Results 101 to 110 of about 69,645 (303)

Hemophilia is associated with accelerated biological aging

Haematologica
Hemophilia is a rare X-linked bleeding disorder caused by mutations in the F8 or F9 gene (hemophilia A or B), leading to deficient factor VIII or IX proteins, respectively.
Marina Trappl, Rafaela Vostatek, Manuel Salzmann, Daniel Kraemmer, Johanna Gebhart, Philipp Hohensinner, Ingrid Pabinger, Cihan Ay   +7 more
doaj   +1 more source

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

Symposium: What is Hemophilia?: Introduction [PDF]

, 1954
William Dameshek
openalex   +1 more source

A Randomized Trial of Factor VIII and Neutralizing Antibodies in Hemophilia A.

New England Journal of Medicine, 2016
BACKGROUND The development of neutralizing anti-factor VIII alloantibodies (inhibitors) in patients with severe hemophilia A may depend on the concentrate used for replacement therapy.
F. Peyvandi, P. Mannucci, I. Garagiola, A. El‐Beshlawy, M. Elalfy, V. Ramanan, P. Eshghi, S. Hanagavadi, R. Varadarajan, M. Karimi, M. Manglani, C. Ross, G. Young, T. Seth, Shashikant Apte, D. Nayak, E. Santagostino, M. Mancuso, Adriana C. Sandoval Gonzalez, J. Mahlangu, Santiago Bonanad Boix, M. Cerqueira, N. Ewing, C. Male, T. Owaidah, Veronica Soto Arellano, N. Kobrinsky, S. Majumdar, R. Perez Garrido, A. Sachdeva, M. Simpson, Mathew Thomas, E. Zanon, B. Antmen, K. Kavaklı, M. Manco‐Johnson, Monica Martinez, E. Marzouka, M. Mazzucconi, D. Neme, Ángeles Palomo Bravo, R. Paredes Aguilera, A. Prezotti, K. Schmitt, B. Wicklund, B. Zulfikar, F. Rosendaal   +46 more
semanticscholar   +1 more source

Physical Activity Awareness and Understanding of Treatment Protection Among People With Haemophilia and Their Caregivers in Central Europe

Haemophilia, EarlyView.
ABSTRACT Background Physical activity is now considered generally beneficial for persons with haemophilia (PWH). However, the specific type and extent of activity and its impact on quality of life (QoL) and bleed protection during exercise is under‐researched.
Angelika Batorova, Atanas Banchev, Ana Boban, Brigitte Brand, Melen Brinza, Barbara Faganel Kotnik, Csongor Kiss, Gediminas Puras, Jan Rajnoch, Ester Zapotocka   +9 more
wiley   +1 more source

The frequency of joint hemorrhages and procedures in nonsevere hemophilia A vs B

Blood Advances, 2018
: Data are needed on minimal factor activity (FA) levels required to prevent bleeding in hemophilia. We aimed to evaluate associations between hemophilia type and FA level and joint bleeding and orthopedic procedures using longitudinal data.
J. Michael Soucie, Paul E. Monahan, Roshni Kulkarni, Barbara A. Konkle, Marshall A. Mazepa   +4 more
doaj  

Identification and Genetic Analysis of a Factor IX Gene Intron 3 Mutation in a Hemophilia B Pedigree in China

Turkish Journal of Hematology, 2014
OBJECTIVE: Hemophilia B is caused by coagulation defects in the factor IX gene located in Xq27.1 on the X chromosome. A wide range of mutations, showing extensive molecular heterogeneity, have been described in hemophilia B patients.
Dong Hua Cao, Xiao Li Liu, Kai Mu, Xiang Wei Ma, Jing Li Sun, Xiao Zhong Bai, Chang Kun Lin, Chun Lian Jin   +7 more
doaj   +1 more source

Plasma Transfusions in Hemophilia [PDF]

, 1952
S. Van Creveld, M.M.P. Paulssen
openalex   +1 more source

Real‐World Unmet Needs of Patients With Haemophilia A and Haemophilia B With or Without Inhibitors: End‐of‐Study Results From the explorer6 Non‐Interventional Study

Haemophilia, EarlyView.
ABSTRACT Introduction Haemophilia is associated with high disease and treatment burdens. Prospective evaluation of data from patients with haemophilia helps understand and define unmet needs, optimise treatment and improve healthcare outcomes. Aim To present end‐of‐study data from explorer6 (NCT03741881), a prospective, non‐interventional study across ...
Allison P. Wheeler, Aby Abraham, Chris Barnes, Renée Brown Frandsen, Roseline d'Oiron, Hermann Eichler, Kingsley Hampton, Francisco José López‐Jaime, Chuhl Joo Lyu, Camila Martins Mazini Tavares, Keiji Nogami, Christopher Sutton, Jerzy Windyga, Bulent Zulfikar, Giancarlo Castaman   +14 more
wiley   +1 more source

Hemoaction game: an educational step to improve hemophilia children and nurses self-efficacy

Journal of Advances in Medical Education and Professionalism, 2016
As hemophilia is a chronic bleeding disease and can interfere with daily performance of children, these children require continuous training to prevent bleeding and take timely action (1).
NOOASHIN BEHESHTIPOOR, SHIRIN GHANAVATI, MITRA EDRAKI, MEHRAN KARIMI, SEZANEH HAGHPANAH   +4 more
doaj