Results 71 to 80 of about 23,191 (234)

The wider perspective: Barriers and recommendations for transfusion support for patients with sickle cell disease in low‐ and middle‐income countries

British Journal of Haematology, EarlyView.
Globally, sickle cell disease (SCD) is the most common inherited haemoglobinopathy. The highest burden of SCD is encountered in low‐ and middle‐income countries (LMICs), most of which lack the resources to contend with the disease. Blood transfusion remains central to the emergent treatment and prevention of complications of SCD.
Jeremy W. Jacobs, Luiz Amorim, France Pirenne, Claude Tayou, Ijele Adimora, Lydia H. Pecker, Aaron A. R. Tobian, Jeannie Callum, Julie Makani, Mark T. Gladwin, Meghan Delaney, Darrell J. Triulzi, Isaac Odame, Evan M. Bloch   +13 more
wiley   +1 more source

P1508: LUSPATERCEPT REDUCES THE BURDEN OF RED BLOOD CELL TRANSFUSION IN PATIENTS WITH BETA -THALASSEMIA AND COMORBIDITIES: THE EXPERIENCE OF A SINGLE THALASSEMIA AND SICKLE CELL UNIT IN A UNIVERSITY HOSPITAL

HemaSphere, 2022
S. Delicou, M. Triantafyllou, A. Xydaki, C. Savvidis, K. Aggeli, I. Koskinas   +5 more
doaj   +1 more source

Underlying disease is the main risk factor in post‐splenectomy complication risk: Data from a national database

British Journal of Haematology, EarlyView.
The association between underlying haematological disease, age at splenectomy and post‐splenectomy complications was explored among 1348 splenectomized patients, followed in 53 clinical centres with a median follow‐up time of 13 years and affected by transfusion‐dependent thalassaemia (TDT), non‐transfusion‐dependent thalassaemia (NTDT), sickle cell ...
Maddalena Casale, Raffaella Colombatti, Manuela Balocco, Paola Corti, Susanna Barella, Giovanna Graziadei, Loredana Farinasso, Tommaso Mina, Simone Cesaro, Tommaso Casini, Fiorina Giona, Saverio Ladogana, Pellegrina Pugliese, Lucia Dora Notarangelo, Antonella Sau, Simone Ferrero, Giovanni Palazzi, Giovanna Russo, Ilaria Lazzareschi, Marilena Serra, Saveria Campisi, Gianluca Boscarol, Elena Facchini, Carlo Baronci, Maria Caterina Putti, Domenico Roberti, Marzia Manilia, Antonio Ivan Lazzarino, Gian Luca Forni, Silverio Perrotta, on behalf of the Italian Network of Asplenia, Piero Farruggia, Francesca Fioredda, Paola Giordano, Federico Verzegnassi, Maria Luisa Casciana, Assunta Tornesello, Ilaria Capolsini, Paolo Grotto, Paola Maria Grazia Sanna, Luciana Rigoli, Rosanna Di Concilio, Flavia Rivellini, Annamaria Pansanisi, Gloria Colarusso   +44 more
wiley   +1 more source

Is high pressure liquid chromatography an effective screening tool for characterization of molecular defects in hemoglobinopathies?

Indian Journal of Pathology and Microbiology, 2013
Introduction: Hemoglobinopathies constitute entities that are generated by either abnormal hemoglobin or thalassemias. high pressure liquid chromatography (HPLC) is one of the best methods for screening and detection of various hemoglobinopathies but it ...
Nikhil Moorchung, Joseph Phillip, Ravi Shankar Sarkar, Rupesh Prasad, Vibha Dutta   +4 more
doaj   +1 more source

Acute splenomegaly, haemolysis, and thrombocytopenia following luspatercept initiation in a patient with transfusion‐dependent thalassaemia: A case report

British Journal of Haematology, EarlyView.
Summary Patients with transfusion‐dependent thalassaemia (TDT) require chronic, life‐sustaining red blood cell transfusions, which contribute to iron overload and associated morbidity and mortality. Luspatercept, an inhibitor of the transforming growth factor‐beta pathway, decreases transfusion requirements in a subset of transfusion‐dependent β ...
Bianca Zaidel, Stephanie Garland, Hayley Merkeley   +2 more
wiley   +1 more source

Unveiling Extramedullary Hematopoiesis: A Case Report Highlighting the Causes, Symptoms, and Management Strategies

Thalassemia Reports
Extramedullary hematopoiesis (EMH) serves as a compensatory mechanism in chronic hemolytic anemias, such as thalassemia, and can result in spinal cord compression.
Konstantinos Manganas, Aikaterini Xydaki, Angeliki Kotsiafti, Olympia Papakonstantinou, Sophia Delicou   +4 more
doaj   +1 more source

Spectrum of hemoglobin variants in the population of northern region of West Bengal: An ethnogenetic proposition

Journal of Family Medicine and Primary Care, 2014
Context: The birth of transfusion-dependent states of hemoglobinopathies including thalassemias is preventable by population screening and genetic counseling.
Bidyut Krishna Goswami, Raghunath Pramanik, Sudipta Chakrabarty, Partha Pratim Pal, Sarama Banerjee, Arghya Bandyopadhyay   +5 more
doaj   +1 more source

HbA2 measurements in β-thalassemia and in other conditions

Thalassemia Reports, 2014
Quite a few papers have been written on the significance of elevated hemoglobin (Hb) A2 as a parameter for the diagnosis of β-thalassemia trait, on the cutoff values to be used in diagnostics and on the significance and effects of factors reducing or ...
Giovanni Ivaldi, Giuseppina Barberio, Cornelis L. Harteveld, Piero Giordano   +3 more
doaj   +1 more source

Prevalence of hemoglobinopathies in the Brazilian adult population: National Health Survey 2014-2015.

Revista brasileira de epidemiologia = Brazilian journal of epidemiology, 2019
OBJECTIVE To describe the prevalence of hemoglobinopathies in the Brazilian adult population, according to laboratory tests from the National Health Survey.
L. G. Rosenfeld, N. Bacal, Maria Alice Martins Cuder, Alanna Gomes da Silva, Í. Machado, C. A. Pereira, M. F. M. Souza, D. Malta   +7 more
semanticscholar   +1 more source

Glycated albumin and fructosamine do not improve accuracy of glycaemic control assessment in patients with conditions reported to affect HbA1c reliability

Diabetic Medicine, EarlyView.
Abstract Aims HbA1c testing in African populations may be limited due to high prevalence of hemoglobinopathies, anaemia, malaria and renal impairment. We aimed to assess the performance of glycated albumin (GA) and fructosamine in comparison to HbA1c for determining glycaemic control in Africans living with type 2 diabetes.
Anxious J. Niwaha, Priscilla A. Balungi, Timothy J. McDonald, Andrew T. Hattersley, Beverley M. Shields, Moffat J. Nyirenda, Angus G. Jones   +6 more
wiley   +1 more source