Results 21 to 30 of about 118,583,499 (297)

Chinese Expert Consensus on Pharmacokinetics Guided Treatment for Hemophilia A

, 2022
Hemophilia A is an X-chromosome-linked recessive genetic disease that lacks coagulation factor Ⅷ (Factor Ⅷ, FⅧ) and is clinically manifested as spontaneous or excessive bleeding after injury.The current main treatment for hemophilia A is alternative ...
Hemophilia Treatment Center Collaborative Network of China
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New therapies for von Willebrand disease

Blood Advances, 2019
: The management of von Willebrand disease (VWD) is based upon the dual correction of the primary hemostasis defect, due to the inherited deficiency of von Willebrand factor (VWF), and of the secondary defect of factor VIII coagulant activity (FVIII:C ...
Pier Mannuccio Mannucci
doaj   +1 more source

Prophylaxis in Hemophilia

Clinical and Biomedical Research, 2023
Hemophilia is an inherited X-linked coagulopathy defined by a deficiency or abnormality in the clotting function of factor VIII (Hemophilia A) or factor IX (Hemophilia B).
Júlia Plentz Portich, Dayenne Catelli, Ebellins Tabares Calvache, Cristiane Seganfredo Weber, Daniel Sander Hoffmann, Guilherme Rasia Bosi, Leo Sekine, Lucia Mariano da Rocha Silla   +7 more
doaj  

Turoctocog alfa pegol (N8‐GP) in severe hemophilia A: Long‐term safety and efficacy in previously treated patients of all ages in the pathfinder8 study

Research and Practice in Thrombosis and Haemostasis, 2022
Background N8‐GP (turoctocog alfa pegol; Esperoct) is a glycoPEGylated human recombinant factor VIII (FVIII). Objectives Pathfinder8 (NCT01480180) was a phase 3, multinational, open‐label, nonrandomized trial to investigate the long‐term safety and ...
Steven R. Lentz, Kaan Kavakli, Robert Klamroth, Mudi Misgav, Azusa Nagao, Alberto Tosetto, Pernille Juul Jørgensen, Marek Zak, Laszlo Nemes   +8 more
doaj   +1 more source

Spontaneous bleeding in a patient with malignant lymphoma: A case of acquired hemophilia [PDF]

, 2000
Background: Acquired hemophilia is a rare condition which can be associated with lymphoproliferative disease. Case Report: Eleven yea rs after the diagnosis of immunocytoma had been made, a 72-year-old man developed a high-titer factor VIII inhibitor. At
Brack, N., Gesierich, Wolfgang, Pohlmann, H., Munker, Reinhold, Geiersberger, U., Hartenstein, R.   +5 more
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Hemophilia-related health problems reported in the PROBE questionnaire (N = 25).

, 2023
Hemophilia-related health problems reported in the PROBE questionnaire (N = 25).
Raul Gamarra (16503189), Juan-Sebastian Franco (649289), Liliana Torres (16503174), Maria del Rosario Forero (16503180), Diana Benavides (16503186), Oscar Peñuela (16503177), Marcela Rivera (12021472), Juan Satizabal (16503183), David Vizcaya (11520230), Ximena Salazar (11218570)   +9 more
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Hemophilia: a biography on therapeutical approaches

Clinical and Biomedical Research, 2023
The history of hemophilia is ancient, with descriptions dated to the 2nd century AD. The first modern narratives appeared in 1800s, when total blood transfusion was the only available treatment and life expectancy was remarkably low.
Dayenne Catelli, Júlia Plentz Portich, Ebellins Tabares Calvache, Cristiane Seganfredo Weber, Daniel Sander Hoffmann, Guilherme Rasia Bosi, Leo Sekine, Lucia Mariano da Rocha Silla   +7 more
doaj  

Hemophilia a genetic disorder: diagnosis, treatment and prognosis [PDF]

, 2016
Hemophilia a genetic disorder with patient’s inability to stop bleeding. There are two main types of hemophilia, hemophiliaA due to not enough clotting factor VIII and hemophilia B due to not enough factor IX,and acquired hemophilia A(AHA) caused by ...
AM Sharifa, Murtaza Mustafa, Ell. Illzam, Firdaus Mohd Hayati, Nornazirah Azizan, Ay Moktar   +5 more
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Cancers in patients with hemophilia: a retrospective study from the Italian Association of Hemophilia Centers.

, 2012
Summary. Background: The increased life expectancy of the hemophilia population, primarily as a result of advances in factor replacement therapy, has enabled hemophiliacs to reach an older age.
Macchi S, Giuffrida AC, Delios G, Coppola A, Castaman G, Arbasi M.C., SANTORO, Cristina, Scaraggi FA, Schinco P, Dragani A, Napolitano M, Santoro R, Morfini M, Lapecorella M, Tagliaferri A, Valdrè L, Di Perna C, Cantori I, MAZZUCCONI, Maria Gabriella, Pasca S, Serino ML, Rossetti G, Zanon E, Franchini M, Italian Association of Hemophilia Centers, Radossi P   +25 more
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Study of musculoskeletal complications of hemophilia at a tertiary health-care center in Central India

Journal of Orthopaedic Diseases and Traumatology, 2019
Background: Hemophilia A, an X-linked recessive disorder of coagulation, caused due to the deficiency of coagulation factor-VIII and hemophilia-B caused due to the deficiency of factor-IX cause spontaneous and traumatic bleeding episodes, leading to ...
Sujeet Mishra, Deepak Maravi, Santosh Kumar Mishra, Suresh Uikey   +3 more
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