Results 121 to 130 of about 92,935 (295)

Advanced Cancer Immunotherapy via SMARCAL1 Blockade Using a Glucose‐Responsive CRISPR Nanovaccine

open access: yesAdvanced Science, EarlyView.
A glucose‐catalyzed chemodynamic strategy is proposed to activate therapeutic genome editing of SMARCAL1to improve cancer immunotherapy. This innovative design featuring Fenton reaction activity and glucose consumption ability, not only effectively synergizes to activate the cGAS‐STING pathway but also inhibits the opposing functions of interferon by ...
Yuwei Li   +8 more
wiley   +1 more source

VALIDACIÓN INTRALABORATORIO DE UNA METODOLOGÍA ANALÍTICA POR ESPECTROFOTOMETRÍA UV/VIS PARA EVALUAR EL POTENCIAL IRRITANTE OCULAR DE TENSOACTIVOS EN GLÓBULOS ROJOS INTRALABORATORY VALIDATION OF AN ANALYTICAL METHODOLOGY BY UV/VIS SPECTROMETRY IN ORDER TO EVALUATE THE OCULAR IRRITANT POTENTIAL OF TENSOACTIVES IN RED BLOOD CELLS

open access: yesVitae, 2011
Se presentan los resultados de la validación intralaboratorio para los parámetros de linealidad, repetibilidad y precisión intermedia del ensayo en glóbulos rojos, metodología in vitro empleada para evaluar la irritación ocular.
Luz A LEGUIZAMÓN B   +3 more
doaj  

Convertible ROS Nanocatalyst/Eliminator for Enhancing Tumor Radio‐Immunotherapy and Relieving Radiation Enteritis

open access: yesAdvanced Science, EarlyView.
A novel Janus Ag/Ag2S nanostructure grafted with dimer PD‐L1 affibody (AMZ) is successfully developed. AMZ can be used as ROS nanocatalyst to achieve tumor radiosensitization, and it can also act as an ROS eliminator to alleviate radiation enteritis, achieving a radiotherapy strategy characterized by “toxicity reduction and efficacy enhancement ...
Mengmeng Zhang   +12 more
wiley   +1 more source

Ferrocene‐Functionalized Black Phosphorus Nanoplatform Enables Targeted and Prolonged MRI Visualization of Atherosclerotic Plaques

open access: yesAdvanced Science, EarlyView.
Aminoferrocene is employed to modify black phosphorus, generating stable phosphorus radicals (FcP). The FcP is then functionalized with hyaluronic acid (HA) to produce the HA‐FcP radical complex, thereby developing a novel, highly efficient, sensitive, long‐lasting, and low‐heavy‐metal‐content radical contrast agent for targeted imaging of ...
Xiao Huang   +6 more
wiley   +1 more source

The Adrenal Cortex and Hemolysis [PDF]

open access: bronze, 1955
J. D. Feldman   +2 more
openalex   +1 more source

DNase I‐Mediated Chemotactic Nanoparticles for NETs Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
The neutrophil extracellular traps (NETs) play an important role in reperfusion injury in ischemic stroke. Here, considering the unique vascular localization of NETs, a DNase I‐mediated NETs‐targeting nanoparticle is developed to integrate the catalytic and chemotactic functions of DNase I and achieve the synergistic regulation of the internal and ...
Tongyu Zhang   +7 more
wiley   +1 more source

ATTACKS OF HEMOLYSIS IN RAYNAUDʼS DISEASE [PDF]

open access: green, 1921
A. Souques, Richard Moreau
openalex   +1 more source

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