Results 1 to 10 of about 4,170 (243)
"Pseudo-Abnormal" Hemoglobins [PDF]
Abstract Three examples of artefactual "pseudo-abnormal" hemoglobins were observed in the course of starch block electrophoresis analysis of over 400 specimens. In fresh samples from the same patients, these components were no longer demonstrable.
H A, PEARSON, J V, McCOO, S L, LEIKIN
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The First Documented Case of Hb South Florida Variant in Portugal
We present a 39-year-old male, previous smoker, with no other known cardiovascular risk factors. He was referred to Internal Medicine for study of thrombophilia, because of repeated deep vein thrombosis.
Marta Braga Martins +3 more
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The case of hemoglobinopathy E
Abnormal unstable hemoglobins are common in certain geographic areas (Hb S, Hb C, Hb E, Hb D). The clinical manifestations in carriers of abnormal hemoglobins may be absent or expressed in the form of severe hemolytic anemia with high mortality.
Yu. I. Kunakov +5 more
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Incidence of hemoglobinopathies and spatialization of newborns with sickle cell trait in Mato Grosso do Sul, Brazil [PDF]
Objective To evaluate the incidence of variant hemoglobins of newborn samples from the Neonatal Screening Center in the state of Mato Grosso do Sul, Brazil, and to analyze the distribution and spatial autocorrelation of newborns with sickle cell trait.
Priscila de Matos Cândido-Bacani +7 more
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As anormalidades estruturais da hemoglobina estão entre as doenças genéticas mais comumente encontradas nas populações humanas. O Laboratório de Hemoglobinopatias do Departamento de Patologia Clínica da Faculdade de Ciências Médicas da Universidade ...
Elza M. Kimura +6 more
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As hemoglobinopatias, distúrbios geneticamente determinados da hemoglobina (Hb) humana, estão presentes com freqüência elevada em várias partes do mundo, sendo que no Brasil as Hb anormais S e C são as mais prevalentes.
Wanessa L. P. Vivas +3 more
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Studies on Abnormal Hemoglobins [PDF]
Abstract 1. It could be demonstrated that of the three tested types of human hemoglobin—N (normal adult), S (sickle cell) and F (fetal)—only the reduced S compound shows tactoid and gel formation in sufficiently concentrated solutions. These physico-chemical phenomena may be used for the qualitative identification of S hemoglobin.
AMOZ I. CHERNOFF, KARL SINGER
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Thalassemias are a heterogeneous group of inherited disorders characterized by a microcytic hypochromic anemia and an imbalance in the synthesis of the globin-chains. Hb C is the second most frequently variant of hemoglobin found in Brazil.
Claudia R. Bonini-Domingos +4 more
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Reaction trajectory revealed by a joint analysis of protein data bank. [PDF]
Structural motions along a reaction pathway hold the secret about how a biological macromolecule functions. If each static structure were considered as a snapshot of the protein molecule in action, a large collection of structures would constitute a ...
Zhong Ren
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NEW REPORT OF KOLN HEMOGLOBIN FROM COUNTRYSIDE/INTERIOR OF SÃO PAULO
Introduction: Hemoglobinopathies are considered a major public health problem in many countries, including Brazil, a fact explained by their frequency, genetic diversity and clinical importance. The unstable hemoglobin group is associated with congenital
JO Rios, LR Pereira, CR Bonini-Domingos
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