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Tolbutamide-induced Hemolytic Anemia
Diabetes, 1977A 67-year-old female diabetic is presented who developed a Coombs'-positive hemolytic anemia after a year of treatment with tolbutamide. An IgG antibody was identified in the patient's serum that caused the agglutination of both the patient's red blood cells and tolbutamide-coated erythrocytes in the absence of complement. Such a reaction did not occur
P, Malacarne +3 more
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Hospital Practice, 1985
Rh and ABO incompatibilities, drug reactions, and lupus are a few of the many causes of autoimmune hemolytic anemia. Among the determinants of autoimmunity involved are the class of the antibody, the biochemical composition of the antigen, the distribution of the antigen on the erythrocyte membrane, and the effector cells and molecules that are ...
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Rh and ABO incompatibilities, drug reactions, and lupus are a few of the many causes of autoimmune hemolytic anemia. Among the determinants of autoimmunity involved are the class of the antibody, the biochemical composition of the antigen, the distribution of the antigen on the erythrocyte membrane, and the effector cells and molecules that are ...
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Current Opinion in Immunology, 1994
Autoimmune hemolytic anemia (AHA) is characterized by the production of Coombs' antibodies, which are responsible for the destruction of red blood cells (RBCs). Analysis of both monoclonal anti-RBC autoantibodies derived from autoimmune New Zealand black mice and transgenic mice expressing a pathogenic IgM anti-RBC autoantibody has considerably ...
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Autoimmune hemolytic anemia (AHA) is characterized by the production of Coombs' antibodies, which are responsible for the destruction of red blood cells (RBCs). Analysis of both monoclonal anti-RBC autoantibodies derived from autoimmune New Zealand black mice and transgenic mice expressing a pathogenic IgM anti-RBC autoantibody has considerably ...
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Coagulation in the Pathophysiology of Hemolytic Anemias
Hematology, 2007AbstractCoagulation abnormalities are frequently reported in hemolytic anemias (HA). Several pathophysiologic mechanisms are common to different HA. In this review three different hemolytic disorders will be discussed.In sickle cell disease and in β-thalassemia, a thrombophilic status has been well documented as multifactorial involving hemostatic ...
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Postgraduate Medicine, 1978
The recognition, investigation, diagnosis, and treatment of hemolytic anemia are reviewed on the basis of a classification of the causes of hemolysis according to whether they are disorders of the membrane, hemoglobin, or metabolism of the erythrocyte; congenital or familial or acquired; and intrinsic or extrinsic.
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The recognition, investigation, diagnosis, and treatment of hemolytic anemia are reviewed on the basis of a classification of the causes of hemolysis according to whether they are disorders of the membrane, hemoglobin, or metabolism of the erythrocyte; congenital or familial or acquired; and intrinsic or extrinsic.
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Development of New Drugs for Autoimmune Hemolytic Anemia
Pharmaceutics, 2022Irina Murakhovskaya
exaly