Results 111 to 120 of about 49,324 (252)

Outcomes of Emicizumab Treatment for Haemophilia A Paediatric Patients: A Systematic Review With Meta‐Analysis

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Haemophilia A in paediatric patients presents a lifelong risk of spontaneous and trauma‐induced haemorrhage, leading to progressive joint damage, disability and impaired quality of life. Emicizumab, a bispecific monoclonal antibody administered subcutaneously, offers sustained haemostatic protection and has shown promising ...
Konstantina Bolou   +6 more
wiley   +1 more source

Prophylaxis in Hemophilia

open access: yesClinical and Biomedical Research, 2023
Hemophilia is an inherited X-linked coagulopathy defined by a deficiency or abnormality in the clotting function of factor VIII (Hemophilia A) or factor IX (Hemophilia B).
Júlia Plentz Portich   +7 more
doaj  

Maximum Likelihood Estimation of the Multivariate Normal Mixture Model [PDF]

open access: yes
The Hessian of the multivariate normal mixture model is derived, and estimators of the information matrix are obtained, thus enabling consistent estimation of all parameters and their precisions.
Boldea, Otilia, Magnus, Jan R.
core   +1 more source

TREATMENT OF HEMOPHILIA WITH HUMAN FACTORIX PRODUCED IN MAMIMARY TISSUE OF TRANSGENIC MAMMALS [PDF]

open access: yes, 2008
Recombinant Factor IX characterized by a high percentage of active protein can be obtained in the milk of transgenic animals that incorporate chimeric DNA molecules according to the present invention.
Drohan, William N.   +4 more
core   +1 more source

Guidelines for management of hemophilia A and B [letter; comment] [PDF]

open access: bronze, 1995
Benjamin Djulbegović, G. Goldsmith
openalex   +1 more source

The Trust‐Link Relational Transition Model: A Unitary Caring Framework for Youth With HIV Transitioning to Adult Healthcare

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims To develop a conceptual model integrating Robinson's Theory of Trust and Watson's Caritas Processes to guide trust‐building approaches and caring practices that support adolescents and young adults with HIV during the healthcare transition from paediatric to adult care.
Emily Anne Barr, Sara Horton‐Deutsch
wiley   +1 more source

ORAL TREATMENT OF HEMOPHILIA [PDF]

open access: yes, 2007
Disclosed herein is a simple method for the treatment of antigen-deficiency diseases, by orally administering to a subject a therapeutically effective amount of the deficient antigen, wherein the antigen is not present in a liposome.
Alpan, Oral   +3 more
core   +1 more source

Multinational transfusion practices and outcomes in haematology patients admitted to the intensive care unit

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives The number of critically ill patients with haematological conditions is increasing, yet transfusion practices in this population remain poorly defined. This study aimed to compare transfusion strategies in critically ill patients with versus without haematological conditions.
Caroline M. Schaap   +288 more
wiley   +1 more source

Hemophilia B: Genetic Variants and Carrier Detection [PDF]

open access: hybrid, 1977
Carol K. Kasper   +2 more
openalex   +1 more source

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