Results 11 to 20 of about 24,308 (321)

Early Screening of Hemoglobinopathy in Indonesia Using Erythrocyte Indices [PDF]

Indonesian Biomedical Journal, 2017
BACKGROUND: The mutation spectrums of hemoglobinopathy are different among populations that yield a different result of erythrocyte indices. Calculation of erythrocyte indices with some formula has been reported to differentiate between hemoglobinopathy ...
Yenny Surjawan, Hwee Lian Tan, Rahajuningsih Dharma Setiabudy, Wiwik Rositawati   +3 more
doaj   +6 more sources

Distribution of Hemoglobinopathy in Nepalese Population

Journal of Nepal Health Research Council, 2020
Background: Sickle cell and thalassemia are the inherited disorders of globin chain synthesis, and are the most common monogenic disease worldwide. This study aims to find the distribution of hemoglobinopathies (sickle cell and thalassemia) cases in ...
Rekha Manandhar Shrestha, Roshan Pandit, Udaya Kumar Yadav, Rameshwar Das, Binod Kumar Yadav, Harish Chandra Upreti   +5 more
doaj   +2 more sources

Diagnosis of patients with hemoglobinopathies including α-thalassemia in a laboratory with limited resources

Iraqi Journal of Hematology, 2020
BACKGROUND: Diagnosis of α-thalassemia can be challenging as it is clinically insignificant in the majority of patients who are presented with one or two α-gene deletion, it cannot be always suspected from the red cell indices, and the confirmatory tests
Abbas Hashim Abdulsalam, Subh Salim Al-Mudallal, Nidhal Karim Al-Rahal   +2 more
doaj   +2 more sources

Molecular characterization of thalassemia and hemoglobinopathy in Southeastern China

Scientific Reports, 2019
Thalassemia and hemoglobinopathy are two common inherited disorders, which are highly prevalent in southern China. However, there is little knowledge on the genotypes of thalassemia and hemoglobinopathy in Southeastern China.
Liangpu Xu, Meihuan Chen, Min Zhang
exaly   +2 more sources

Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients [PDF]

Human Genomics, 2017
Background: Human erythropoiesis is characterized by distinct gene expression profiles at various developmental stages. Previous studies suggest that fetal-to-adult hemoglobin switch is regulated by a complex mechanism, in which many key players still ...
Ali, Bassam R., Chondrou, Vasiliki, John, Anne, Kastrinou, Vlasia, Katsila, Theodora, Kolovos, Petros, Kourakli, Alexandra, Papachatzopoulou, Adamantia, Patrinos, George P., Pavlidaki, Alexia, Sgourou, Argyro, Symeonidis, Argiris   +11 more
core   +5 more sources

Celocentesis for early prenatal diagnosis of hemoglobinopathy

Ultrasound in Obstetrics and Gynecology, 2020
Celocentesis is an invasive technique that can provide prenatal diagnosis of single‐gene disorders, from as early as 7 weeks' gestation. The objective of this study was to examine the safety of celocentesis.
G. Makrydimas, G. Damiani, C. Jakil, V. Cigna, M. Orlandi, F. Picciotto, G. Schillaci, F. Cassarà, M. Vinciguerra, F. Leto, A. Giambona, A. Maggio, K. Nicolaides   +12 more
exaly   +2 more sources

Prevalence of thalassemia and hemoglobinopathy in eastern India: A 10-year high-performance liquid chromatography study of 119,336 cases

Asian Journal of Transfusion Science, 2016
Background: Hereditary hemoglobin (Hb) disorders are the most commonly encountered single gene disorders in India. Proper timely identification of these disorders is of paramount importance to prevent thalassemia major and clinically severe ...
S. Mondal, Saikat Mandal
exaly   +2 more sources

Hemoglobinopathy SD presenting as Hemoglobinopathy SS

Medicina, 2017
This case report shows the interaction of hemoglobin (Hb) S with Hb D. in a child previously diagnosed with sickle cell anemia based on the Hb electrophoretic migration pattern in alkaline pH.
Sonia Maria Lissa, Sergio Luiz Bach, Juliana Spezia, Railson Henneberg, Paulo Henrique da Silva   +4 more
doaj   +3 more sources

A rare case of renal medullary carcinoma without sickle cell hemoglobinopathy in a Japanese woman. [PDF]

Urol Case Rep
Ishizaki M, Hasumi M, Muramatsu K, Iijima M, Shimizu N.   +4 more
europepmc   +2 more sources

Distribution of hemoglobinopathy disorders in Saudi Arabia based on data from the premarital screening and genetic counseling program, 2011–2015 [PDF]

Journal of Epidemiology and Global Health, 2017
Eman S. Alsaeed, Ghada N. Farhat, Abdullah M. Assiri, Ziad A. Memish, Elawad M. Ahmed, Mohammad Y. Saeedi, Mishal F. Al-Dossary, Hisham Bashawri   +7 more
openalex   +2 more sources