Results 21 to 30 of about 48,129 (210)

Clinical, instrumental, serological and histological findings suggest that hemophilia B may be less severe than hemophilia A

Haematologica, 2016
Recent evidence suggests that patients with severe hemophilia B may have a less severe disease compared to severe hemophilia A. To investigate clinical, radiological, laboratory and histological differences in the arthropathy of severe hemophilia A and ...
Daniela Melchiorre, Silvia Linari, Mirko Manetti, Eloisa Romano, Francesco Sofi, Marco Matucci-Cerinic, Christian Carulli, Massimo Innocenti, Lidia Ibba-Manneschi, Giancarlo Castaman   +9 more
doaj   +1 more source

Establishment of Care System for Hemophilia in China: Current Status and Future Prospect

罕见病研究, 2022
Hemophilia is a X-linked recessive hereditary bleeding disorders. The patients need to receive replacement treatment with coagulation factors in their whole lives.
YANG Renchi
doaj   +1 more source

Hemophilia a genetic disorder: diagnosis, treatment and prognosis [PDF]

, 2016
Hemophilia a genetic disorder with patient’s inability to stop bleeding. There are two main types of hemophilia, hemophiliaA due to not enough clotting factor VIII and hemophilia B due to not enough factor IX,and acquired hemophilia A(AHA) caused by ...
AM Sharifa, Murtaza Mustafa, Ell. Illzam, Firdaus Mohd Hayati, Nornazirah Azizan, Ay Moktar   +5 more
core   +2 more sources

Thromboelastography in pre-surgery monitoring in Hemophilia A with high inhibitor titer: case report and literature review

Romanian Journal of Laboratory Medicine, 2020
The development of factor VIII inhibitors (allo-antibodies) continues to be a major complication in the management of severe forms of hemophilia A, especially as far as treatment and treatment response monitoring is concerned.
Melen Brinza, Uscatescu Valentina, Gheorghe Georgiana, Chiriac Elisabeta, Ciobanu Claudia, Orban Horia, Coriu Daniel   +6 more
doaj   +1 more source

Porcine model of hemophilia A. [PDF]

PLoS ONE, 2012
Hemophilia A is a common X chromosome-linked genetic bleeding disorder caused by abnormalities in the coagulation factor VIII gene (F8). Hemophilia A patients suffer from a bleeding diathesis, such as life-threatening bleeding in the brain and harmful ...
Yuji Kashiwakura, Jun Mimuro, Akira Onishi, Masaki Iwamoto, Seiji Madoiwa, Daiichiro Fuchimoto, Shunichi Suzuki, Misae Suzuki, Shoichiro Sembon, Akira Ishiwata, Atsushi Yasumoto, Asuka Sakata, Tsukasa Ohmori, Michiko Hashimoto, Satoko Yazaki, Yoichi Sakata   +15 more
doaj   +1 more source

Effects of different storage temperatures and durations on the activity of coagulation factor Ⅷ and Ⅸ in whole blood

Zhongguo shuxue zazhi
[Objective] To investigate the effects of different storage temperatures and durations on the activities of coagulation factor Ⅷ (Factor Ⅷ, FⅧ) and coagulation factor Ⅸ (Factor Ⅸ, FⅨ) after whole blood collection, so as to provide data support for the ...
WANG Hehe, WANG Tiantian, WANG Jie, QIAO Cuicui, LIU Wei, ZHANG Xueqin, CHENG Yan, FANG Yunhai, ZHANG Xinsheng   +8 more
doaj   +1 more source

Multiple criteria decision analysis for therapeutic innovations in a hemophilia care center: A pilot study of the organizational impact of innovation in hemophilia care management

, 2022
BACKGROUND: Several innovative drugs liable to lead to changes in healthcare organization are or soon will be available for the management of hemophilia.
Beny, Karen, Dubromel, Amélie, Gay, Valérie, Carrouel, Florence, du Sartz de Vigneulles, Benjamin, Negrier, Claude, Dussart, Claude   +6 more
core   +1 more source

Retrospective analysis of clinical data from 171 low-income patients with hemophilia in Shandong Province

Scientific Reports
To enhance attention on low-income patients with hemophilia, it is essential to urge governments and coagulation factor manufacturers to increase their investment in hemophilia care.
Jie Wang, Yan Cheng, Yunhai Fang, Cuicui Qiao, Tiantian Wang, Hehe Wang, Xueqin Zhang, Qiang Li   +7 more
doaj   +1 more source

Correlation between APTT mixing test results and inhibitor titers in patients with hemophilia A inhibitor

Zhongguo shuxue zazhi
[Objective] To study the correlation between activated partial thromboplastin time (APTT) mixing test results and the inhibitor titers in hemophilia A inhibitor-positive patients.
WANG Tiantian, CHENG Yan, WANG Hehe, QIAO Cuicui, WANG Jie, ZHONG Guangshang, WANG Xiyuan, ZHANG Xueqin, FANG Yunhai   +8 more
doaj   +1 more source

Recurrent bleeding after rubber band ligation diagnosed as mild hemophilia B: a case report and literature review

BMC Surgery, 2022
Background Hemophilia is a recessive hemorrhagic disease relevant to X chromosome. In mild hemophilia cases, spontaneous bleeding is rare and the blood clotting function is normal, but severe bleeding may occur after trauma or surgery.
Xiaoying Jiang, Min Xu, Yaqing Ding, Yongqing Cao, Yibin Pan   +4 more
doaj   +1 more source