Results 41 to 50 of about 16,441 (215)

SÍNDROME HEMOFAGOCÍTICO INDUCIDO POR HISTOPLASMA

Revistas Argentina de Medicina, 2018
La incidencia de histoplasmosis se ha estimado en un 5% en pacientes con virus de inmunodeficiencia humana (VIH) y es la tercera micosis potencialmente fatal.
Lourdes Vera, Nancy Camo, Silvina Daquila, Grisel Garro, Carla Giuliano   +4 more
doaj   +2 more sources

Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in a postpartum patient with preeclampsia: a case report

AJOG Global Reports, 2021
Hemophagocytic lymphohystiocytosis is an extremely life-threatening immune deregulatory syndrome. It is characterized by pathologic activation of immune cells, leading to excessive cytokine production, multiorgan failure, and potentially, death.
Bruce Lee, MD, Peter Kouides, MD, Stephanie Bousquet, MD, Paul Cabral, MD   +3 more
doaj   +1 more source

Hemophagocytic Syndrome Associated with Herpes Virus 8 and Multicentric Castleman Disease in A HIV Negative Patient

Journal of Microbiology and Infectious Diseases, 2017
The Hemophagocytic syndrome (HS) is a very rare and aggressive disorder characterized by strong immunological activation of the mononuclear phagocyte system sometimes triggered by viral infections such as Epstein-Barr Virus.
Arturo Gonzalez Raya, Eva Martin Salido, Miguel F Cantero Sanchez, Gonzalo Callejón Martín, María L Hortas Nieto   +4 more
doaj   +1 more source

Case report: Drug reaction with eosinophilia and systemic symptoms (DRESS)-induced hemophagocytic disorder

Frontiers in Pharmacology, 2022
Hemophagocytic disorders are severe and life-threatening conditions that can be genetic in origin [i.e., primary hemophagocytic lymphohistiocytosis (HLH)] or result from infections (i.e., secondary hemophagocytic lymphohistiocytosis), rheumatologic ...
Eliza I. Pope, Hosanna Au, Hosanna Au, Deborah M. Levy, Deborah M. Levy, Ruud H. J. Verstegen, Ruud H. J. Verstegen, Ruud H. J. Verstegen   +7 more
doaj   +1 more source

Hemophagocytic Syndrome Which Developed During Treatment of Community Acquired Pneumonia: A Case Report

, 2013
: Hemophagocytic syndrome (HLH), which occurs due to over activation and proliferation of the T-cells and macrophages resulting in massive hypercytokinemia, is a life threatening condition accompanied by systemic inflamatory diseases.
Arzu Gebeşçe, Esengül Keleş, Hamza Yazgan   +2 more
core   +1 more source

The IL‐10/IL‐6 Ratio and the Risk Score: Two Cytokines‐Based Predictors for Malignancy‐Associated Hemophagocytic Lymphohistiocytosis in Adults (M‐HLHa)

American Journal of Hematology, EarlyView.
ABSTRACT The predictive value of cytokines (CK) for malignancy‐associated adult hemophagocytic lymphohistiocytosis (M‐HLHa) remains uncertain. We evaluated a cytokine‐based Risk Score (RS) and the IL‐10/IL‐6 Ratio to predict M‐HLHa. Adult patients (n = 112) from the French HLH cohort (NCT02113917) with complete data for nine key HLH related CK measured
Coralie Bloch, Stephanie Chhun, Nanthara Sritharan, Marine Gil, Raphael Lhote, Marouane Boubaya, Olivier Lambotte, David Launay, Claire Larroche, Estibaliz Lazaro, Francois Liffermann, Marc Michel, Jean‐Marie Michot, Pierre Morel, Louis Terriou, Geoffrey Urbansk, Jean‐Francois Viallard, Morgane Cheminant, Felipe Suarez, Yves Lepelletier, Geneviève de Saint Basile, Olivier Hermine, the French HLH Study Group, Coralie Bloch, Jean Philippe Jais, Francois Liffermann, Pierre Morel, Morgane Cheminant, Felipe Suarez, Olivier Hermine, Fabrice Bonnet, Pascal Godemer, Damaj Gandhi, Olivier Fain, Olivier Lambotte, David Launay, Louis Terriou, Claire Larroche, Estibaliz Lazaro, Jean‐Francois Viallard, Francois Liffermann, Olivier Lortholary, Marc Michel, Jean‐Marie Michot, Pierre Morel, Frederic Pene, Antoinette Perlat, Geoffrey Urbanski   +47 more
wiley   +1 more source

Atypical Clinical Course of Griscelli Syndrome Type 2 With Primarily Neurologic Presentation and Adult‐Onset in a 46‐Year‐Old Male

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi, Michael Kutsche, Helena Lichtenfeld, Fanny Kortüm, Angela Abicht, Laura Herrmann, Theresia Herget   +6 more
wiley   +1 more source

Fulminant hemophagocytic lymphohistiocytosis induced by pandemic A (H1N1) influenza: a case report

Journal of Medical Case Reports, 2011
Introduction Hemophagocytic lymphohistiocytosis induced by viral diseases is a well recognized entity. Severe forms of H5N1 influenza are known to be associated with symptoms very similar to a reactive hemophagocytic syndrome.
Wacrenier Agnès, Guerry Mary-Jane, Cornelius Aurélie, Willekens Christophe, Fourrier François   +4 more
doaj   +1 more source

A Case of Multiple Mitochondrial Dysfunctions Syndrome 1 and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple mitochondrial dysfunctions syndrome 1 (MMDS1, MIM #605711) due to NFU1 gene defects is an ultra‐rare autosomal recessive inborn error of metabolism associated with reduced function of NFU1 iron–sulfur cluster (ISC) scaffold protein.
Charles R. DiFalco, Aaron Williams, Claudia Soler‐Alfonso, Emily Waskow, Elizabeth Mizerik, Fernando Scaglia, Chaya N. Murali   +6 more
wiley   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source