Results 81 to 90 of about 33,911 (221)

Biopharmaceuticals for Cancer Treatment: An Update

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Cancer is one of the most debilitating diseases, causing profound physical and psychological impacts on patients. The global number of cancer patients has been steadily rising over the last few decades. The development of effective cancer therapies remains the primary focus in life science research, requiring a precise understanding of ...
Anupom Deb Nath, Yousuf Alam, Afsana Mustak Mim, Maksuda Akter, Mohammad Abbas Gani, Khondaker Muhammad Khairul Alam, Md. Nur Alam   +6 more
wiley   +1 more source

Multiple Myeloma as the Underlying Cause of Thrombotic Microangiopathy Leading to Acute Kidney Injury: Revisiting a Very Rare Entity

Journal of Investigative Medicine High Impact Case Reports, 2017
Thrombotic microangiopathy (TMA) describes a pathological process of microvascular thrombosis, consumptive thrombocytopenia, and microangiopathic hemolytic anemia, leading to end-organ ischemia and infarction, affecting particularly the kidney and brain.
Savneek Chugh MD, Asim Kichloo MD, Firas Jafri MD, Liga Yusvirazi MD, Robert Lerner MD   +4 more
doaj   +1 more source

Role of eculizumab in a pediatric refractory gemcitabine-induced thrombotic microangiopathy: a case report

Journal of Medical Case Reports, 2017
Background The incidence of gemcitabine-induced hemolytic uremic syndrome has already been described in adults. Several approaches have been employed in the treatment of gemcitabine-induced hemolytic uremic syndrome with different outcomes.
Ludovica Facchini, Maurizio Lucchesi, Alessia Stival, Rosa Maria Roperto, Francesca Melosi, Marco Materassi, Silvia Farina, Veronica Tintori, Maurizio de Martino, Iacopo Sardi   +9 more
doaj   +1 more source

Complete Dialysis‐Free Recovery From Severe Malaria–Associated Acute Kidney Injury and Multiorgan Failure: A Case Report and Brief Literature Review

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Severe malaria remains a major cause of acute kidney injury and multiorgan failure in endemic regions, often requiring renal replacement therapy. However, access to dialysis is limited in many resource‐constrained settings, making outcomes highly dependent on early diagnosis and effective antimalarial treatment. We report a 32‐year‐old man who
Tamirat Godebo Woyimo, Amare Hailu Ashine, Mohammed Kedir Shukri, Yonas Damtew Bejiga, Ragasa Getachew, Yosef Bekele Bonsa, Rediet Girmaye, Tsion Haile Woldemariam, Adugna Lamessa   +8 more
wiley   +1 more source

Anti factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome [PDF]

, 2007
The atypical form of the kidney disease hemolytic uremic syndrome (aHUS) is associated with defective complement regulation. In addition to mutations in complement regulators, factor H (FH)-specific autoantibodies have been reported for aHUS patients ...
Dahse, H. M., Hoyer, P. F., Józsi, Mihály, Liu, W. S., Strobel, S.   +4 more
core   +1 more source

Factors Governing the Cross-Species Virulence of Shiga Toxin-Producing Escherichia coli

Pathogens
Phage-encoded Shiga toxin (Stx) released by Shiga toxin-producing E. coli (STEC) can kill multiple eukaryotic bacterial predators, including Acanthamoeba castellanii, Tetrahymena thermophila and Caenorhabditis elegans.
Paul Hart, Alexander Bowitch, Alexander Mellmann, Denise M. Ferkey, Gerald B. Koudelka   +4 more
doaj   +1 more source

Shiga Toxin Detection Methods : A Short Review [PDF]

, 2013
The Shiga toxins comprise a family of related protein toxins secreted by certain types of bacteria. Shigella dysenteriae, some strain of Escherichia coli and other bacterias can express toxins which caused serious complication during the infection. Shiga
González-Aguilar, G., Guerrero, Y. Castaño   +1 more
core  

Infection due to Shiga toxin-producing enterohemorrhagic Escherichia coli (EHEC) presenting as ischemic colitis

IDCases, 2019
Infections due to Shiga toxin-producing enterohemorrhagic Escherichia coli (EHEC) are often mild and self-limiting, but more severe cases can develop into hemolytic uremic syndrome (HUS) and hemorrhagic colitis. This case report documents a sporadic case
Camille D. Tanquilut, Chin W. Jung, Allen W. Nelson, Sean K. Lau   +3 more
doaj   +1 more source

Dangerous drug interactions leading to hemolytic uremic syndrome following lung transplantation [PDF]

, 2010
Background To report our experience of a rather uncommon drug interaction, resulting in hemolytic uremic syndrome (HUS). Methods Two consecutive cases of hemolytic uremic syndrome were diagnosed in our service.
Haralabos Parissis, Kate Gould, John Dark   +2 more
core   +2 more sources

Clinical aspects of a nationwide epidemic of severe haemolytic uremic syndrome (HUS) in children [PDF]

, 2011
Background Report a nationwide epidemic of Shiga toxin-producing E. coli (STEC) O103:H25 causing hemolytic uremic syndrome (D+HUS) in children.
Krogvold, Lars, Henrichsen, Thore, Bjerre, Anna, Brackman, Damien, Dollner, Henrik, Gudmundsdottir, Helga, Syversen, Gaute, Aksel Næss, Pål, Jacob Bangstad, Hans   +8 more
core   +1 more source