Emicizumab in the treatment of hemophilia A [PDF]
Acta Stomatologica Naissi, 2020 Introduction: Despite substantial advances in the treatment of Hemophilia A with the use of concentrated factor VIII preparations during recent decades, bleeding episodes still occur from time to time.
Tijanić Ivan R. +3 more
doaj
INDUCTION OF TOLERANCE BY ORAL ADMINISTRATION OF FACTOR VIII AND TREATMENT OF HEMOPHILA [PDF]
, 2011 Disclosed herein is a simple method for the treatment of antigen-deficiency diseases, by orally administering to a Subject a therapeutically effective amount of the deficient anti gen, wherein the antigen is not present in a liposome.
Alpan, Oral +3 more
core +1 more source
Haemophilia A: pharmacoeconomic review of prophylaxis treatment versus on-demand [PDF]
, 2015 Objectives. Haemophilia A is a congenital disorder of coagulation that mainly affects males and causes a considerable use of resources, especially when hemophilic patients are treated with prophylaxis.
BOCCIA, Antonio +4 more
core +2 more sources
Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.Abstract Purpose Patello–femoral instability (PFI) is often caused by predisposing factors, with trochlea dysplasia (TD) as the most prominent. Untreated patellar instability leads to impaired function and an increased risk of patellofemoral osteoarthritis.
Christian Dippmann +4 more
wiley +1 more source
Spontaneous Retroperitoneal Hemorrhage Caused by Idiopathic Acquired Hemophilia A Misdiagnosed as a Delayed Traumatic Hematoma: A Case Report [PDF]
Journal of Acute Care Surgery, 2019 Acquired hemophilia A (AHA) is a rare disease where typically coagulation factor VIII is inhibited by autoantibodies. It occurs in patients with no personal or familial history of bleeding.
Seon Hee Kim +4 more
doaj +1 more source
Dynamical systems generated by a gonosomal evolution operator [PDF]
arXiv, 2015 In this paper we consider discrete-time dynamical systems generated by gonosomal evolution operators of sex linked inheritance. Mainly we study dynamical systems of a hemophilia, which biologically is a group of hereditary genetic disorders that impair the body's ability to control blood clotting or coagulation, which is used to stop bleeding when a ...
arxiv
Conditions for the difference set of a central Cantor set to be a Cantorval. Part II [PDF]
arXiv, 2023 Let C(a) be the central Cantor set generated by a sequence a with terms in (0,1). It is known that the difference set C(a)-C(a) of C(a) can has one of three possible forms: a finite union of closed intervals, a Cantor set, or a Cantorval. In the previous paper there was proved a sufficient condition for the sequence a which implies that C(a) - C(a) is ...
arxiv
Performance of AAV8 vectors expressing human factor IX from a hepatic-selective promoter following intravenous injection into rats [PDF]
, 2008 Background: Vectors based on adeno-associated virus-8 (AAV8) have shown efficiency and efficacy for liver-directed gene therapy protocols following intravascular injection, particularly in relation to haemophilia gene therapy. AAV8 has also been proposed
Baker, AH +4 more
core +2 more sources
Antithrombin: Deficiency, Diversity, and the Future of Diagnostics
Mass Spectrometry Reviews, EarlyView.ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt +2 more
wiley +1 more source
Hemophilia gene therapy knowledge and perceptions: Results of an international survey [PDF]
, 2020 Background Hemophilia gene therapy is a rapidly evolving therapeutic approach in which a number of programs are approaching clinical development completion. Objective The aim of this study was to evaluate knowledge and perceptions of a variety of health
A. Srivastava +8 more
core +1 more source