Results 91 to 100 of about 20,917 (253)

Differentiating β‐Thalassaemia From Iron Deficiency: Performance and Cut‐Off Dependency of More Than 40 Red Cell Discrimination Indices in a Large German Cohort

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Since the 1970s, more than 40 red blood cell–based formulas have been proposed to differentiate β‐thalassaemia trait (BTT) from iron deficiency (ID) and iron deficiency anaemia (IDA), the main causes of microcytic anaemia. In Germany, where haemoglobinopathies are rare in the autochthonous population but increasingly encountered due
Rafid Al‐Nabhan, Dani Hakimeh, Lena Oevermann   +2 more
wiley   +1 more source

Refining Residual Ischemic Stroke Risk in Anticoagulated Atrial Fibrillation Using Index Outpatient LA Diameter: The CHA2DS2‐VALa Score

Journal of Cardiovascular Electrophysiology, EarlyView.
In anticoagulated atrial fibrillation, residual ischemic stroke risk persists despite guideline‐directed therapy. In this single‐center cohort, an enlarged index outpatient left atrial diameter independently predicted stroke and improved risk stratification when added to CHA2DS2‐VA (CHA2DS2‐VALa), supporting a simple, clinically implementable ...
Sefa Erdi Ömür, Emin Koyun, Gülşen Genç Tapar, Kayıhan Karaman, Metin Karayakali, Ataç Çelik, Uğur Kulu, Yasin Taşkin   +7 more
wiley   +1 more source

Unveiling Extramedullary Hematopoiesis: A Case Report Highlighting the Causes, Symptoms, and Management Strategies

Thalassemia Reports
Extramedullary hematopoiesis (EMH) serves as a compensatory mechanism in chronic hemolytic anemias, such as thalassemia, and can result in spinal cord compression.
Konstantinos Manganas, Aikaterini Xydaki, Angeliki Kotsiafti, Olympia Papakonstantinou, Sophia Delicou   +4 more
doaj   +1 more source

Anaemia Among Mother–Child Dyads in India: Trends, Drivers, and Future Projections

Maternal &Child Nutrition, EarlyView.
ABSTRACT Anaemia among mothers and their children is a widespread public health challenge with profound consequences for individuals and societies. While anaemia has been studied separately in women and children, there remains a literature gap examining anaemia in mother‐child dyads, limiting insights on interventions that may simultaneously address ...
Sarang Pedgaonker, Trupti Meher, Monali Gupta, Suman Chakrabarti, Phuong Hong Nguyen, Shri Kant Singh, Laxmi Kant Dwivedi, Aditi, Samuel Scott   +8 more
wiley   +1 more source

α- and β-Globin Gene Mutations in Individuals with Hemoglobinopathies in the Chattogram and Sylhet Regions of Bangladesh

, 2023
Hemoglobinopathies, including α- and β-thalassemias and sickle cell disease, are among the most widely disseminated hereditary blood disorders worldwide.
Mohammad Jakir Hosen (8486724), Saeed Anwar (2130433), Tamanna Kabir (10850874), Jarin Taslem Mourosi (8486712), Shanjida Akter (14765654)   +4 more
core   +1 more source

Ensuring a reliable blood supply during a pandemic in a Caribbean setting: The Curaçao experience

Vox Sanguinis, EarlyView.
Abstract Background and Objectives National blood systems require a resilient mechanism for ensuring safe blood supply during pandemics. For small island developing states (SIDS) additional specific challenges exist not normally addressed in guidelines and the literature.
Ashley J. Duits, L. Sillé, Willem M. Smid   +2 more
wiley   +1 more source

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

The Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida, Meghann L. Smith, Sayuri Kamimura, Sebastian Vogel, Zenaide M. N. Quezado   +4 more
wiley   +1 more source

“A long bristling road full of adventure, full of discovery” gene therapy approaches in transfusion‐dependent thalassemia: The EHA‐EBMT consensus paper [PDF]

Hemasphere
HemaSphere, Volume 10, Issue 10, October 2026.
De Franceschi L, Angelucci E.
europepmc   +2 more sources

Frequency of hemoglobinopathies in the general population of newborns in Bahia-Brazil, from 2011 to 2016.

, 2018
Frequency of hemoglobinopathies in the general population of newborns in Bahia-Brazil, from 2011 to 2016.
Paula N. Fernandes (6091238), Jean T. Brito (6091244), Dona J. Alladagbin (6091235), Washington L. C. dos-Santos (336155), Geraldo G. S. Oliveira (2272111), Cácia M. Matos (6091253), Marilia B. Oliveira (6091250), Tatiana Amorim (5839073), Guilherme S. Ribeiro (90437), Luciano K. Silva (493177), Maria B. Tavares (6091241), Nadia A. Khouri (6091247), Antônio A. Lopes (6091256), Marilda S. Gonçalves (4091596)   +13 more
core   +1 more source

Venous Oxygenation Measurements in the Upper Arm: Reproducibility and Sensitivity to a Physical Challenge

Magnetic Resonance in Medicine, Volume 96, Issue 6, Page 2894-2906, December 2026.
ABSTRACT Purpose The feasibility and reproducibility of adapting the T2‐Relaxation‐Under‐Spin‐Tagging (TRUST) MRI sequence for noninvasive measurement of venous oxygenation in the upper arm were investigated, aiming to enable future in vivo validation of T2b‐oxygenation calibration curves in sickle cell disease (SCD).
J. Diogo Fernandes, Koen P. A. Baas, Matthan W. A. Caan, Bart J. Biemond, John C. Wood, Aart J. Nederveen   +5 more
wiley   +1 more source