Results 91 to 100 of about 20,967 (222)

Ability of the rL-hemolysin proteins to induce IL-1β, IL-6 and TNF-α in human and mouse macrophages.

, 2013
(A). IL-1β, IL-6 and TNF-α levels in human THP-1 and mouse J774A.1 macrophages induced by each of the rL-hemolysin proteins for 24 h with the indicated protein concentrations. Bars show the mean ± SD of three independent experiments.
Yifei Wu (313108), Xu’ai Lin (313111), Jie Yan (119530), Shibiao Ding (313110), Huan Wang (109286), Chenglin Zhang (313109), David M. Ojcius (167589), X. Frank Yang (215426)   +7 more
core   +1 more source

Detection of Alpha-Toxin and Other Virulence Factors in Biofilms of Staphylococcus aureus on Polystyrene and a Human Epidermal Model. [PDF]

PLoS ONE, 2016
The ability of Staphylococcus aureus to successfully colonize (a)biotic surfaces may be explained by biofilm formation and the actions of virulence factors.
P M den Reijer, E M Haisma, N A Lemmens-den Toom, J Willemse, R I Koning, J A A Demmers, D H W Dekkers, E Rijkers, A El Ghalbzouri, P H Nibbering, W van Wamel   +10 more
doaj   +1 more source

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Mitotic block and delayed lethality in HeLa epithelial cells exposed to Escherichia coli BM2-1 producing cytotoxic necrotizing factor type 1 [PDF]

, 1996
The cytopathic effect (CPE) of Escherichia coli producing cytotoxic necrotizing factor type 1 (CNF1) was investigated by using a human epithelial cell (HeLa) model of infection with CNF1-producing E. coli BM2-1. This strain was shown to bind loosely, but
Nougayrède, Jean-Philippe, Valette, Annie, Mazars, Philippe, de Rycke, Jean, Oswald, Eric, Tasca, Christian, Boury, Michèle, Rycke, Jean de, Herault, Frédéric   +8 more
core  

Reversible adsorption and nonreversible insertion of Escherichia coli alpha-hemolysin into lipid bilayers [PDF]

, 1996
Alpha-Hemolysin is an extracellular protein toxin (107 kDa) produced by some pathogenic strains of Escherichia coli. Although stable in aqueous medium, it can bind to lipid bilayers and produce membrane disruption in model and cell membranes.
Goñi, F.M., Ostolaza, H., Goni, F. M., Bakás, L., Vaz, W.L., Vaz, Winchil   +5 more
core   +1 more source

Hemolysin coregulated protein 1 as a molecular gluing unit for the assembly of nanoparticle hybrid structures [PDF]

Beilstein Journal of Nanotechnology, 2016
Hybrid nanoparticle (NP) structures containing organic building units such as polymers, peptides, DNA and proteins have great potential in biosensor and electronic applications. The nearly free modification of the polymer chain, the variation of the protein and DNA sequence and the implementation of functional moieties provide a great platform to ...
Pham, Tuan Anh, Schreiber, Andreas, Sturm, Elena V., Schiller, Stefan, Cölfen, Helmut   +4 more
openaire   +5 more sources

Decoding Biothreats With FT‐ICR‐MS: Metabotyping of Bacillus cereus Spores Through Untargeted Metabolomics

Journal of Mass Spectrometry, Volume 61, Issue 7, July 2026.
ABSTRACT Genome sequencing is the gold standard for microbial identification. However, it fails to distinguish closely related species with overlapping genetic features. This is the case of Bacillus cereus and Bacillus cytotoxicus, two members of the B. cereus group with distinct pathogenic profiles. While B. cereus, a well‐known opportunistic pathogen
Maria Inês Romão, Inês Gomes, Wilson Antunes, Petr Novak, Marta Sousa Silva, Carlos Cordeiro   +5 more
wiley   +1 more source

Translocation of single‐stranded DNA through the α‐hemolysin protein nanopore in acidic solutions [PDF]

ELECTROPHORESIS, 2011
AbstractThe effect of acidic pH on the translocation of single‐stranded DNA through the α‐hemolysin pore is investigated. Two significantly different types of events, i.e. deep blockades and shallow blockades, are observed at low pH. The residence times of the shallow blockades are not significantly different from those of the DNA translocation events ...
Ranulu S S, de Zoysa, D M Milan, Krishantha, Qitao, Zhao, Jyoti, Gupta, Xiyun, Guan   +4 more
openaire   +2 more sources

Genome sequence of the pathogenic intestinal spirochete Brachyspira hyodysenteriae reveals adaptations to its lifestyle in the porcine large intestine

, 2009
Brachyspira hyodysenteriae is an anaerobic intestinal spirochete that colonizes the large intestine of pigs and causes swine dysentery, a disease of significant economic importance. The genome sequence of B.
Motro Yair, Ryan, K., Karon Ryan, Wanchanthuek Phatthanaphong, Hunter, A., Shaban, B., David J. Hampson, Barrero Roberto, Wanchanthuek, P, Nyree D. Phillips, Barrero, R., David S. Dunn, Barrero, R, Matthew I Bellgard, Moolhuijzen, Paula, Dunn David S., David S Dunn, Moolhuijzen, P., Motro, Y, Matthew I. Bellgard, La Tom, Phillips Nyree D., Hampson, D., Schibeci David, Hunter Adam, Nyree D Phillips, Shaban, B, Shaban Babak, Ryan, K, Albertyn, Z., Yair Motro, Ryan Karon, Albertyn, Z, Paula Moolhuijzen, Phillips, N., David Schibeci, Albertyn Zayed, Dunn, DS, Hampson, DJ, Babak Shaban, Motro, Y., Bellgard Matthew I., Hunter, A, Phillips, N.D., Schibeci, D, Moolhuijzen, P, Dunn, D.S., Tom La, Hampson David J., Hampson, D.J., Adam Hunter, Bellgard, MI, Roberto Barrero, Zayed Albertyn, Dunn, D., La, T, Bellgard, M., Moolhuijzen Paula, David J Hampson, Wanchanthuek, P., Phatthanaphong Wanchanthuek, La, T., Phillips, ND, Schibeci, D.   +63 more
core   +1 more source

Distribution and dynamics of epidemic and pandemic Vibrio parahaemolyticus virulence factors

Frontiers in Cellular and Infection Microbiology, 2013
Vibrio parahaemolyticus, autochthonous to estuarine, marine, and coastal environments throughout the world, is the causative agent of food-borne gastroenteritis.
Daniela eCeccarelli, Nur A Hasan, Nur A Hasan, Anwar eHuq, Anwar eHuq, Rita R Colwell, Rita R Colwell, Rita R Colwell, Rita R Colwell   +8 more
doaj   +1 more source