Results 81 to 90 of about 9,800 (200)

A Rational Approach to Pharmacotherapy in Pregnancy

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen   +2 more
wiley   +1 more source

Targeted Carrier Screening for Thalassemia, Hereditary Deafness, and Spinal Muscular Atrophy: A Feasible Approach for Preventing Birth Defects in China's Community Healthcare System

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
Current carrier screening primarily focuses on high detection rates and broad testing ranges. We approach the issue from the perspective of a community physician, evaluating the suitability of carrier screening based on factors such as cost, ease of report interpretation, and compliance issues.
Zhihui Wang   +6 more
wiley   +1 more source

Genotype Differences and Hydroxyurea Utilization Among Adults With Moderate to Severe Sickle Cell Disease

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 1, January 2026.
ABSTRACT Backgrounds Hydroxyurea (HU) remains underutilized in adults with sickle cell disease (SCD) despite proven benefits. Current HU guidelines primarily target sickle cell anemia (SCA), overlooking other genotypes. Objectives This study examined HU utilization patterns across genotypes among adults considered to have moderate to severe SCD ...
Siang‐Hao Cheng   +4 more
wiley   +1 more source

Knowledge Gaps and Controversies on Cardiopulmonary Exercise Testing in the Assessment of Pulmonary Vascular Disease: An Official Statement of the Pulmonary Vascular Research Institute Exercise and Right Ventricular Function Task Force

open access: yesPulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Exercise testing has long been essential for evaluating diagnosis, prognosis, and functional status in pulmonary hypertension (PH). Recent advances have clarified its role in defining reference values and prognostic markers. Nonetheless, substantial knowledge gaps persist regarding the implementation of invasive cardiopulmonary exercise ...
Aaron B. Waxman   +20 more
wiley   +1 more source

RhD‐negative red blood cell use and conservation strategies in the Region of Southern Denmark

open access: yesVox Sanguinis, Volume 121, Issue 1, Page 73-80, January 2026.
Abstract Background and Objectives Suboptimal use of RhD‐negative red blood cells (RBCs) can lead to reduced inventories of this scarce resource. Prevention of D‐alloimmunization is particularly important for RhD‐negative females of childbearing potential (FCPs).
Emil Ainsworth Jochumsen   +3 more
wiley   +1 more source

Hemoglobinopathy and COVID-19

open access: yesHematology, Transfusion and Cell Therapy, 2021
Rujittika Mungmunpuntipantip   +1 more
doaj   +1 more source

Exploring low haemoglobin density as a no‐added‐cost screening marker to assess iron deficiency

open access: yesVox Sanguinis, Volume 121, Issue 1, Page 35-42, January 2026.
Abstract Background and Objectives Iron deficiency (ID), with or without anaemia, affects over 1 billion people globally. Early detection is essential, but current diagnostic tools may be costly, logistically complex and not widely accessible. This study evaluates low haemoglobin density percentage (LHD%), derived from mean corpuscular haemoglobin ...
Jesse Qiao, Sherif Rezk, Gagan Mathur
wiley   +1 more source

Co-Existence of Hereditary Pyrimidine 5'-Nucleotidase Deficiency and Heterozygous α-Thalassemia: A Case Presentation

open access: yesTurkish Journal of Hematology, 2012
A. Agapidou   +9 more
doaj   +1 more source

Knowledge and attitude toward hemoglobinopathies premarital screening program among unmarried population in western Saudi Arabia [PDF]

open access: diamond, 2018
Safia Mohammad Binshihon   +6 more
openalex   +1 more source

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