Results 171 to 180 of about 22,643,381 (355)

Subjective Physical Performance and Its Determinants in Patients With Haemophilia

Haemophilia, EarlyView.
ABSTRACT Introduction Physical functioning is compromised in patients with haemophilia (PwH). However, factors negatively influencing subjective physical performance (SPP) remain underexplored. Hence, this study aimed to compare the SPP of PwH with healthy controls (CON), to differentiate them based on disease‐specific, person‐related, and arthropathy ...
Alexander Schmidt, Fabian Tomschi, Pia Möllers, Marius Brühl, Sylvia von Mackensen, Andreas C. Strauss, Heinrich Richter, Johannes Oldenburg, Thomas Hilberg   +8 more
wiley   +1 more source

Physical Activity Awareness and Understanding of Treatment Protection Among People With Haemophilia and Their Caregivers in Central Europe

Haemophilia, EarlyView.
ABSTRACT Background Physical activity is now considered generally beneficial for persons with haemophilia (PWH). However, the specific type and extent of activity and its impact on quality of life (QoL) and bleed protection during exercise is under‐researched.
Angelika Batorova, Atanas Banchev, Ana Boban, Brigitte Brand, Melen Brinza, Barbara Faganel Kotnik, Csongor Kiss, Gediminas Puras, Jan Rajnoch, Ester Zapotocka   +9 more
wiley   +1 more source

Survival of 125iodine-labeled Factor VIII in normals and patients with classic hemophilia. Observations on the heterogeneity of human Factor VIII. [PDF]

, 1978
J Over, J J Sixma, M H M Doucet-De Bruïne, M C Trieschnigg, Riek A. A. Vlooswijk, Nel H. BEESER‐VISSER, Bonno N. Bouma   +6 more
openalex   +1 more source

Trends in Treatment of Severe Haemophilia and Impact on Inhibitor Assessment by the EUHASS Registry

Haemophilia, EarlyView.
ABSTRACT Background The last 15 years have seen new extended half‐life (EHL) recombinant FVIII/IX concentrates and nonreplacement therapy for haemophilia A (emicizumab) introduced in Europe. These changes affect FVIII/IX exposure in previously untreated patients (PUPs) and previously treated patients (PTPs) with severe haemophilia A and B (SHA and SHB)
Kathelijn Fischer, Riitta Lassila, Flora Peyvandi, Alex Gatt, Samantha C. Gouw, Rob Hollingsworth, Thierry Lambert, Radoslaw Kaczmarek, Diana Carbonero, Michael Makris, the EUHASS participants   +10 more
wiley   +1 more source

Association of inferior vena cava filter placement for venous thromboembolic disease and a contraindication to anticoagulation with 30-day mortality [PDF]

, 2018
Importance: Despite the absence of data from randomized clinical trials, professional societies recommend inferior vena cava (IVC) filters for patients with venous thromboembolic disease (VTE) and a contraindication to anticoagulation therapy.
Brown, David L, Novak, Eric, Saeed, Mohammed J, Turner, Tyson E   +3 more
core   +1 more source

Evaluation of Safety and Efficacy of Emicizumab Prophylaxis in Egyptian Pediatric Patients with Hemophilia A

Turkish Journal of Hematology
Objective: Hemophilia A (HA) is a hereditary X-linked bleeding disorder secondary to deficiency of the clotting factor VIII (FVIII). Emicizumab is a monoclonal antibody that replaces the function of the activated FVIII and prevents bleeding in HA ...
Tamer Hassan, Marwa Zakaria, Manar Fathy, Ahmed Farag, Eman Abdelhady, Dalia Gameil, Mustafa Abu Hashem   +6 more
doaj   +1 more source

Expression and Linkage of Genes for X-linked Hemophilias A and B in the Dog [PDF]

, 1973
K. M. Brinkhous, Peter D. Davis, John B. Graham, W. Jean Dodds   +3 more
openalex   +1 more source

Multimodal Exercise Program of Balance and Strength Improves Dynamic Balance, Strength and Functionality and Decreases the Risk of Falls in Adults With Haemophilia

Haemophilia, EarlyView.
ABSTRACT Introduction Haemophilia is a hereditary bleeding disorder that leads to joint damage and musculoskeletal impairments, affects balance and increases the risk of falls. Although exercise is beneficial, little is known about the clinical effects of programmes that focus on balance and proprioception in people with haemophilia (PwH).
Ana Chimeno‐Hernández, Sofía Pérez‐Alenda, Carlos Cruz‐Montecinos, Juan. J. Carrasco, Marta Aguilar‐Rodriguez   +4 more
wiley   +1 more source

Changes over the last two decades in Hemophilia A and B management in a Tertiary Care Pediatric Centre

Clinical Epidemiology and Global Health
Objective: The treatment of Hemophilia A and B has significantly evolved. Study design: we conducted a retrospective, observational study among patients with HA and HB managed in a Pediatric Hematology and Oncology Unit for almost 22 years for a total of
M.P. Esposto, E. Bonetti, R. Balter, V. Pezzella, A. Zaccaron, V. Vitale, G. Caddeo, M. Chinello, G. Tridello, G. Poli, S. Cesaro   +10 more
doaj  

Rational design of FVIII sialylated peptides to target Siglec-3 and Siglec-9 and improve peptide formulations for reverse vaccines

Frontiers in Bioengineering and Biotechnology
Reverse vaccine formulations have shown their potential for the treatment of allergies and other autoimmune diseases by the design of antigens that modify dendritic cell function towards tolerogenic responses.
Eleonora Nardini, Eleonora Nardini, Brigitte-Carole Keumatio Doungstop, Brigitte-Carole Keumatio Doungstop, Tania Gerpe-Amor, Aram M. de Haas, Aram M. de Haas, Mike de Kok, Evert Peterse, Evert Peterse, Hakan Kalay, Rui-Jún E. Li, Fabrizio Chiodo, Fabrizio Chiodo, Fabrizio Chiodo, Alba Silipo, Jan Voorberg, Yvette van Kooyk, Yvette van Kooyk, Yvette van Kooyk   +19 more
doaj   +1 more source