Results 31 to 40 of about 78,600 (311)

Sex significantly influences transduction of murine liver by recombinant adeno-associated viral vectors through an androgen-dependent pathway. [PDF]

, 2003
A systematic evaluation of the influence of sex on transduction by recombinant adeno-associated viral vector (rAAV) indicated that transgene expression after liver-targeted delivery of vector particles was between 5- to 13-fold higher in male mice ...
Davidoff, AM, Nathwani, AC, Ng, CYC, Spence, Y, Zhou, J   +4 more
core   +1 more source

Spontaneous Iliopsoas Hematoma following Microvascular Free Tissue Transfer. [PDF]

, 2017
Spontaneous hematoma within the iliopsoas muscle (SIH) is a rare complication most commonly seen in coagulopathic patients. Often, patients undergoing microvascular free tissue transfer are anticoagulated for anastomotic patency.
Alemi, A Sean, Faden, Daniel L, Heaton, Chase M, Markey, Jeffrey D, Naunheim, Margaret L, Seth, Rahul   +5 more
core   +2 more sources

Study of musculoskeletal complications of hemophilia at a tertiary health-care center in Central India

Journal of Orthopaedic Diseases and Traumatology, 2019
Background: Hemophilia A, an X-linked recessive disorder of coagulation, caused due to the deficiency of coagulation factor-VIII and hemophilia-B caused due to the deficiency of factor-IX cause spontaneous and traumatic bleeding episodes, leading to ...
Sujeet Mishra, Deepak Maravi, Santosh Kumar Mishra, Suresh Uikey   +3 more
doaj   +1 more source

Bleeding Patterns among Severe Hemophilia A and B Patients in West Java

Althea Medical Journal, 2020
Background: The clinical manifestations of hemophilia A (HA) and hemophilia B (HB)are quite similar; however, the bleeding characteristics of these two hemophilia types have been reported to be different. This study aimed to explore the bleeding patterns
Muhammad Mufakkirul Islam, Susi Susanah, Amaylia Oehadian   +2 more
doaj   +1 more source

Chinese Expert Consensus on Pharmacokinetics Guided Treatment for Hemophilia A

罕见病研究, 2022
Hemophilia A is an X-chromosome-linked recessive genetic disease that lacks coagulation factor Ⅷ (Factor Ⅷ, FⅧ) and is clinically manifested as spontaneous or excessive bleeding after injury.The current main treatment for hemophilia A is alternative ...
Hemophilia Treatment Center Collaborative Network of China
doaj   +1 more source

Von Willebrand Disease [PDF]

, 2017
Von Willebrand Disease (VWD) is a blood clotting disorder characterized by low levels of the Von Willebrand Factor (VWF) in the blood. VWF is functions to bind platelets and promote clotting of the blood when vascular injury occurs.
Misla David, Ramon
core   +2 more sources

Haemophilia A: pharmacoeconomic review of prophylaxis treatment versus on-demand [PDF]

, 2015
Objectives. Haemophilia A is a congenital disorder of coagulation that mainly affects males and causes a considerable use of resources, especially when hemophilic patients are treated with prophylaxis.
BOCCIA, Antonio, LA TORRE, Giuseppe, Ricciardi, Walter, UNIM, BRIGID ANDOUNIMYE, Veneziano, Maria Assunta   +4 more
core   +2 more sources

Otogenic Sinus Thrombosis and Hemophilia: A Clinical Case

Кубанский научный медицинский вестник, 2023
Background. Patients with hemophilia are protected from thrombosis by a deficiency of one of coagulation factors, therefore thrombotic complications are rare in them.
I. M. Veshkurtseva, A. I. Izvin, N. E. Kuznetsova, S. A. Kudymov, A. Yu. Sinyakov, T. B. Kuznetsova   +5 more
doaj   +1 more source

Spontaneous spinal epidural hematoma in a known case of hemophilia a managed conservatively: A rare case report

Journal of Applied Hematology, 2021
Spontaneous spinal extradural hematomas are rarely attributed to hemophilia. When it occurs, magnetic resonance imaging (MRI) best establishes the diagnosis that should prompt immediate medical or surgical management.
Ashish Acharya, Ravindra Kumar Bind, Sarvpreet Singh Grewal, Paul Sudhakar John   +3 more
doaj   +1 more source

Clinical, instrumental, serological and histological findings suggest that hemophilia B may be less severe than hemophilia A

Haematologica, 2016
Recent evidence suggests that patients with severe hemophilia B may have a less severe disease compared to severe hemophilia A. To investigate clinical, radiological, laboratory and histological differences in the arthropathy of severe hemophilia A and ...
Daniela Melchiorre, Silvia Linari, Mirko Manetti, Eloisa Romano, Francesco Sofi, Marco Matucci-Cerinic, Christian Carulli, Massimo Innocenti, Lidia Ibba-Manneschi, Giancarlo Castaman   +9 more
doaj   +1 more source