Results 111 to 120 of about 36,076 (253)

Anemia in Antiretroviral Naïve HIV/AIDS Patients: A Study from Eastern India [PDF]

, 2012
Background: Hematological manifestations are common throughout the course of HIV infection. Impact of anemia is the most significant among them. The present study was undertaken to evaluate the etiologies underlying anemia in HIV/AIDS. Methods This was a
Banerjee, A, Bhattacharyya, M, Ghosh, A, Ghosh, B, Pain, S, Pande, A, Saha, S   +6 more
core   +1 more source

Immune endotypes in tuberculosis: Keys to decoding disease complexity

Journal of Internal Medicine, Volume 299, Issue 6, Page 670-693, June 2026.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor, Julia Guthrie, Lina Davies Forsman, Andrew R. Di Nardo, Susanna Brighenti   +4 more
wiley   +1 more source

Diagnostic biomarkers for adult haemophagocytic lymphohistiocytosis in critically ill patients (HEMICU): a prospective observational study protocol [PDF]

, 2019
INTRODUCTION: Haemophagocytic lymphohistiocytosis (HLH) in adults is characterised by toxic immune activation and a sepsis-like syndrome, leading to high numbers of undiagnosed cases and mortality rates of up to 68%.
Akyüz, Levent, Balzer, Felix, Brunkhorst, Frank M., Haefen, Clarissa von, Keh, Didier, Knaak, Cornelia, Kruppa, Jochen, Kölsch, Uwe, La Rosée, Paul, Lachmann, Gunnar, Lachmann, Nils, Meisel, Christian, Nyvlt, Peter, Paeschke, Nadine, Piper, Sophie K., Schenk, Thomas, Schuster, Friederike S., Spies, Claudia, Unterwalder, Nadine, Volk, Hans-Dieter, Vorderwülbecke, Gerald   +20 more
core   +1 more source

Relative Exchangeable and Exchangeable Copper: Emerging New Biomarkers for Diagnosis and Therapy Monitoring in Wilson's Disease

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Wilson's disease (WD) is a genetic disorder of copper metabolism in which early diagnosis remains challenging, particularly in acute liver failure (ALF). Relative exchangeable copper (REC) and exchangeable copper (CuEXC) are emerging biomarkers for diagnosis and monitoring, but data from larger cohorts are limited.
Sebastian Köhrer, Antoan Rusev, Holger Zimmer, Silke Wolf, Jessica Langel, Andrea Langel, Thomas Longerich, Patrick Michl, Moritz Niesert, Alexander Fichtner, Isabelle Mohr   +10 more
wiley   +1 more source

Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in a ten-year-old girl accompanied by posterior reversible encephalopathy syndrome and disseminated herpes simplex virus infection [PDF]

, 2015
　可逆性後頭葉白質脳症は通常臨床的には頭痛・痙攣・視覚障害等の神経症状で発症するしばしば認める疾患である．一方，播種性ヘルペス感染症は免疫不全患者で認める感染症である．今回我々は，EBウイルス関連血球貪食症候群に対するエトポシド・プレドニゾロン・シクロスポリンを用いた多剤併用化学療法中に，シクロスポリン関連可逆性後頭葉白質脳症と播種性ヘルペス感染症と診断された10歳女児を経験したので報告する．EBウイルス関連血球貪食症候群に対する併用療法は当初有効であったが ...
板倉 隆太, 森脇 浩一, 浅野 祥孝, 田村 正徳, 荒川 歩, 難波 文彦   +5 more
core  

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real‐world study

International Journal of Cancer, Volume 158, Issue 10, Page 2674-2683, 15 May 2026.
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang, Jing‐jing Sun, Zhi Wan, Xiao‐yu Jing, Xia Guo, Ju Gao   +5 more
wiley   +1 more source

Défaut d’exocytose des granules lytiques : Plusieurs causes, un même effet [PDF]

, 2006
Une réponse immune exagérée, incontrôlée et le plus souvent fatale, connue sous le nom de syndrome hémophagocytaire (SH), est associée à un défaut de la fonction cytotoxique des lymphocytes T et natural killer (NK).
de Saint Basile, Geneviève, Fischer, Alain, Le Deist, Françoise, Ménager, Mickaël, Ménasché, Gaël   +4 more
core  

Fixed‐Duration Subcutaneous Mosunetuzumab in Relapsed/Refractory Follicular Lymphoma: Pivotal Phase 2 Primary Analysis

American Journal of Hematology, Volume 101, Issue 5, Page 986-997, May 2026.
ABSTRACT Mosunetuzumab is approved as an intravenous (IV) formulation for relapsed/refractory (R/R) follicular lymphoma (FL) after ≥ 2 prior therapies. A subcutaneous (SC) formulation, aiming to improve patient safety and convenience, has been developed.
Nancy L. Bartlett, Laurie H. Sehn, Sarit Assouline, Pratyush Giri, John Kuruvilla, Stephen J. Schuster, Sung‐Soo Yoon, Keith Fay, Georg Hess, Martin Dreyling, Norma C. Gutierrez, Eva Cybulski, Fidelis Sabalvaro, Elicia Penuel, Vanda Teodoro, Samuel Tracy, Denison Kuruvilla, Joseph Chen, Volker Wiebking, Michael C. Wei, L. Elizabeth Budde   +20 more
wiley   +1 more source

Macrophage Activation Syndrome [PDF]

, 2015
Macrophage activation syndrome (MAS) is a potentially life-threatening complication of rheumatic diseases such as systemic juvenile idiopathic arthritis (sJIA) and systemic lupus erythematosus.
Clarke, Sarah L N, Ramanan, Athimalaipet V, Sen, Ethan S   +2 more
core   +2 more sources

An Unusual Case of Classic Hodgkin Lymphoma With Strong Expression of B‐Cell Markers

International Journal of Laboratory Hematology, EarlyView.
Christopher Liwski, Sorin Selegean, Allam Shawwa, David M. Conrad   +3 more
wiley   +1 more source