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Hemolytic Anemia with Hemoglobinuria
American Journal of Clinical Pathology, 1948Hemolytic anemia with hemoglobinuria is frequently a striking clinical event indicative of extensive intravascular hemolysis. The condition lends itself to detailed study because of the morphologic abnormalities in the blood and bone marrow, the marked accumulation of hemoglobin and its derivatives in the blood plasma and urine, the aberrations of ...
D, STATS, L R, WASSERMAN, N, ROSENTHAL
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Hydroxylamines and Hemolytic Anemia
1986Hemolytic anemia, the uncompensated loss of red blood cells from the circulation, has been recognized as a side effect of drugs and other chemicals for over 50 years (Muelens, 1926; Cordes, 1926). This response is commonly associated with the aminoquinoline drugs, pamaquine and primaquine (Beutler, 1959); indeed the extensive studies carried out with ...
D J, Jollow +2 more
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Hemolytic Anemias in Pregnancy
Clinical Obstetrics and Gynecology, 1995Polymorphism exists and complicates the diagnosis of inherited hemolytic anemias. However, with linkage DNA analysis and, on occasion, with characterization of the mutant gene, it is possible to make a diagnosis on the DNA level. This technique increases our understanding of the enzymatic defect and the relationship with clinical findings.
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Medical Clinics of North America, 1980
Immune hemolytic anemia is an acquired anemia resulting from the premature destruction of red cells caused by the presence of antibody and/or complement on the red cell surface. The Coombs test, modified and improved, remains the mainstay of diagnosis.
J A, Axelson, A F, LoBuglio
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Immune hemolytic anemia is an acquired anemia resulting from the premature destruction of red cells caused by the presence of antibody and/or complement on the red cell surface. The Coombs test, modified and improved, remains the mainstay of diagnosis.
J A, Axelson, A F, LoBuglio
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Pediatric Clinics of North America, 1980
In autoimmune hemolytic anemia, individuals produce antibodies directed against one of their own erythrocyte membrane antigens. The hemolysis in autoimmune hemolytic anemia is most commonly extravascular rather than intravascular, and the liver and spleen play a major role in the clearance of the antibody-coated cells.
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In autoimmune hemolytic anemia, individuals produce antibodies directed against one of their own erythrocyte membrane antigens. The hemolysis in autoimmune hemolytic anemia is most commonly extravascular rather than intravascular, and the liver and spleen play a major role in the clearance of the antibody-coated cells.
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Archives of Internal Medicine, 1975
Warm-type autoantibodies of autoimmune hemolytic anemia (AIHA) are usually IgG but may be IgM or IgA. They are usual Rh specific. Cold-type antibodies are IgM or IgG (Donath-Landsteiner [DL] antibody). IgM antibodies are usually anit-l (occasionally anti-i) and DL antibodies anti-P.
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Warm-type autoantibodies of autoimmune hemolytic anemia (AIHA) are usually IgG but may be IgM or IgA. They are usual Rh specific. Cold-type antibodies are IgM or IgG (Donath-Landsteiner [DL] antibody). IgM antibodies are usually anit-l (occasionally anti-i) and DL antibodies anti-P.
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Cephalothin and Hemolytic Anemia
Annals of Internal Medicine, 1970Excerpt To the editor: In the May 1970 issue of the ANNALS, Drs. Weinstein and Kaplan in the article "The Cephalosporins" made the following statement: "Therapy with cephalothin and, much less comm...
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Medical Clinics of North America, 2017
Autoimmune hemolytic anemia is an acquired autoimmune disorder resulting in the production of antibodies directed against red blood cell antigens causing shortened erythrocyte survival. The disorders can present as a primary disorder (idiopathic) or secondary to other autoimmune disorders, malignancies, or infections.
Howard A, Liebman, Ilene C, Weitz
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Autoimmune hemolytic anemia is an acquired autoimmune disorder resulting in the production of antibodies directed against red blood cell antigens causing shortened erythrocyte survival. The disorders can present as a primary disorder (idiopathic) or secondary to other autoimmune disorders, malignancies, or infections.
Howard A, Liebman, Ilene C, Weitz
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Microangiopathic Hemolytic Anemia
New England Journal of Medicine, 1969IN 1917 Rous and Robertson1 suggested that fragmentation was the normal fate of the effete erythrocyte at the end of its life-span. More recently it has become recognized that erythrocytes may undergo fragmentation earlier if they are subjected to excessive trauma within the circulation.
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Human Pathology, 1983
Nowhere in the management of patients with autoimmune hemolytic anemias is the communication between clinician and laboratory personnel more important than in regard to blood transfusion. A clinical decision that blood transfusion is necessary must be tempered by the knowledge that transfusion has a greater-than-usual risk in this setting, both because
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Nowhere in the management of patients with autoimmune hemolytic anemias is the communication between clinician and laboratory personnel more important than in regard to blood transfusion. A clinical decision that blood transfusion is necessary must be tempered by the knowledge that transfusion has a greater-than-usual risk in this setting, both because
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