Results 201 to 210 of about 118,583,499 (297)

A next-generation FVIIIa mimetic in the making. [PDF]

Blood Adv
Srivastava A.
europepmc   +1 more source

Teaching Cell and Gene Therapy in Genetic Counseling Programs: Survey Findings and Suggested Practical Resources for Integration

Journal of Genetic Counseling, Volume 35, Issue 5, October 2026.
ABSTRACT As cell and gene therapies (CGTs) advance through clinical trials into clinical practice, it becomes increasingly important for genetic counselors (GCs) to understand these therapeutics to discuss them with patients. Despite the apparent need for GCs to obtain CGT‐related education, little is known about the training GCs receive on CGT topics ...
Mariel Sebby, Lily McConachie, Leah Wetherill, Paula Delk, Emily L. Hopewell   +4 more
wiley   +1 more source

Managing Pediatric Acquired Hemophilia A When Guideline-Recommended Bypassing Agents Are Unavailable: A Case Report. [PDF]

J Clin Med
Zhang L, Guo XL, Xiao JW, Guo YX.
europepmc   +1 more source

Red lines and green lights: Gene therapy for inherited erythroid disorders beyond the haemoglobinopathies

British Journal of Haematology, Volume 209, Issue 4, Page 1469-1481, October 2026.
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi, Nandakumar Natarajan, Kathryn E. Dickerson, Richard A. Voit   +3 more
wiley   +1 more source

Coronary bypass for acute coronary syndrome in severe hemophilia A. [PDF]

Turk Gogus Kalp Damar Cerrahisi Derg
Tanrıverdi H, Aşık R, Çınar OE, Ediboğlu ED.   +3 more
europepmc   +1 more source

Investigating the Distribution: Signal, Noise, and the Resolution Toolkit in Evidence‐Based Medicine

Journal of Evaluation in Clinical Practice, Volume 32, Issue 7, October 2026.
ABSTRACT Rationale, Aims and Objectives Evidence‐based medicine (EBM) manages observational noise but lacks an explicit framework for taxonomic blur: treatment‐relevant variation generated when syndromic populations mix patients differing in mechanism or treatment responsiveness. Patients present with syndromes, not resolved pathophysiological classes.
Frederick Arthur
wiley   +1 more source

Evaluation of the completeness of a medical record dataset linked to administrative claims through tokenization in patients with Hemophilia B. [PDF]

PLoS One
Kane AS, Stan DM, Jeng D, Chen Y.
europepmc   +1 more source

An Automated Microfluidic System for Haemostasis Assessment in Cirrhosis With Thrombocytopenia

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background & Aims Conventional laboratory tests do not capture platelet–vessel wall interactions (primary haemostasis) occurring in vivo, limiting guidance before invasive procedures. This is relevant in patients with thrombocytopenia, hallmark of advanced cirrhosis. Microfluidic assays may overcome these limitations.
Niccolò Bitto, Giulia Tosetti, Armando Tripodi, Anna Lecchi, Silvia La Marca, Lidia Padovan, Erica Scalambrino, Marigrazia Clerici, Camilla Caputo, Martina Lucà, Massimo Primignani, Anna Ludovica Fracanzani, Pietro Lampertico, Flora Peyvandi, Vincenzo La Mura   +14 more
wiley   +1 more source

Bleeding events in people with hemophilia B on prophylactic factor IX treatment: a systematic review and meta-analysis. [PDF]

Res Pract Thromb Haemost
Lindsley K, Nevo A, Colavecchia C, Wilcox LJ, Patel P, Estevez C, Khanji C, Uyei J, Pipe SW, Young G.   +9 more
europepmc   +1 more source

Cryoprecipitate utilisation, shortages and institutional policies in the United States: A survey of practices and policies

Transfusion Medicine, Volume 36, Issue 5, Page 503-510, October 2026.
Abstract Background Since the COVID‐19 pandemic, demand for blood products has remained high, while donations have declined. Institutional policies guiding the use of these products may affect their availability, utilisation and waste. We surveyed blood banks (BBs) in the United States (U.S.) to assess policies and practices related to cryoprecipitate ...
Chinelo P. Onyenekwu, Mariam Ratiani, Jenna Wade, Angela Treml   +3 more
wiley   +1 more source