Results 191 to 200 of about 82,032 (316)

Optimizing Oligonucleotide Therapeutics: A Model‐Informed Drug Development Perspective

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Oligonucleotide therapies have emerged as a powerful therapeutic class, providing novel solutions for diverse diseases through antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), and aptamers that specifically target and modulate gene expression or protein function. However, oligonucleotide development faces distinct challenges,
Ye Yuan, Vishnu Sharma, Venkatesh Atul Bhattaram, Xiaolei Pan, Justin Earp, Yun Wang, Jiang Liu, Hao Zhu   +7 more
wiley   +1 more source

Delayed diagnosis of hemophilia A presenting as chronic joint swelling: a case report. [PDF]

Front Pediatr
Yu C, Luo C, Yang L, Chen L.
europepmc   +1 more source

A report of clinicians’ attitude survey of acquired hemophilia A in daily clinical practice

, 2017
Yoshinobu Seki, Ouki Nagano, Hiroki Nemoto, Takuya Kasami, Syukuko Miyakoshi   +4 more
openalex   +2 more sources

Post-operative Bleeding due to Acquired Hemophilia Successfully Treated with Recombinant Factor VIIa: Case Report [PDF]

, 2009
Naria Lee, Seong Hoon Yoon, Won Lim, Mi‐Hyun Kim, Hyo Jeong Kim, Seon Kyeong Kim, Jin Sup Park, Young Mi Seol, Moo Kon Song, Young Jin Choi, Joo Seop Chung, Goon Jae Cho   +11 more
openalex   +1 more source

Management of neonatal massive hemorrhage: A narrative review

Transfusion, EarlyView.
Cheryl S. L. Chooi, Mary Claire Simmonds, Laura Fisher, Tara Crawford, Michael J. Stark, Scott Morris, Marcus Brecht, Fiona Taverner   +7 more
wiley   +1 more source

Efficacy and Safety of Prophylaxis With a Plasma‐Derived von Willebrand Factor/Factor VIII Concentrate (Wilate) in Patients With Type 3 von Willebrand Disease—A WIL‐31 Study Sub‐Analysis

European Journal of Haematology, Volume 116, Issue 5, Page 674-681, May 2026.
ABSTRACT Objectives The WIL‐31 study demonstrated efficacy and safety of prophylaxis with the plasma‐derived von Willebrand factor/factor VIII concentrate wilate in von Willebrand disease (VWD) of all types and was the only prospective study with an on‐demand run‐in study as an intra‐individual comparator.
Claudia Djambas Khayat, Leonid Dubey, Adlette Inati, Toshko Lissitchkov, Dzmitry Novik, Elina Peteva, Robert F. Sidonio Jr, Ali T. Taher, Kateryna V. Vilchevska, Vladimir Vdovin, Ana Boban   +10 more
wiley   +1 more source

The relationship between joint health, kinesiophobia, physical activity level, and functional capacity in hemophilia patients: a case-control study. [PDF]

Acta Orthop Traumatol Turc
Özdemir H, Tuna F, Sezer T, Comert M, Demirci U, Gulsum Umit E, Demirbağ Kabayel D, Demir AM.   +7 more
europepmc   +1 more source

The Trust‐Link Relational Transition Model: A Unitary Caring Framework for Youth With HIV Transitioning to Adult Healthcare

Journal of Advanced Nursing, Volume 82, Issue 5, Page 5479-5492, May 2026.
ABSTRACT Aims To develop a conceptual model integrating Robinson's Theory of Trust and Watson's Caritas Processes to guide trust‐building approaches and caring practices that support adolescents and young adults with HIV during the healthcare transition from paediatric to adult care.
Emily Anne Barr, Sara Horton‐Deutsch
wiley   +1 more source

Monochorionic diamniotic twin brothers with severe hemophilia A: a case report. [PDF]

Front Pediatr
Riboldi L, Coscia A, Peila C.
europepmc   +1 more source

Personalization of hemophilia treatment by pharmacokinetic-guided dosing [PDF]

, 2020
Tim Preijers
openalex