Journal of Medical Case ReportsBackground Hemophagocytic lymphohistiocytosis is rare and does not have any distinct clinical features or laboratory abnormalities, whereby a high index of suspicion is required for diagnosis.
Kar Ven Cavan Chow +3 more
doaj +1 more source
Secondary hemophagocytic lymphohistiocytosis in a child with Leptospira infection: A case report
The Turkish Journal of Pediatrics, 2018 Leptospirosis caused by spirochetes of the genus Leptospira in most patients result in very mild illness without jaundice. However, a small portion of patients develop various complications due to the involvement of multiple organ systems ...
Dragana Jevtic +5 more
doaj +1 more source
Genetic dissection of NK cell responses [PDF]
, 2013 The association of Natural Killer (NK) cell deficiencies with disease susceptibility has established a central role for NK cells in host defence. In this context, genetic approaches have been pivotal in elucidating and characterizing the molecular ...
Jennifer Marton +3 more
core +2 more sources
Secondary Dengue Infection Complicated by Hemophagocytic Lymphohistiocytosis: A Case Report
Case Reports in Infectious DiseasesHemophagocytic lymphohistiocytosis is a fatal hyperinflammatory disorder in which CD8+ cytotoxic T-cells, natural killer cells, and macrophages destroy hematopoietic cells and vital organs. Viral infections, such as Epstein–Barr virus, are known to cause
Dominique D. Davis +3 more
doaj +1 more source
Journal of Medical Case Reports, 2017 Background Total colonic and small bowel aganglionosis is a rare condition typically requiring intestinal transplant for long-term survival. There have not been any previously reported cases of near total intestinal aganglionosis complicated by concerns ...
Brittany Badal +2 more
doaj +1 more source
Hemophagocytic Lymphohistiocytosis Complicating Myelodysplasia [PDF]
, 2014 We describe a 62-year-old patient with a 4-year history of myelodysplasia who later developed striking features that included massive splenomegaly, rapidly evolving visual loss and a sensorimotor polyneuropathy.
Belleyo-Belkasem, Carima +4 more
core +2 more sources
Adult cancer-related hemophagocytic lymphohistiocytosis – a challenging diagnosis: a case report
Journal of Medical Case Reports, 2017 Background Adult hemophagocytic lymphohistiocytosis is a secondary immunopathologic phenomenon, mainly secondary to malignancy, infection, or autoimmune disorders.
Michael A. Hust +4 more
doaj +1 more source
Fulminant systemic capillary leak syndrome due to C1 inhibitor deficiency complicating acute dermatomyositis: a case report [PDF]
, 2014 INTRODUCTION: Dermatomyositis is a chronic inflammatory disorder characterized by muscular and dermatologic symptoms with variable internal organ involvement.
Andreas Brunauer +5 more
core +1 more source
Clonal origin of Epstein-Barr virus-infected T/NK-cell subpopulations in chronic active Epstein-Barr virus infection [PDF]
, 2010 Clonal expansion of Epstein-Barr virus (EBV) infected B-cells occasionally occurs in immunocompromized subjects. EBV-infected T/natural killer (NK)-cells proliferate in patients with chronic active EBV infection (CAEBV) that is a rare mononucleosis ...
Goichi Toshimoto +10 more
core +1 more source
A Case of Refractory Langerhans Cell Histiocytosis Complicated with Hemophagocytic Lymphohistiocytosis Rescued by Cord Blood Transplantation with Reduced-intensity Conditioning [PDF]
, 2017 We diagnosed a female infant with Langerhans cell histiocytosis (LCH) who was refractory to conventional chemotherapy. She showed refractory inflammation that was complicated with hemophagocytic lymphohistiocytosis (HLH) during LCH chemotherapy ...
Kanamitsu, Kiichiro +4 more
core +1 more source