Results 21 to 30 of about 11,317 (250)

Recent Advances in Sickle-Cell Disease Therapies: A Review of Voxelotor, Crizanlizumab, and L-glutamine

open access: yesPharmacy, 2022
Sickle-cell disease (SCD) is an inherited hemoglobinopathy, causing lifelong complications such as painful vaso-occlusive episodes, acute chest syndrome, stroke, chronic anemia, and end-organ damage, with negative effects on quality of life and life ...
Michael Migotsky   +2 more
doaj   +1 more source

Evaluation of Glycated Albumin (GA) and GA/Hba1c Ratio for Diagnosis of Diabetes and Glycemic Control: A Comprehensive Review [PDF]

open access: yes, 2017
Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and ...
Abdolrahim, Mojgan   +6 more
core   +3 more sources

Fetomaternal outcome of pregnancy with hemoglobinopathy [PDF]

open access: yesNew Indian Journal of OBGYN
Objectives: The objectives of this study are to determine the obstetric and neonatal outcome in pregnancy with hemoglobinopathy. Methods and materials: A prospective observational study to evaluate maternal and neonatal outcome in pregnant women with ...
Bivarani Goswami   +2 more
doaj   +1 more source

Positive predictive value of diagnosis coding for hemolytic anemias in the Danish National Patient Register [PDF]

open access: yes, 2016
PURPOSE: The nationwide public health registers in Denmark provide a unique opportunity for evaluation of disease-associated morbidity if the positive predictive values (PPVs) of the primary diagnosis are known.
Frederiksen, Henrik   +3 more
core   +2 more sources

Hb Santa Juana (β 108(G10) Asn > Ser): a low oxygen affinity hemoglobin variant in a family of Bosnian background

open access: yesHematology, 2023
We present a family that carries the β-hemoglobin variant Hb Santa Juana (HBB:c.326A>G, β 108(G10) Asn>Ser), also known as Hb Serres, in three generations. All affected family members had an anomal hemoglobin fraction as detected by HPLC but normal blood
N. P. Wildenberg   +3 more
doaj   +1 more source

Pattern of hemoglobinopathy among the young tribes of West Bengal: A completely different scenario from Rest of India

open access: yesIndian Journal of Public Health, 2023
Hemoglobinopathy is a major concern among the tribal population which constitutes 8.6% of the total population, and West Bengal (WB) is the home to 5.3 million tribes.
Jyoti Shaw   +4 more
doaj   +1 more source

Modification and Assessment of the Bedside Pediatric Early Warning Score in the Pediatric Allogeneic Hematopoietic Cell Transplant Population [PDF]

open access: yes, 2018
OBJECTIVES: To determine the validity of the Bedside Pediatric Early Warning Score system in the hematopoietic cell transplant population, and to determine if the addition of weight gain further strengthens the association with need for PICU admission.
Cater, Daniel T.   +3 more
core   +2 more sources

Investigation of thrombin generation assay to predict vaso-occlusive crisis in adulthood with sickle cell disease

open access: yesFrontiers in Cardiovascular Medicine, 2022
IntroductionSickle cell disease (SCD) is an inherited hemoglobinopathy disorder. The main consequence is synthesis of hemoglobin S leading to chronic hemolysis associated with morbidity. The aim of this study was to investigate Thrombin Generation Assay (
Guillaume Feugray   +8 more
doaj   +1 more source

Metastatic SMARCB1-Deficient Renal Medullary Carcinoma without Hemoglobinopathy with Durable and Dramatic Response to Pembrolizumab plus Lenvatinib: Case Report

open access: yesCase Reports in Oncology
Introduction: Renal medullary carcinoma (RMC) is a rare form of renal cell carcinoma (RCC) that is typically associated with a loss of function in SMARCB1 and diagnosis of sickle cell or other hemoglobinopathy.
William McCamy   +4 more
doaj   +1 more source

Review of clinical and hematological profile of hemoglobin D cases in a single centre

open access: yesJournal of Marine Medical Society, 2023
Introduction: Hemoglobin D Punjab is a common hemoglobin D variant, which is essentially known to cause a mild disease even in homozygous state. Heterozygous state of hemoglobin D Punjab with sickle cell is the only presentation when a severe disease may
Neha Singh, Tulika Seth, Seema Tyagi
doaj   +1 more source

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