Results 91 to 100 of about 13,301,732 (374)

Multiple Comorbid Conditions among Middle-Aged and Elderly Hemophilia Patients: Prevalence Estimates and Implications for Future Care [PDF]

open access: yes, 2011
Introduction. Advances in hemophilia care and treatment have led to increases in the life expectancy among hemophiliacs. As a result, persons with hemophilia are reaching an older age and experiencing various age-related health conditions never seen ...
Brown, Deborah   +3 more
core   +3 more sources

A new era for hemophilia B treatment [PDF]

open access: yesBlood, 2016
In this issue of Blood, Santagostino et al, in their phase 3 study, demonstrate efficacy and safety of recombinant fusion protein linking coagulation factor IX (FIX) with albumin (rIX-FP) which, along with the other 2 extended half-life FIX products, heralds a new era for the treatment of hemophilia B.
Rebecca Kruse-Jarres, Jason A. Taylor
openaire   +3 more sources

Could PTH/Ca Ratio Serve as a New Marker for Evaluating Bone Metabolism in Hemophilia Patients?

open access: yesDiagnostics
Background/Objectives: Low bone mineral density (BMD) is common in hemophilia patients. Identifying high-risk patients for low BMD early is essential to prevent complications and reduce morbidity.
Tuba Ersal   +8 more
doaj   +1 more source

Difficulties in the treatment of an Infant with Hemophilia B [PDF]

open access: yesTürk Pediatri Arşivi, 2016
Dear Editor, Hemophilia B is a X-linked recessive bleeding disorder which occurs as a result of Factor IX (FIX) deficiency (1, 2). In some patients with hemophilia, antibody (inhibitor) and allergic reaction may develop against FIX protein which is administered for treatment (3).
Zulfikar, Bulent   +3 more
openaire   +4 more sources

Investigating the role of SARM1 in central nervous system

open access: yesIbrain, EarlyView.
Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang   +4 more
wiley   +1 more source

Fractional Populations in Sex-linked Inheritance [PDF]

open access: yesarXiv, 1998
We study the fractional populations in chromosome inherited diseases. The governing equations for the fractional populations are found and solved in the presence of mutation and selection. The physical fixed points obtained are used to discuss the cases of color blindness and hemophilia.
arxiv  

Queen Victoria and The Royal Disease [PDF]

open access: yes, 2018
Queen Victoria, Queen of England and Ireland and Empress of India, is the second longest ruling monarch of England, she sat on the throne for sixty –three years and was so crucial to the formation of England that there is a whole era names after her, The
Mullen, Madeline
core   +1 more source

Efanesoctocog Alfa Population Pharmacokinetics and Repeated Time‐To‐Event Analysis of Bleeds in Adults, Adolescents, and Children with Severe Hemophilia A

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Efanesoctocog alfa is a first‐in‐class high‐sustained factor VIII (HSF) replacement therapy for treatment of hemophilia A. This article presents population pharmacokinetics (PopPK) of efanesoctocog alfa and repeated time‐to‐event (RTTE) analysis of bleeding episodes in adults/adolescents (≥12 years of age) and children (<12 years).
Nancy Wong   +7 more
wiley   +1 more source

Christmas Disease (Hemophilia –B) – A Case Report

open access: yesBangabandhu Sheikh Mujib Medical University Journal, 2010
We report a 25 years old man developed Haemarthrosis of left hip joint with a history of recurrent swelling and pain in multiple joints and prolonged bleeding following minor trauma since childhood.
Md Rafiqul Alam   +5 more
doaj   +1 more source

Dynamical systems generated by a gonosomal evolution operator [PDF]

open access: yesarXiv, 2015
In this paper we consider discrete-time dynamical systems generated by gonosomal evolution operators of sex linked inheritance. Mainly we study dynamical systems of a hemophilia, which biologically is a group of hereditary genetic disorders that impair the body's ability to control blood clotting or coagulation, which is used to stop bleeding when a ...
arxiv  

Home - About - Disclaimer - Privacy