Results 101 to 110 of about 20,435 (244)
Detection of Pancreatic Cancer via Specific Metabolite Markers: A Metabolomics Approach
Health Science Reports, Volume 9, Issue 9, September 2026.ABSTRACT Background and Aims Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies worldwide because most patients are diagnosed at advanced stages when curative treatment is no longer feasible. Metabolomics has emerged as a promising strategy for identifying biochemical alterations associated with early tumor development ...
Mohammad Javad Roustaye Gourabi +8 more
wiley +1 more source
Prenatal diagnosis of hemoglobinopathies in Turkey: Hacettepe experience
, 1996 Prenatal diagnosis of hemoglobinopathies was performed in 250 fetuses at risk for hemoglobinopathies. The main diagnostic procedures were in vitro hemoglobin synthesis analysis in fetal blood and analysis of DNA obtained from chorionic villus samples ...
Beksaç, Sinan +7 more
core +1 more source
Health Science Reports, Volume 9, Issue 9, September 2026.ABSTRACT Background and Aims Thalassemia is an inherited hemoglobin disorder characterized by ineffective erythropoiesis, chronic anemia, and progressive multisystem complications that require lifelong management. Current treatment relies on regular red blood cell transfusions, iron chelation therapy, and supportive multidisciplinary care, while ...
Fnu Zainab +3 more
wiley +1 more source
Hemoglobinopathies, G6PD Deficiency, and Hereditary Elliptocytosis in Bahrain
, 2011 The native population of Bahrain has a high prevalence of hemoglobinopathies and G6PD deficiency, probably as a result of past malarial endemism. We used the Biorad-Variant hemoglobin testing system for primary screening of hemoglobinopathies in 20,000 ...
Dash, Sumitra
core +1 more source
IMPORTANCE OF IMPLEMENTING PROGRAM SCREENING NEONATAL HEMOGLOBINOPATHIES IN CAPE VERDE
National Journal of Medical Research, 2015 Hemoglobinopathies are hereditary blood diseases, the most frequent sickle cell anemia. To date not have curative treatment, unless bone marrow transplant, which has yet been carried out experimentally.
Leonel Barbosa Gonçalves
doaj
Strategies and mechanisms of precision genome engineering: From gene editing to genome writing
iMetaOmics, Volume 3, Issue 3, September 2026.In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang +19 more
wiley +1 more source
Dificulties on the laboratorial diagnosis of hemoglobinopathies
, 2007 There are various types of hemoglobinopathies that are characterized by variants of abnormal hemoglobins (eg. Hb S, HbC, unstables Hb, etc.) and thalassemias (eg. alpha, beta, beta/delta, etc.).
Bonini-Domingos, Claudia R. [UNESP] +1 more
core
Genome editing strategies for treating β-hemoglobinopathies
, 2020 β-hemoglobinopathies including sickle cell disease (SCD) and β-thalassemia are debilitating, painful diseases and a major cause of global mortality and health disparities. Currently, there is no cure for the majority of patients with β-hemoglobinopathies
Park, So Hyun
core
Erythrocytapheresis as a novel treatment option for adult patients with pyruvate kinase deficiency
Haematologica, 2020 Rawia F.G. Jensen +4 more
doaj +1 more source
The Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.Abstract Accurate drug concentration measurement is essential for precision pharmacotherapy, but conventional therapeutic drug monitoring (TDM) requires venous sampling, increasing patient burden, and potentially limiting participation in TDM and model‐informed precision dosing (MIPD).
Hari Prabhath Tummala +5 more
wiley +1 more source