Results 61 to 70 of about 82,032 (316)

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo, Roni Zemet, Allyson Nevins, Katherine Abraham, April D. Adams   +4 more
wiley   +1 more source

Sperm Sexing in Selected Animals and Humans: Methods, Applications, and Future Prospects

Andrology, EarlyView.
ABSTRACT Background Sperm sexing is a technique that enables the selection of offspring sex by sorting spermatozoa based on their sex chromosomes. This technology has gained increasing attention due to its potential applications in both animal breeding and human‐assisted reproduction.
Domrazek Kinga, Jurka Piotr
wiley   +1 more source

Supporting Children With a Chronic Disease and Their Parents When Admitted to Hospital: A Scoping Review of Psychosocial Supports

Acta Paediatrica, EarlyView.
Importance of psychosocial support. ABSTRACT Aim The aim of this scoping review was to identify, examine, and summarize available evidence regarding psychosocial supports provided to children with a chronic disease when admitted to hospital and their parents. Method The JBI methodology for conducting and reporting scoping reviews was followed.
Lyndsay Jerusha MacKay, Nolan Lagrisolal, Una Chang, Matthew Christoffersen, K. Alix Hayden, Kathryn Birnie, Tammie Dewan   +6 more
wiley   +1 more source

The association between unemployment and treatment among adults with hemophilia

Research and Practice in Thrombosis and Haemostasis
Background: People with hemophilia often experience pain and suffer from comorbidities related to their bleeding disorder. Consequently, unemployment due to disability is prevalent among people with hemophilia. Objectives: To explore associations between
Christian Qvigstad, Lars Q. Sørensen, Geir E. Tjønnfjord, Pål André Holme, Ingrid Pabinger, Cedric Hermans, Roseline d’Oiron, Robert Klamroth, Johannes Oldenburg, Natascha Marquardt, Peter Staritz, Olga Katsarou, Uri Martinowitz, Aharon Lubetsky, Gili Kenet, Annarita Tagliaferri, Maria Elisa Mancuso, Roger Schutgens, Pål André HolmE, Jerzy Windyga, Irena Zupan, Victor Jimenez Yuste, Ramiro Nunez, Philippe de Moerloose, Erik Berntorp, Jan Astermark, Campbell Tait, Gerry Dolan   +27 more
doaj   +1 more source

“Liver-related aspects of gene therapy for hemophilia: need for collaborations with hepatologists”: reply [PDF]

, 2023
Wolfgang Miesbach, Graham R. Foster, Flora Peyvandi   +2 more
openalex   +1 more source

Emergency department visits in children with hemophilia [PDF]

, 2012
Background The pediatric emergency department (ED) management of bleeding and other complications of hemophilia constitutes an increasingly important component of hemophilia therapy.
Callaghan, Michael U., Chitlur, Meera, Lusher, Jeanne M., Rajpurkar, Madhvi, Zia, Ayesha, Özgönenel, Bülent   +5 more
core   +1 more source

Human parvovirus B19 and blood product safety. A tale of twenty years of improvements [PDF]

, 2015
Parvovirus B19 (B19V), long known to be the causative agent of erythema infectiosum (fifth disease), is not a newly emerging agent. The aim of this review is to analyse the role played by this virus in compromising safety in transfusion medicine and the ...
Calizzani, Gabriele, Candura, Fabio, Facco, Giuseppina, Grazzini, Giuliano, Liumbruno, Giancarlo M., Marano, Giuseppe, Pupella, Simonetta, VAGLIO, Stefania   +7 more
core   +1 more source

Therapeutic potential of small molecules that block receptor‐induced Kv7/M‐current suppression in neuroprotection, seizures, and pain

British Journal of Pharmacology, EarlyView.
Receptor‐induced Kv7/M‐current suppression increases neuronal activity and contributes to pathology of several conditions. A new class of Kv7 modulators identified in this study attenuates M‐current suppression and shows therapeutic effects. Abstract Background and Purpose Neuronal Kv7 channels generate low voltage–gated potassium currents known as the
Young Woo Kim, Pavan Kumar Behara, Lamees Alhassen, Cindy Wong, Olivier Civelli, Naoto Hoshi   +5 more
wiley   +1 more source

Emicizumab in the treatment of hemophilia A [PDF]

Acta Stomatologica Naissi, 2020
Introduction: Despite substantial advances in the treatment of Hemophilia A with the use of concentrated factor VIII preparations during recent decades, bleeding episodes still occur from time to time.
Tijanić Ivan R., Golubović Ivana Z., Vučić Miodrag D., Tijanić Miloš R.   +3 more
doaj  

Garadacimab for the long‐term prophylaxis of hereditary angioedema

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Hereditary angioedema (HAE), a rare and debilitating disease characterized by recurrent and spontaneous attacks of tissue swelling, has a high unmet therapeutic need, with many patients experiencing insufficient disease control with current prophylactic treatments.
Emel Aygören‐Pürsün, Regina Treudler, Petra Staubach, Inmaculada Martinez Saguer, Thomas Linhoff, Markus Magerl   +5 more
wiley   +1 more source