Results 111 to 120 of about 21,085 (234)

Cerebral Involvement of Hemophagocytic Lymphohistiocytosis in Griscelli Syndrome

, 2019
Type II Griscelli Syndrome (GS) is caused by a mutation in the RAB27A gene and usually manifests with silvery-gray hair, immune deficiency and the development of hemophagocytic lymphohistiocytosis (HLH).
Ersin Töret, Aksoylar, Serap, Oymak, Yeşim, Tuba Hilkay Karapınar, Yılmaz Ay, Ay, Yılmaz, Yeşim Oymak, Toret, Ersin, Serap Aksoylar, Karapınar, Tuba Hilkay, AY, YILMAZ, karapinar, tubahilkay   +11 more
core   +1 more source

Heartland Virus and Hemophagocytic Lymphohistiocytosis in Immunocompromised Patient, Missouri, USA [PDF]

, 2018
Heartland virus is a suspected tickborne pathogen in the United States. We describe a case of hemophagocytic lymphohistiocytosis, then death, in an immunosuppressed elderly man in Missouri, USA, who was infected with Heartland ...
Carlson, Abigail L, Buller, Richard S, Staples, J. Erin, J. Erin Staples, George Turabelidze, Byrnes, Kathleen, Pastula, Daniel M, Jesse Keller, Kuhlmann, F. Matthew, Louis Dehner, Nigar Kirmani, Atis Muehlenbachs, F. Matthew Kuhlmann, Lambert, Amy J, Hess, Brian, Charles S. Eby, Gregory A. Storch, Kathleen Byrnes, Dehner, Louis, Eby, Charles S, Keller, Jesse, Abigail L. Carlson, Brian Hess, Turabelidze, George, Kirmani, Nigar, Daniel M. Pastula, Amy J. Lambert, Muehlenbachs, Atis, Richard S. Buller, Storch, Gregory A   +29 more
core   +1 more source

HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS CASE PRESENTATION

, 2019
Purpose: The purpose of this article is to discuss a case presentation of a rare form of acquired Hemophagocytic Lymphohistiocytosis (HLH) and review the standard of care in addition to current therapeutic options for the disease.
Delaney, Kristen, PA-C, Ginebra, Claudio, RPA-C, Zaslav, Ann-Leslie, PhD, Bonanno, Lenore, PA, MS, DMSc-Fellow, Kiner-Strachan, Bonnie, MD   +4 more
core   +1 more source

Adult cancer-related hemophagocytic lymphohistiocytosis – a challenging diagnosis: a case report

Journal of Medical Case Reports, 2017
Background Adult hemophagocytic lymphohistiocytosis is a secondary immunopathologic phenomenon, mainly secondary to malignancy, infection, or autoimmune disorders.
Michael A. Hust, Boris R. A. Blechacz, Diana L. Bonilla, Naval Daver, Cristhiam M. Rojas-Hernandez   +4 more
doaj   +1 more source

Prognostic Value of Skin Lesion Characteristics in Subcutaneous Panniculitis‐Like T‐Cell Lymphoma: A Retrospective Cohort Study Assessing the Applicability of T Category of the TNM Classification for Primary Cutaneous Lymphomas Other Than Mycosis Fungoides and Sézary Syndrome

International Journal of Dermatology, Volume 65, Issue 11, Page 2307-2314, November 2026.
Subcutaneous panniculitis‐like T‐cell lymphoma. Survival outcomes according to the presence of hemophagocytic lymphohistiocytosis (HLH) and T category. Relapse‐free survival was inferior in patients presenting with generalized (T3) skin lesions. Overall survival was poor in patients with HLH. Relapse‐free survival was also reduced in patients with HLH.
Myoung Eun Choi, Joon Min Jung, Soo Hyun Jeon, Chong Hyun Won, Sung Eun Chang, Mi Woo Lee, Woo Jin Lee   +6 more
wiley   +1 more source

