Results 151 to 160 of about 13,086,034 (342)
Journal of Advanced Nursing, EarlyView.ABSTRACT Aims To develop a conceptual model integrating Robinson's Theory of Trust and Watson's Caritas Processes to guide trust‐building approaches and caring practices that support adolescents and young adults with HIV during the healthcare transition from paediatric to adult care.
Emily Anne Barr, Sara Horton‐Deutsch
wiley +1 more source
MOLECULAR BASIS OF HEMOPHILIA B: IDENTIFICATION OF THE DEFECT IN FACTOR IX VANCOUVER [PDF]
, 1987 V A Geddes +3 more
openalex +1 more source
Maximum Likelihood Estimation of the Multivariate Normal Mixture Model [PDF]
The Hessian of the multivariate normal mixture model is derived, and estimators of the information matrix are obtained, thus enabling consistent estimation of all parameters and their precisions.
Boldea, Otilia, Magnus, Jan R.
core +1 more source
Characterization and management of patients with hereditary factor X deficiency: A case series
Transfusion, EarlyView.Abstract Background Hereditary factor X deficiency (HFXD) is an ultra‐rare, autosomal recessive bleeding disorder that results in reduced factor X coagulant activity (FX:C). HFXD is traditionally classified by severity as severe (FX:C <1%), moderate (FX:C = 1%–5%), or mild (FX:C = 6%–10%).
Meera Chitlur +4 more
wiley +1 more source
Hemophilia B with inhibitor: molecular analysis of the subtotal deletion of the factor IX gene [PDF]
, 1985 H. J. Hassan +8 more
openalex +1 more source
TREATMENT OF HEMOPHILIA WITH HUMAN FACTORIX PRODUCED IN MAMIMARY TISSUE OF TRANSGENIC MAMMALS [PDF]
, 2008 Recombinant Factor IX characterized by a high percentage of active protein can be obtained in the milk of transgenic animals that incorporate chimeric DNA molecules according to the present invention.
Drohan, William N. +4 more
core +1 more source
Biotechnology and Bioengineering, Volume 122, Issue 11, Page 3051-3060, November 2025.Accelerated, quality‐by‐design‐driven development and scale‐up of recombinant AAV production, from high‐throughput bench scale to commercial scale. ABSTRACT Adeno‐associated virus (AAV) is one of the most common delivery systems used in gene therapy.
Angela Andaluz +6 more
wiley +1 more source
ORAL TREATMENT OF HEMOPHILIA [PDF]
, 2007 Disclosed herein is a simple method for the treatment of antigen-deficiency diseases, by orally administering to a subject a therapeutically effective amount of the deficient antigen, wherein the antigen is not present in a liposome.
Alpan, Oral +3 more
core +1 more source
Journal of Inherited Metabolic Disease, Volume 48, Issue 6, November 2025.ABSTRACT Liver transplantation (LTx) has become, over the years, an increasingly used therapeutic option in patients with inherited metabolic diseases (IMD). Initially performed for Tyrosinemia Type I and ornithine transcarbamylase deficiency, it now accounts as the second indication for pediatric transplants worldwide. The use of LTx has been extended
Andrea Pietrobattista +3 more
wiley +1 more source
Use of a BamHI polymorphism in the factor IX gene for the determination of hemophilia B carrier status [PDF]
, 1986 CW Hay +5 more
openalex +1 more source