxygen electrode was developed to measure
Friedlander, S. K., Keller, K. H.
core   +2 more sources

S-C hemoglobin: a clinical study.

open access: yesBlood, 1961
are familiar with the chronically ill, eunuchoid appearance that typifies patients with sickle cell anemia. The subtleties in the clinical expression of hemoglobin S-C disease, however, offer a variety of pictures, sometimes even simulating life ...
G. River, A. Robbins, S. Schwartz
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Hemoglobin Subunit-Subunit Affinity-Determinant of Hemoglobin Formation [PDF]

open access: yes, 1989
Hemoglobin A₂ is often elevated in β-thalassemia and decreased in α-thalassemia. This might be due to hemoglobin subunit-subunit affinity variation. It has been inferred from the study of abnormal hemoglobins that the a subunits have higher affinity for ...
Carter, Inge R., Mansouri, Ali
core   +2 more sources

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