Results 51 to 60 of about 9,398 (186)

Acute splenomegaly, haemolysis, and thrombocytopenia following luspatercept initiation in a patient with transfusion‐dependent thalassaemia: A case report

British Journal of Haematology, EarlyView.
Summary Patients with transfusion‐dependent thalassaemia (TDT) require chronic, life‐sustaining red blood cell transfusions, which contribute to iron overload and associated morbidity and mortality. Luspatercept, an inhibitor of the transforming growth factor‐beta pathway, decreases transfusion requirements in a subset of transfusion‐dependent β ...
Bianca Zaidel, Stephanie Garland, Hayley Merkeley   +2 more
wiley   +1 more source

Predictors of impending acute chest syndrome in patients with sickle cell anaemia. [PDF]

, 2020
Acute chest syndrome (ACS) is a major complication of sickle cell anaemia (SCA) and a leading cause for hospital admissions and death. We aimed to study the spectrum of clinical and laboratory features of ACS and to assess the predisposing factors and ...
Al-Busaidi, Ikhlas, Al-Salami, Bushra, Alkindi, Salam, Ballas, Samir K., Pathare, Anil, Raniga, Samir   +5 more
core   +1 more source

Inherited hemolytic disorders with high occurrence of b-thalassemia in Sindhi community of Jabalpur town in Madhya Pradesh, India [PDF]

, 2010
Hereditary hemolytic disorders such as hemoglobin disorders, β-thalassemia syndrome, G6PD deficiency, and ABO and Rhesus blood groups are the most common public health problems in India.
Balgir, RS
core   +1 more source

Glycated albumin and fructosamine do not improve accuracy of glycaemic control assessment in patients with conditions reported to affect HbA1c reliability

Diabetic Medicine, EarlyView.
Abstract Aims HbA1c testing in African populations may be limited due to high prevalence of hemoglobinopathies, anaemia, malaria and renal impairment. We aimed to assess the performance of glycated albumin (GA) and fructosamine in comparison to HbA1c for determining glycaemic control in Africans living with type 2 diabetes.
Anxious J. Niwaha, Priscilla A. Balungi, Timothy J. McDonald, Andrew T. Hattersley, Beverley M. Shields, Moffat J. Nyirenda, Angus G. Jones   +6 more
wiley   +1 more source

Time in range—A new gold standard in type 2 diabetes research?

Diabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2342-2362, May 2025.
Abstract Glycated haemoglobin (HbA1c) is currently the gold standard outcome measure for type 2 diabetes trials. Time in range is a continuous glucose monitoring (CGM) metric defined as the proportion of time in euglycemia (3.9–10.0 mmol/L) and may be valuable not only in type 1 diabetes clinical trials but also as an endpoint in type 2 diabetes trials.
Ashni Goshrani, Rose Lin, David O'Neal, Elif I. Ekinci   +3 more
wiley   +1 more source

جداسازی زنجيره‌های گلوبين به روش کروماتوگرافی تعويض يونی در تشخيص هموگلوبينوپاتی‌ها [PDF]

, 2008
زمينه و هدف: هموگلوبينوپاتی‌ها در اثر نقص در ژن سنتز کننده زنجيره‌های هموگلوبين بوجود می‌آيند. در مواقعی که موتاسيون در ژن زنجيره‌های آلفا يا بتا بصورتی باشد که تغيير بار الکتريکی هموگلوبين محسوس نباشد، برای تفکيک می‌توان از کروماتوگرافی تعويض يونی بهره ...
حسينی گوهری, لادن, شمسيان, بی بی شهین, مستعان, لیلا, معينی عليشاه, فاطمه   +3 more
core  

Trends in prevalence of anaemia among people living with HIV in the UK: 20 cross‐sectional analyses using population‐based electronic primary healthcare records

HIV Medicine, EarlyView.
Abstract Background People living with HIV have a greater prevalence of anaemia compared with people without HIV, which increases the risk of associated morbidity and premature mortality. Risk factors for anaemia among people living with HIV have changed in recent decades due to new antiretroviral therapy (ART), increased uptake of ART and increasing ...
George B. Freer, Jennifer Cooper, Krishnarajah Nirantharakumar, G. Neil Thomas, Tiffany E. Gooden   +4 more
wiley   +1 more source

Simultaneous occurrence of advanced neuroblastoma and acute lymphoblastic leukemia: a case report [PDF]

, 2011
Neuroblastoma is the most common extracranial solid tumor in children. The cooccurrence of neuroblastoma and acute lymphoblastic leukemia is rare. We report a rare case of advanced-stage neuroblastoma in a 3.5-year-old girl that was accompanied by ...
Fekri, Kiavash., Haghi, Sabahat., Jaseb, Kaveh., Pedram, Mohammad., Vafaie, Majid.   +4 more
core   +1 more source

Economic burden of sickle cell disease in Australia

Internal Medicine Journal, EarlyView.
Abstract Background Sickle cell disease (SCD) is an inherited condition that impairs red blood cell function, posing a substantial health burden on patients. As the prevalence of SCD in Australia rises due to migration, discussions surrounding treatment and management strategies are becoming more prominent. Aims Australia lacks a dedicated study on the
Steve Nwokeocha, Helen E. Haysom, Cameron Wellard, Tracy Roberts, Mwayi Kachapila, Melissa Chee, Dennis Petrie, Zoe K. McQuilten, Neil Waters, Anthea Greenway, Kylie Mason, Anna Nelson, Zane Kaplan, P. Joy Ho, Erica M. Wood, Adam Irving, on behalf of the Australian Haemoglobinopathy Registry   +16 more
wiley   +1 more source

HEMOGLOBINOPATHY

Hemoglobinopathies are a group of severe hereditary blood diseases caused by a violation of the structure of hemoglobin or a decrease in the synthesis of one or more globin chains. The clinical picture is extremely varied. Common symptoms are hemolytic anemia, enlarged spleen, and bone damage.
openaire   +2 more sources