Results 91 to 100 of about 20,435 (244)
Artemisinin therapy for malaria in hemoglobinopathies: A systematic review
© The Author(s) 2018. Artemisinin derivatives are widely used antimalarial drugs. There is some evidence from in vitro, animal and clinical studies that hemoglobinopathies may alter their disposition and antimalarial activity.
T. Davis (7795394) +3 more
core +2 more sources
ABSTRACT Background Sickle cell disease (SCD) is a chronic and life‐limiting hemoglobin and systemic vascular disease. While over 1000 people have undergone hematopoietic cell transplantation (HCT) over the last 40 years, long‐term disease‐specific and health‐related quality of life data are lacking.
Gregory M. T. Guilcher +20 more
wiley +1 more source
ABSTRACT A 67‐year‐old man with decades of untreated sickle cell disease developed septic shock with multiorgan failure, splenic infarction, and marrow fibrosis; his genotype could not be confirmed. He recovered with intensive supportive care, with hydroxyurea initiated for long‐term disease modification, illustrating catastrophic infection‐triggered ...
Sara Shahidi, Gisha Mohan
wiley +1 more source
Multiple Organ‐Dysfunction Secondary to Multiple Bee Sting: A Case Report From Tanzania
ABSTRACT An 8‐year‐old boy sustained over 200 bee stings, developing airway‐threatening facial oedema requiring intubation and ICU admission, with severe anemia (Hb 3.2 g/dL), rhabdomyolysis, intravascular haemolysis and marked hepatic injury (AST 2505 U/L), yet preserved renal function.
Kelvin M. Musa +5 more
wiley +1 more source
Premarital Screening Program for Hemoglobinopathies in Karbala, Iraq
: Background: Premarital screening is a very important step in the prevention of thalassemia and other hemoglobinopathies. Aim: Evaluation of the pre-marital screening program in Karbala city to find its weak points, trying to correct them ...
Al-Najafi, Waleed Khalid
core +1 more source
ABSTRACT Sickle cell disease (SCD) with hemoglobin‐ (Hb‐) SC genotype is often considered a milder SCD variant, yet life‐threatening complications can occur. A 26‐year‐old man with HbSC disease presented with an infection triggered vaso‐occlusive crisis (VOC), acute chest syndrome (ACS), severe thrombocytopenia, Coombs‐negative hemolysis with ...
Benjamin Vieten +9 more
wiley +1 more source
Poor glycaemic control was highly prevalent among Bangladeshi patients with Type 2 diabetes mellitus. Longer diabetes duration and increased comorbidity burden were significant predictors of poor glycaemic control, highlighting the urgent need for targeted lifestyle interventions, regular monitoring, and improved health awareness to reduce diabetes ...
Md. Sakhawot Hossain +11 more
wiley +1 more source

