Results 81 to 90 of about 130,805 (311)
Advanced Science, EarlyView.An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng +9 more
wiley +1 more source
Erythrocytes and Vascular Function: Oxygen and Nitric Oxide
Frontiers in Physiology, 2018 Erythrocytes regulate vascular function through the modulation of oxygen delivery and the scavenging and generation of nitric oxide (NO). First, hemoglobin inside the red blood cell binds oxygen in the lungs and delivers it to tissues throughout the body
Christine C. Helms +4 more
doaj +1 more source
Mechanism of hemolysis after intravenous glycerol administration
, 1960 Concentrated glycerol solutions in 0.9% saline, when administered intravenously to rabbits and rats, caused considerable intravascular hemolysis, but similar solutions given to dogs had no hemolytic effect.
Gabriel G. Pinter, D. B. Zilversmit
core +1 more source
Advanced Science, EarlyView.Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu +10 more
wiley +1 more source
Moderate glucose supply reduces hemolysis during systemic inflammation
, 2018 Johannes Jägers,1 Stephan Brauckmann,2 Michael Kirsch,1 Katharina Effenberger-Neidnicht1,3 1Institute of Physiological Chemistry, University Hospital Essen, Essen, Germany; 2Clinic for Anesthesiology and Intensive Care, University Hospital Essen ...
Effenberger-Neidnicht K +3 more
core
, 2008 Hemolysis, the major cause for specimen rejection in clinical laboratories is defined as the rupture of red blood cell membranes, resulting in the release of hemoglobin into the plasma.
Kommidi, Giridhar R., 1980-
core +1 more source
Advanced Science, EarlyView.Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu +18 more
wiley +1 more source
Inhibition of thiourea-induced hemolysis by plasma
, 1968 The relative rates of hemolysis of rat erythrocytes in isotonic thiourea were determined using whole blood and washed cells. Washing the erythrocytes with isotonic saline increased the rate of hemolysis relative to that observed for cells in whole blood.
Brian L. Walker
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Advanced Science, EarlyView.Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley +1 more source