Results 221 to 230 of about 216,432 (383)

Bimetallic Nanozyme Amplifier for Synergistic Ferroptosis‐Cuproptosis and Metabolic Reprogramming to Reshape Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo, Kunzhao Huang, Xiaoyuan Yi, Pei Lu, Huaying Xie, Wen Li, Qingyu Zeng, Feifei He, Duo Wang, Liyan Wang   +9 more
wiley   +1 more source

Hemolysis of Human Erythrocytes by Methicillin-Resistant <i>Staphylococcus aureus</i> Is Primarily Caused by PSMα Peptides. [PDF]

Toxins (Basel)
Nygaard TK, Gao A, LaTray E, Voyich JM.
europepmc   +1 more source

Hemolysis inhibits humoral B-cell responses and modulates alloimmunization risk in patients with sickle cell disease [PDF]

, 2020
Mouli Pal, Weili Bao, Rikang Wang, Yunfeng Liu, Xiuli An, William B. Mitchell, Cheryl A. Lobo, Caterina P. Minniti, Patricia A. Shi, Deepa Manwani, Karina Yazdanbakhsh, Hui Zhong   +11 more
openalex   +1 more source

Incompatible blood transfusions in liver transplant patients with significant red cell alloantibodies [PDF]

, 1989
Cornell, FW, Fonzi, F, Hahn, LF, Ramsey, G, Starzl, TE   +4 more
core  

Trimetallic Nanozyme‐Embedded Smart Hydrogel Enables NIR‐Controlled Bacterial Killing and Oxidative Stress Alleviation

Advanced Science, EarlyView.
A microenvironment‐responsive hydrogel is developed incorporating polymyxin B‐modified AuMnCu nanozymes and dual drugs (tannic acid and tobramycin). At infection sites, it generates ROS, releases drugs responsively, and enhances mild photothermal action to disrupt bacterial redox balance.
Zehui Xiao, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +5 more
wiley   +1 more source

C3 mutations and poor pegcetacoplan response in paroxysmal nocturnal hemoglobinuria. [PDF]

Front Immunol
Rodríguez de Córdoba S, Reparaz Suevos A, González Sanz S, Fernández FJ, Vega MC, Varela EC, Lada Colunga A, Vallejo Llamas JC, Gonzalez-Rodríguez AP.   +8 more
europepmc   +1 more source

HEMOLYSIS IN DOG BLOOD: INTRAVASCULAR HEMOLYSIS AND HYPOCAPNIA

The Journal of Thoracic and Cardiovascular Surgery, 1963
openaire   +2 more sources

Hemolysis [PDF]

, 2020
openaire   +1 more source

Overcoming EGFR‐Mediated Dendritic Cell Dysfunction to Enhance Anti‐tumor Immunity in EGFR‐Mutant NSCLC by Precisely Targeting CD73 With pH‐responsive Nanocarriers

Advanced Science, EarlyView.
EGFR mutations drive ERK/c‐Jun–mediated transcriptional activation of CD73, elevating adenosine levels and fostering an immunosuppressive TME by impairing DC maturation and CD8⁺ T cell priming. The pH‐responsive nanodrug F127ZIF‐8AB680 selectively inhibits CD73, normalizes adenosine metabolism, and re‐establishes effective anti‐tumor immunity ...
Xiaoling Shang, Xudong Geng, Zixu Wang, Shumin Yuan, Shanshan Ding, Ni Liu, Xinchun Ma, Xuan Sun, Huimin Wang, Ying Sun, Xun Qu, Guangwen Ren, Yong Qiang Li, Xiuwen Wang, Yanguo Liu   +14 more
wiley   +1 more source

Innate Immunity in the Cottonmouth Watersnake (<i>Agkistrodon piscivorus</i>). [PDF]

Animals (Basel)
Merchant M, Epperson J, Baker S.
europepmc   +1 more source