Results 61 to 70 of about 9,800 (200)

Prevalence, Characteristics, and Determinants of Chronic Pain among Thalassemic Patients at King Abdulaziz University Hospital

open access: yesJournal of Applied Hematology
BACKGROUND: Thalassemia is a hereditary hemoglobinopathy characterized by inadequate or absent globin synthesis. This study aims to assess the prevalence and incidence of chronic pain in individuals with thalassemia within our population and further ...
Adel F. Al-Marzouki   +12 more
doaj   +1 more source

Prediction of neutrophil nadir and recovery following paediatric haematopoietic cell transplantation with busulfan conditioning

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 568-578, February 2026.
Aims In haematopoietic cell transplantation (HCT), neutropenia resulting from myelosuppression is an expected endpoint following busulfan‐based conditioning. However, if prolonged, neutropenia can lead to complications like serious infection and death.
Beth Apsel Winger   +6 more
wiley   +1 more source

Asymtomatic essential thrombocythemia in a child: a rare case report

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2013
Essential thrombocythemia is a rare myeloproliferative disorder in pediatrics. This myeloproliferative disorder is charactherized by thrombocytosis and hyperplasia of megakaryocytes in the bone marrow. Other cell lines are not involved.JAK2V617Fmutations
Majid Vafaie   +4 more
doaj  

Vaping‐Induced Erythrocytosis Resolved With Cessation of e‐Cigarette Use

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Vaping use is a global health concern with multiple adverse general health effects. We report a young man with vaping‐induced erythrocytosis that resolved following cessation of e‐cigarette use. Presence of erythrocytosis without a history of hypoxia or associated medications should prompt a thorough investigation for secondary causes ...
Jenyvette Hsia   +4 more
wiley   +1 more source

A Nonhuman Primate Transplantation Model to Evaluate Hematopoietic Stem Cell Gene Editing Strategies for β-Hemoglobinopathies

open access: yesMolecular Therapy: Methods & Clinical Development, 2018
Reactivation of fetal hemoglobin (HbF) is a promising approach for the treatment of β-hemoglobinopathies and the targeting of genes involved in HbF regulation is under intensive investigation. Here, we established a nonhuman primate (NHP) transplantation
Olivier Humbert   +4 more
doaj   +1 more source

Single‐Position Peptide Clustering for Peptidomics Reveals Novel Disease Biomarkers and Dysregulated Proteolytic Characteristics

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
A novel amino acid (aa)‐score‐based single‐position peptide clustering strategy is developed for peptidomics, enabling precise profiling of protein proteolysis in plasma from β‐thalassemia cohort. The method identifies new aa position‐based peptide cluster biomarkers validated by heavy‐labeled peptides, visualizes aggregated changes, uncovers disease ...
Na Li   +13 more
wiley   +1 more source

Erythropoiesis in health and disease: Distinguishing defective and ineffective erythropoiesis

open access: yesHemaSphere, Volume 10, Issue 1, January 2026.
Abstract Erythropoiesis is a finely regulated process ensuring continuous red blood cell production to maintain oxygen delivery. Disruptions in this process give rise to defective erythropoiesis, characterized by impaired lineage commitment and progenitor development, and ineffective erythropoiesis (IE), marked by expansion of erythroid progenitors ...
Sara El Hoss   +3 more
wiley   +1 more source

T-cell Acute Lymphoblastic Leukemia with del (7) (q11.2q22) and Aberrant Expression of Myeloid Markers

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2013
T cell acute lymphoblastic leukemia (ALL) is an invasive disease with a higher incidence in children and adolescents. In terms of Immunophenotype, T-ALL is positive for CD2, CD7, CD34 and HLA-DR, and the level of these markers is increased with ...
Ahmad Ahmadzadeh   +5 more
doaj  

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