Results 111 to 120 of about 20,917 (253)
HBQ1 Acts as a Prognostic Biomarker and Tumor Suppressor Linked to Antigen Presentation in Glioma
Cell Biochemistry and Function, Volume 44, Issue 10, October 2026.ABSTRACT Glioma is a highly aggressive brain tumor associated with substantial morbidity and mortality and with limited treatment options. This study investigates the functional role of Hemoglobin Subunit Theta 1 (HBQ1) in glioma and evaluates its potential as a prognostic biomarker. Using integrated bioinformatics approaches, we demonstrated that HBQ1
Cheng Xie +5 more
wiley +1 more source
Frequency of the hemoglobinopathies in patients with on hemodialysis in Salvador, Brazil.
, 2018 Frequency of the hemoglobinopathies in patients with on hemodialysis in Salvador, Brazil.
Paula N. Fernandes (6091238) +13 more
core +1 more source
The Role of Ferroptosis Induced by Iron Overload in Osteoblast and Osteoclast Function
Cell Biology International, Volume 50, Issue 10, October 2026.ABSTRACT Iron overload disrupts bone homeostasis by suppressing osteoblast survival and mineralization, while promoting osteoclastogenesis. As a programmed cell death driven by iron‐dependent lipid peroxidation and glutathione peroxidase 4 (GPX4) downregulation. This study investigated the role of ferroptosis in bone cells under iron overload. Exposure
Supagarn Sooksawanwit +9 more
wiley +1 more source
Hemoglobinopathies, G6PD Deficiency, and Hereditary Elliptocytosis in Bahrain
, 2011 The native population of Bahrain has a high prevalence of hemoglobinopathies and G6PD deficiency, probably as a result of past malarial endemism. We used the Biorad-Variant hemoglobin testing system for primary screening of hemoglobinopathies in 20,000 ...
Dash, Sumitra
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Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT This case highlights that severe complications of non‐transfusion‐dependent β‐thalassemia may be preventable with appropriate monitoring and timely intervention; however, once established, multisystem complications can be challenging to treat.
Oldooz Aloosh +2 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT In children with unexplained multisystem involvement—global developmental delay, dysmorphism, skeletal anomalies, and severe transfusion‐dependent anemia—especially from consanguineous families, whole‐exome sequencing should be pursued early to enable timely diagnosis, proactive iron chelation, and genetic counseling.
Arimanda Chaitanya Laasya Reddy +5 more
wiley +1 more source
Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.Sickle cell disease inflammation emerges from interconnected cytokine networks. Immune‐informatics integrates multi‐omics, network biology and artificial intelligence to decode inflammatory signatures, predict complications and identify precision therapeutic targets. Abstract Background Sickle cell disease (SCD) is characterised by chronic inflammation
Emmanuel Ifeanyi Obeagu +1 more
wiley +1 more source
Artemisinin therapy for malaria in hemoglobinopathies: A systematic review
, 2018 © The Author(s) 2018. Artemisinin derivatives are widely used antimalarial drugs. There is some evidence from in vitro, animal and clinical studies that hemoglobinopathies may alter their disposition and antimalarial activity.
T. Davis (7795394) +3 more
core +2 more sources
Hemoglobinopathies types and their peculiarities in India
Hemoglobinopathies, including thalassemias and sickle cell disorders are among the most prevalent inherited autosomal recessive blood disorders globally and pose significant public health challenges in India.
Ткаченко, Олена Вікторівна +2 more
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