Results 1 to 10 of about 4,170 (243)

"Pseudo-Abnormal" Hemoglobins [PDF]

open access: yesBlood, 1961
Abstract Three examples of artefactual "pseudo-abnormal" hemoglobins were observed in the course of starch block electrophoresis analysis of over 400 specimens. In fresh samples from the same patients, these components were no longer demonstrable.
H A, PEARSON, J V, McCOO, S L, LEIKIN
openaire   +2 more sources

The First Documented Case of Hb South Florida Variant in Portugal

open access: yesActa Médica Portuguesa, 2022
We present a 39-year-old male, previous smoker, with no other known cardiovascular risk factors. He was referred to Internal Medicine for study of thrombophilia, because of repeated deep vein thrombosis.
Marta Braga Martins   +3 more
doaj   +1 more source

The case of hemoglobinopathy E

open access: yesОнкогематология, 2014
Abnormal unstable hemoglobins are common in certain geographic areas (Hb S, Hb C, Hb E, Hb D). The clinical manifestations in carriers of abnormal hemoglobins may be absent or expressed in the form of severe hemolytic anemia with high mortality.
Yu. I. Kunakov   +5 more
doaj   +3 more sources

Incidence of hemoglobinopathies and spatialization of newborns with sickle cell trait in Mato Grosso do Sul, Brazil [PDF]

open access: yesEinstein (São Paulo), 2022
Objective To evaluate the incidence of variant hemoglobins of newborn samples from the Neonatal Screening Center in the state of Mato Grosso do Sul, Brazil, and to analyze the distribution and spatial autocorrelation of newborns with sickle cell trait.
Priscila de Matos Cândido-Bacani   +7 more
doaj   +1 more source

Identificação e caracterização de variantes novas e raras da hemoglobina humana Identification of characterization of novel and rare variants of human hemoglobin

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2008
As anormalidades estruturais da hemoglobina estão entre as doenças genéticas mais comumente encontradas nas populações humanas. O Laboratório de Hemoglobinopatias do Departamento de Patologia Clínica da Faculdade de Ciências Médicas da Universidade ...
Elza M. Kimura   +6 more
doaj   +1 more source

Heterozigose para hemoglobinopatias em doadores de sangue do Centro de Hemoterapia de Sergipe Heterozigosity to hemoglobinopathies in blood donors from the Hemotherapy Center in Sergipe, NE-Brazil

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2006
As hemoglobinopatias, distúrbios geneticamente determinados da hemoglobina (Hb) humana, estão presentes com freqüência elevada em várias partes do mundo, sendo que no Brasil as Hb anormais S e C são as mais prevalentes.
Wanessa L. P. Vivas   +3 more
doaj   +1 more source

Studies on Abnormal Hemoglobins [PDF]

open access: yesBlood, 1952
Abstract 1. It could be demonstrated that of the three tested types of human hemoglobin—N (normal adult), S (sickle cell) and F (fetal)—only the reduced S compound shows tactoid and gel formation in sufficiently concentrated solutions. These physico-chemical phenomena may be used for the qualitative identification of S hemoglobin.
AMOZ I. CHERNOFF, KARL SINGER
openaire   +1 more source

Interação entre Hb C [beta6(A3)Glu>Lys] e IVS II-654 (C>T) beta-talassemia no Brasil Hb C [beta6(A3)Glu>Lys] and IVS II - 654 (C>T) beta thalassemia interaction in Brazil

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2003
Thalassemias are a heterogeneous group of inherited disorders characterized by a microcytic hypochromic anemia and an imbalance in the synthesis of the globin-chains. Hb C is the second most frequently variant of hemoglobin found in Brazil.
Claudia R. Bonini-Domingos   +4 more
doaj   +1 more source

Reaction trajectory revealed by a joint analysis of protein data bank. [PDF]

open access: yesPLoS ONE, 2013
Structural motions along a reaction pathway hold the secret about how a biological macromolecule functions. If each static structure were considered as a snapshot of the protein molecule in action, a large collection of structures would constitute a ...
Zhong Ren
doaj   +1 more source

NEW REPORT OF KOLN HEMOGLOBIN FROM COUNTRYSIDE/INTERIOR OF SÃO PAULO

open access: yesHematology, Transfusion and Cell Therapy, 2021
Introduction: Hemoglobinopathies are considered a major public health problem in many countries, including Brazil, a fact explained by their frequency, genetic diversity and clinical importance. The unstable hemoglobin group is associated with congenital
JO Rios, LR Pereira, CR Bonini-Domingos
doaj   +1 more source

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