Results 101 to 110 of about 116,124 (310)

Erythrocytes and Vascular Function: Oxygen and Nitric Oxide

Frontiers in Physiology, 2018
Erythrocytes regulate vascular function through the modulation of oxygen delivery and the scavenging and generation of nitric oxide (NO). First, hemoglobin inside the red blood cell binds oxygen in the lungs and delivers it to tissues throughout the body
Christine C. Helms, Mark T. Gladwin, Mark T. Gladwin, Daniel B. Kim-Shapiro, Daniel B. Kim-Shapiro   +4 more
doaj   +1 more source

Pattern of AST and ALT Changes in Relation to Hemolysis in Sickle Cell Disease

, 2011
Background Elevated aminotransferase levels are commonly associated with compromised hepatic integrity from various insults. In sickle cell disease, aspartate transaminase (AST) is also released via intravascular hemolysis.
D. Ansong, D. Ocloo, K. Nsiah, V.P. Dzogbefia, A. Osei Akoto, H. Boateng   +5 more
core   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Mechanism of hemolysis after intravenous glycerol administration

, 1960
Concentrated glycerol solutions in 0.9% saline, when administered intravenously to rabbits and rats, caused considerable intravascular hemolysis, but similar solutions given to dogs had no hemolytic effect.
Gabriel G. Pinter, D. B. Zilversmit
core   +1 more source

Light‐Activatable Nitric Oxide Release via Intramolecular Electron Transfer for Tumor Pyroptosis Induction

Advanced Science, EarlyView.
This work proposes a novel strategy to fabricate unimolecular pyroptosis photoinitiators activated by deep‐red light at low light doses. It relies on a photosensitization mechanism to trigger nitric oxide (NO) release from benzisothiadiazole‐based N‐nitrosanilines without modification of nitro moieties, thereby boosting pyroptosis‐mediated ...
Chuangxin Zhang, Ruipeng Li, Yunxia Wang, Feng Liu, Liheng Feng   +4 more
wiley   +1 more source

Antiviral Immune Hemolysis

Experimental Biology and Medicine, 1973
SummaryNewcastle and parainfluenza I viruses when incubated with mouse or chick embryo erythrocytes at low multiplicity sensitized the red cells to hemolysis by antiviral antibody and complement. Two strains of influenza virus showed little or no sensitizing activity to influenza antibody.
M D, Eaton, J A, Heller
openaire   +2 more sources

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Evaluation of the red cell hemolysis in packed red cells during processing and storage

Asian Journal of Transfusion Science, 2011
Introduction : Storage of red cells causes a progressive increase in hemolysis. In spite of the use of additive solutions for storage and filters for leucoreduction, some amount of hemolysis is still inevitable.
Makroo R, Raina Vimarsh, Bhatia Aakanksha, Gupta Richa, Majid Abdul, Thakur Uday, Rosamma N   +6 more
doaj  

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

HEMOLYSIS AND AGGLUTINATION IN TRANSPLANTATION [PDF]

Journal of the American Medical Association, 1915
In studies of the conditions incident to the cause of autolysis and the dissolution of the transplant, we devoted especial attention to the influence of hemolysis and agglutination on transplants. No question is more timely than that concerning the causes of their absorption. Most authors lay great stress on the importance of eliminating the two great
openaire   +2 more sources