Results 121 to 130 of about 301,643 (264)

E-theory is a special case of KK-theory [PDF]

arXiv, 2002
Let A and B be $C^*$-algebras, A separable, and B $\sigma$-unital and stable. It is shown that there are natural isomorphisms $E(A,B)=KK(SA,Q(B))=[SA,Q(B)\otimes K]$, where $SA=C_0(0,1)\otimes A$, $[\cdot,\cdot]$ denotes the set of homotopy classes of *-homomorphisms, $Q(B) = M(B)/B$ is the generalized Calkin algebra and K denotes the $C^*$-algebra of ...
arxiv  

Molecular basis of hemophilia B: a defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursor. [PDF]

, 1986
David Diuguid, Marie‐Josèphe Rabiet, Bruce Furie, Howard A. Liebman, Bruce Furie   +4 more
openalex   +1 more source

Chromatography in Downstream Processing of Recombinant Adeno‐Associated Viruses: A Review of Current and Future Practises

Biotechnology and Bioengineering, Volume 122, Issue 5, Page 1067-1086, May 2025.
ABSTRACT Recombinant adeno‐associated virus (rAAV) has emerged as an attractive gene delivery vector platform to treat both rare and pervasive diseases. With more and more rAAV‐based therapies entering late‐stage clinical trials and commercialization, there is an increasing pressure on the rAAV manufacturing process to accelerate drug development ...
Julius Klemens Lorek, Madelène Isaksson, Bernt Nilsson   +2 more
wiley   +1 more source

Hemophilia B in a male with a four-base insertion that arose in the germline of his mother [PDF]

, 1989
C. D. K. Bottema, Rhett P. Ketterling, H.I. Cho, Steve S. Sommer   +3 more
openalex   +1 more source

A Toolkit for Healthcare Transition for Adolescents With Classical Myeloproliferative Neoplasms

Pediatric Blood &Cancer, Volume 72, Issue 5, May 2025.
ABSTRACT Classical myeloproliferative neoplasms (MPNs) are being identified more frequently in adolescents. There is no guidance on the healthcare transition of young MPN patients from pediatric to adult medicine. Therefore, we convened an international panel of experts in both pediatric and adult MPN care to develop three tools to facilitate high ...
Nicole Kucine, Holger Cario, Ghaith Abu‐Zeinah, Maria Caterina Putti, Nicolas Boissel, Maria Luigi Randi, Linda Resar, Martin Griesshammer, Jean‐Jacques Kiladjian   +8 more
wiley   +1 more source

Clinical audit of inherited bleeding disorders in a developing country

Indian Journal of Pathology and Microbiology, 2010
Objective: We did a clinical audit to determine the status of coagulation disorders in a hemophilia care center in Pakistan. Setting: Fatimid foundation blood bank and hematological diseases center, Lahore.
Sajid Raihan, Khalid Safoorah, Mazari Nazish, Azhar Waleed, Khurshid Mohammad   +4 more
doaj  

A Dutch family with moderately severe hemophilia B (Factor IX_Heerde) has a missense mutation identical to that of factor lX_{London 2} [PDF]

, 1989
S R Poort, E Briët, R M Bertina, P H Reitsma   +3 more
openalex   +1 more source

Behavioral Abnormalities, Cognitive Impairments, Synaptic Deficits, and Gene Replacement Therapy in a CRISPR Engineered Rat Model of 5p15.2 Deletion Associated With Cri du Chat Syndrome

Advanced Science, Volume 12, Issue 14, April 10, 2025.
A new CdCS rat model is developed using CRISPR‐Cas9 technology. It shows impairments in cognitive and social behaviors, neuronal dendrite abnormalities in the hippocampus and mPFC, and inflammatory and immune processes in mPFC brain cells. Early AAV‐Ctnnd2 gene therapy enhances cognitive function in CdCS rats.
Jingjing Shen, Yan Wang, Yang Liu, Junying Lan, Shuang Long, Yingbo Li, Di Chen, Peng Yu, Jing Zhao, Yongjun Wang, Shali Wang, Feng Yang   +11 more
wiley   +1 more source

Treatment of hemophilia B: focus on recombinant factor IX

Biologics: Targets & Therapy, 2013
Massimo Franchini, Francesco Frattini, Silvia Crestani, Cinzia Sissa, Carlo BonfantiDepartment of Transfusion Medicine and Hematology, Carlo Poma Hospital, Mantua, ItalyAbstract: Hemophilia B is a recessive X-linked bleeding disorder characterized by ...
Franchini M, Frattini F, Crestani S, Sissa C, Bonfanti C   +4 more
doaj  

Splice junction mutations in factor IX gene resulting in severe hemophilia B [PDF]

, 1991
S.H. Chen, Miqin Zhang, Arthur R. Thompson, Gordon L. Bray, C. Ronald Scott   +4 more
openalex   +1 more source