Results 21 to 30 of about 9,800 (200)

Fetomaternal outcome of pregnancy with hemoglobinopathy [PDF]

New Indian Journal of OBGYN
Objectives: The objectives of this study are to determine the obstetric and neonatal outcome in pregnancy with hemoglobinopathy. Methods and materials: A prospective observational study to evaluate maternal and neonatal outcome in pregnant women with ...
Bivarani Goswami, Panchanan Das, K. Monesha   +2 more
doaj   +1 more source

Hb Santa Juana (β 108(G10) Asn > Ser): a low oxygen affinity hemoglobin variant in a family of Bosnian background

Hematology, 2023
We present a family that carries the β-hemoglobin variant Hb Santa Juana (HBB:c.326A>G, β 108(G10) Asn>Ser), also known as Hb Serres, in three generations. All affected family members had an anomal hemoglobin fraction as detected by HPLC but normal blood
N. P. Wildenberg, C. Rossi, A. E. Kulozik, J. B. Kunz   +3 more
doaj   +1 more source

Pattern of hemoglobinopathy among the young tribes of West Bengal: A completely different scenario from Rest of India

Indian Journal of Public Health, 2023
Hemoglobinopathy is a major concern among the tribal population which constitutes 8.6% of the total population, and West Bengal (WB) is the home to 5.3 million tribes.
Jyoti Shaw, Rudra Ray, Sunistha Bhattacharjee, Anjan Kumar Dasgupta, Maitreyee Bhattacharyya   +4 more
doaj   +1 more source

Metastatic SMARCB1-Deficient Renal Medullary Carcinoma without Hemoglobinopathy with Durable and Dramatic Response to Pembrolizumab plus Lenvatinib: Case Report

Case Reports in Oncology
Introduction: Renal medullary carcinoma (RMC) is a rare form of renal cell carcinoma (RCC) that is typically associated with a loss of function in SMARCB1 and diagnosis of sickle cell or other hemoglobinopathy.
William McCamy, Maryam Yousefiasl, Maria Tretiakova, Minal Jagtiani, Evan Hall   +4 more
doaj   +1 more source

Investigation of thrombin generation assay to predict vaso-occlusive crisis in adulthood with sickle cell disease

Frontiers in Cardiovascular Medicine, 2022
IntroductionSickle cell disease (SCD) is an inherited hemoglobinopathy disorder. The main consequence is synthesis of hemoglobin S leading to chronic hemolysis associated with morbidity. The aim of this study was to investigate Thrombin Generation Assay (
Guillaume Feugray, Fiston Kasonga, Maximilien Grall, Cécile Dumesnil, Ygal Benhamou, Valery Brunel, Véronique Le Cam Duchez, Agnès Lahary, Paul Billoir   +8 more
doaj   +1 more source

Acute Ischemic Stroke in Sickle Cell Disease Challenges for Thrombolysis

Dubai Medical Journal, 2020
Sickle cell disease (SCD) is a hemoglobinopathy disorder that was recognized in 1949. Stroke is one of the most devastating complications of this disorder.
Amal Al Hashmi, Sanjith Aaron
doaj   +1 more source

Recent Advances in Sickle-Cell Disease Therapies: A Review of Voxelotor, Crizanlizumab, and L-glutamine

Pharmacy, 2022
Sickle-cell disease (SCD) is an inherited hemoglobinopathy, causing lifelong complications such as painful vaso-occlusive episodes, acute chest syndrome, stroke, chronic anemia, and end-organ damage, with negative effects on quality of life and life ...
Michael Migotsky, Molly Beestrum, Sherif M. Badawy   +2 more
doaj   +1 more source

Prognostic significance of mutated genes in megakaryocytic disorders

Oncology Reviews, 2019
Megakaryopoiesis is a process during which platelets that play a major role in hemostasis are produced due to differentiation and maturation of megakaryocytic precursors.
Ali Amin Asnafi, Mohammad bagher Mohammadi, Hadi Rezaeeyan, Nader Davari, Najmaldin Saki   +4 more
doaj   +1 more source

Effect of Red Blood Cell Transfusion on Inflammatory and Angiogenic Pathways in Patients With Sickle Cell Disease

American Journal of Hematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is a chronic inflammatory state, characterized by increased plasma values of inflammatory and angiogenic proteins. Although red blood cell (RBC) transfusion is known to have immunomodulatory effects in other conditions, its potential effects on the inflammatory state in SCD remain largely unknown.
Lydian A. de Ligt, Sanjay R. Thakoerdin, Maud Zwolsman, Gaby Stegemann, Hanke Matlung, Taco W. Kuijpers, Bart J. Biemond, Karin Fijnvandraat, Robin van Bruggen, Erfan Nur   +9 more
wiley   +1 more source

Radiological findings of Posterior Reversible Encephalopathy Syndrome in transplanted children previous affected by hemoglobinopathy: A neuroimaging retrospective analysis

European Journal of Radiology Open, 2019
To evaluate, by Magnetic Resonance Imaging, if there is a typical pattern or severity of PRES in transplanted children for hemoglobinopathy. Secondary point was to investigate the pattern and severity of PRES in children with thalassemia-THAL and sickle ...
Eliseo Picchi, Francesca Di Giuliano, Simone Marziali, Silvia Minosse, Valentina Ferrazzoli, Valerio Da Ros, Javid Gaziev, Chiara Adriana Pistolese, Roberto Floris, Francesco Garaci   +9 more
doaj   +1 more source