Defective UNC13D Gene-associated Familial Hemophagocytic Lymphohistiocytosis Triggered by Visceral Leishmaniasis: A Diagnostic Challenge

, 2014
Background: Visceral leishmaniasis (VL) triggered genetic hemophagocytic lymphohistiocytosis (HLH) is clinically ...
Azik, Fatih M., Balta, Gunay, Gurgey, Aytemiz   +2 more
core   +1 more source

UNC13D is the predominant causative gene with recurrent splicing mutations in Korean patients with familial hemophagocytic lymphohistiocytosis

Haematologica, 2010
Background Familial hemophagocytic lymphohistiocytosis is a fatal disease characterized by immune dysregulation from defective function of cytotoxic lymphocytes.
Hoi Soo Yoon, Hee-Jin Kim, Keon-Hee Yoo, Ki-Woong Sung, Hong-Hoe Koo, Hyoung Jin Kang, Hee Young Shin, Hyo Seop Ahn, Ji-Yoon Kim, Young-Tak Lim, Keun-Wook Bae, Ki-O Lee, Ji-Sook Shin, Seung-Tae Lee, Hae-Sun Chung, Sun-Hee Kim, Chan-Jeoung Park, Hyun-Sook Chi, Ho-Joon Im, Jong Jin Seo   +19 more
doaj   +1 more source

Incidence, Clinical Characteristics, Management, and Outcomes of Hematologic Immune‐Related Adverse Events Associated With Immune Checkpoint Inhibitors: A Single‐Center Japanese Retrospective Cohort Study

Cancer Medicine, Volume 15, Issue 10, October 2026.
This single‐center retrospective study evaluated hematologic immune‐related adverse events (irAEs) among 3371 patients treated with immune checkpoint inhibitors. Forty patients developed hematologic irAEs (1.2%); 85.0% of events were Grade 3 or higher, and the median time to onset was 12 weeks.
Ryo Yoshimaru, Hirotaka Nakamura, Yong‐Mei Guo, Kensuke Matsuda, Tetsuya Sakai, Yoshitaka Zenke, Kiyotaka Yoh, Kohei Shitara, Nobuaki Matsubara, Kenichi Harano, Hiromichi Nakajima, Nobuyuki Takahashi, Masafumi Ikeda, Takao Fujisawa, Saki Nakamura, Kenta Akie, Masayuki Ito, Masashi Wakabayashi, Junichiro Yuda   +18 more
wiley   +1 more source

Severe Plasmodium vivax Malaria Complicated by Secondary Hemophagocytic Lymphohistiocytosis, Disseminated Intravascular Coagulation, and Acute Pancreatitis: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Plasmodium vivax (P. vivax) malaria, once regarded as a comparatively benign infection, is increasingly recognized as a cause of severe, potentially life‐threatening multisystem disease. Concurrent secondary hemophagocytic lymphohistiocytosis (HLH), disseminated intravascular coagulation (DIC), and acute pancreatitis complicating P.
Tasnim Nafian, Md. Abul Kalam Azad, Khaled Mahbub Murshed, Kazi Ali Aftab, Rubayet Shahriar, Abdullah Al Faisal   +5 more
wiley   +1 more source

Unusual Hemodynamic Presentation of Pediatric Kikuchi‐Fujimoto Disease: Persistent Sinus Bradycardia and Vasopressor‐Dependent Hypotension

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Kikuchi‐Fujimoto disease rarely presents with vasopressor‐dependent hypotension requiring pediatric intensive care despite preserved cardiac function. This case highlights the importance of early excisional lymph node biopsy for timely diagnosis and appropriate management of children with unexplained hemodynamic instability and necrotizing ...
Abdulla Alfraij, Fatma Mothafar, Wasmi Alfadhli, Ali Ashkanani, Lujain A. Kamal, Esmail Redha, Abdulrahman Aldaithan   +6 more
wiley   +1 more source