Results 81 to 90 of about 78,600 (311)

Physiological Aspects of Genetics [PDF]

, 1954
A considerable amount of evidence indicates that desoxyribonucleic acid is capable of duplicating itself, a property also possessed by genes. (By a self-duplicating material, we mean one which plays some essential role in its own production.) Watson ...
Horowitz, N. H., Owen, Ray D.
core   +1 more source

Outcomes and Healthcare Resource Utilisation in Adults With von Willebrand Disease Treated With Recombinant von Willebrand Factor in Surgical Settings in the United Kingdom

European Journal of Haematology, EarlyView.
ABSTRACT Objectives We describe treatment outcomes and healthcare resource utilisation (HCRU) in adults with von Willebrand disease (VWD) receiving recombinant von Willebrand factor (rVWF) in surgical settings in the United Kingdom. Methods Retrospective chart review of adults (≥ 18 years) with congenital VWD receiving first‐time rVWF for the ...
Mike Laffan, Heena Howitt, Cheryl Jones, Sarah Brighton, Rosa Willock, Anna Sanigorska, Oliver Heard   +6 more
wiley   +1 more source

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

European Principles of Nursing Care for Persons With Inherited Bleeding Disorders

Haemophilia, EarlyView.
ABSTRACT Introduction A nurse is one of the core members of the multidisciplinary haemophilia team. However, what people with inherited bleeding disorders (PwBD) can expect from them has not yet been formally defined. Aim This project, initiated by the EAHAD Nurses Committee, aimed to establish Principles of Nursing Care (PoNC) for PwBD to promote high‐
Nanda Uitslager, Mary Kavanagh, Maj Birkedal, Linda Myrin‐Westesson, the EAHAD Nurses Committee   +4 more
wiley   +1 more source

Navigating the Transition From Adolescence to Adulthood Among Young People With Severe Haemophilia: The Qualitative Phase of the TRANSHEMO Project

Haemophilia, EarlyView.
ABSTRACT Introduction Haemophilia causes spontaneous or prolonged bleeding due to a deficiency in clotting factor VIII (haemophilia A) or IX (haemophilia B). Although substitutive therapies and regular follow‐up can prevent severe haemorrhagic events, adherence to treatment remains a challenge.
Marie‐Anaïs Roques, Natacha Rosso‐Delsemme, Amandine Celli, Ngoc Anh Thu Nguyen, Martin Postzich, Sabine Castet, Yoann Huguenin, Annie Harroche, Anne Lienhart, Sandrine Meunier, Christine Biron‐Andréani, Florence Rousseau, Roseline d'Oiron, Yohann Repessé, Clémence Tabélé, Any Beltran Anzola, Thomas Sannié, Nicolas Giraud, Pascal Auquier, Hervé Chambost, Noémie Resseguier, The TRANSHEMO Study Group, Thémis Apostolidis, Laurent Ardillon, Karine Baumstarck, Sophie Bayart, Claire Berger, Marie‐Anne Bertrand, Carol Betsch, Annie Borel‐Derlon, Mohamed Boucekine, Thierry Calvez, Pierre Chamouni, Ségolène Claeyssens Donadel, Yannick Colle, Yesim Dargaud, Emmanuelle de Raucourt, Dominique Desprez, Céline Falaise, Alexandra Fournel, Birgit Frotscher, Valérie Gay, Fabienne Genre‐Volot, Jenny Goudemand, Yves Gruel, Benoît Guillet, Abel Hassoun, Audrey Hochart, Thierry Lambert, Aurélien Lebreton, Tanguy Leroy, Raphaël Marlu, Michèle Martin, Vanessa Milien, Fabrice Monpoux, Pierre Morange, Guillaume Mourey, Claude Negrier, Philippe Nguyen, Placide Nyombe, Caroline Oudot‐Challard, Brigitte Pan‐Petesch, Benoît Polack, Anne Rafowicz, Antoine Rauch, Delphine Rivaud, Pierre‐Simon Rohrlich, Pascale Schneider, Alexandra Spiegel, Cécile Stoven, Sophie Susen, Brigitte Tardy, Marc Trossaërt, Jean‐Baptiste Valentin, Stéphane Vanderbecken, Marie Viprey, Romain Voltzenlogel, Annelise Voyer‐Ebrard, Bénédicte Wibaut   +78 more
wiley   +1 more source

Nonneutralizing antibodies in Nordic persons with moderate hemophilia A and B (the MoHem study)

Research and Practice in Thrombosis and Haemostasis
Background: The impact of nonneutralizing antibodies (NNAs) in moderate hemophilia is elusive. Objectives: To explore the presence of NNAs in Nordic persons with moderate hemophilia A (MHA) and B (MHB) in relation to treatment modality, clinical outcome,
Ragnhild J. Måseide, MD, PhD, Erik Berntorp, MD, PhD, Jan Astermark, MD, PhD, Anna Olsson, MD, PhD, Maria Bruzelius, MD, PhD, Tony Frisk, MD, PhD, Vuokko Nummi, MD, PhD, Riitta Lassila, MD, PhD, Karin Strandberg, MD, PhD, Geir E. Tjønnfjord, MD, PhD, Pål A. Holme, MD, PhD   +10 more
doaj   +1 more source

Molecular Aggregation of Marketed Recombinant FVIII Products: Biochemical Evidence and Functional Effects

TH Open, 2019
Background Recombinant (rec-) coagulation factor VIII concentrates available for hemophilia A (HA) treatment differ in cell line production and structure, which could affect their pharmacodynamics and immunogenicity.
Raimondo De Cristofaro, Monica Sacco, Stefano Lancellotti, Federico Berruti, Isabella Garagiola, Carla Valsecchi, Maria Basso, Enrico Di Stasio, Flora Peyvandi   +8 more
doaj   +1 more source

Plasma Transfusions in Hemophilia [PDF]

, 1952
S. Van Creveld, M.M.P. Paulssen
openalex   +1 more source

Association of inferior vena cava filter placement for venous thromboembolic disease and a contraindication to anticoagulation with 30-day mortality [PDF]

, 2018
Importance: Despite the absence of data from randomized clinical trials, professional societies recommend inferior vena cava (IVC) filters for patients with venous thromboembolic disease (VTE) and a contraindication to anticoagulation therapy.
Brown, David L, Novak, Eric, Saeed, Mohammed J, Turner, Tyson E   +3 more
core   +1 more source

European Management of Glanzmann's Thrombasthenia: A Survey of Current Clinical Practice

Haemophilia, EarlyView.
ABSTRACT Introduction Glanzmann's thrombasthenia is a rare inherited platelet disorder characterized by a lack of platelet aggregation. Patients tend to be diagnosed in early childhood with treatment strategies involving a multifaceted approach to prevent and manage bleeding episodes.
Mathieu Fiore, Andrea Artoni, Robert Klamroth, Mary Mathias, Roger Schutgens, Roseline d'Oiron, EAHAD Glanzmann Thrombasthenia Working Group   +6 more
wiley   +1 more source