Results 181 to 190 of about 89,871 (313)
Animal Models and Experimental Medicine, EarlyView.Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.We establish a simple polyamidation of carboxylic acids and ynamides to synthesize versatile piezoelectric polyamides, with the merits of 100% atom economy, no waste generation, and additive‐free as well as catalyst‐free system. Tetraphenylethene containing polyamides can generate reactive oxygen species and elicit robust immunogenic cell death ...
Xingguang Li +8 more
wiley +2 more sources
Evaluation of hemolysis in patients supported with Impella 5.5: a single center experience. [PDF]
J Cardiothorac SurgClothier JS +7 more
europepmc +1 more source
Studies on Immune Human Hemolysis [PDF]
, 1963 Carl F. Hinz, Anna Marie Mollner
openalex +1 more source
Animal Models and Experimental Medicine, EarlyView.This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin +9 more
wiley +1 more source
Functional activity of peptide ion channels in tethered bilayer lipid membranes: Review
Electrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022 Abstract Ion transport across biomembranes plays a major role in living cells. This fundamental function is normally carried out by molecules with both a hydrophobic and a hydrophilic side (amphiphilic molecules), which aggregate within the membrane forming a hydrophilic pore (the ion channel) permitting the selective translocation of permeant ions ...
Rolando Guidelli, Lucia Becucci
wiley +1 more source
ELECTROPHORETIC SEPARATION AND PROPERTIES OF MOUSE ANTIHAPTEN ANTIBODIES INVOLVED IN PASSIVE CUTANEOUS ANAPHYLAXIS AND PASSIVE HEMOLYSIS [PDF]
, 1964 Ruth S. Nussenzweig +2 more
openalex +1 more source
The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs
Advanced NanoBiomed Research, EarlyView.Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He +11 more
wiley +1 more source
Epilepsia Open, EarlyView., 2022 Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines.
Laura Bindila +11 more
wiley +1 more source
Antimicrobial Peptide‐Peptoid Macrocycles from the Polymyxin B2 Chemical Space
Angewandte Chemie, EarlyView.We optimized mixed peptide‐peptoid sequences for molecular similarity to the macrocyclic lipopeptide antibiotic polymyxin B2 (PMB2) using a genetic algorithm. Synthesis and testing of top‐scoring compounds allowed us to identify new macrocycles with similar antimicrobial activity and reduced toxicity compared to PMB2.
Etienne Bonvin +7 more
wiley +2 more sources