Results 161 to 170 of about 50,045 (313)

Interfacility Collaboration for Hemophilia Care in Japan: A Retrospective Database Study Using a Japanese Healthcare Claims Database

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims In Japan, about 6000 patients with hemophilia A (PwHA) are separately cared for at ~1000 clinics or hospitals. Interfacility collaboration (IFC) between hemophilia treatment centers and “satellite” medical facilities located closer to patients is necessary to eliminate care disparities.
Ei Kinai, Masako Yamaguchi, Akira Shirahata   +2 more
wiley   +1 more source

Rebalancing Hemostasis: Fitusiran as a First‐in‐Class RNAi Therapy in Hemophilia A and B

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Fitusiran is a first‐in‐class RNA interference (RNAi) therapy that lowers antithrombin (AT) to rebalance hemostasis in people with Hemophilia A or B, with or without inhibitors. Its recent FDA approval marks a major shift toward factor‐independent prophylaxis.
Raza Ur Rehman, Rida Fatima, Aymar Akilimali   +2 more
wiley   +1 more source

Evaluation of coagulation disorders and iron deficiency in women with heavy menstrual bleeding

International Journal of Gynecology &Obstetrics, Volume 172, Issue 1, Page 250-254, January 2026.
Abstract Objective To explore the incidence of congenital bleeding disorders (CBD), which may result in anemia, in a large cohort of women referred for heavy menstrual bleeding (HMB) in a specialized gynecologic unit. Methods Between January 2022 and January 2024, all women referred for HMB were screened.
Lucia Rugeri, Yelena Fruchou, Caroline Brodbeck, Marianne Bastien, Amandine Lioux, Giulia Gouy, Marion Cortet, Gil Dubernard, Yesim Dargaud   +8 more
wiley   +1 more source

Somatic mosaicism and female-to-female transmission in a kindred with hemophilia B (factor IX deficiency).

, 1991
Scott A. Taylor, Ken V. Deugau, D Lillicrap   +2 more
openalex   +2 more sources

Balancing Promise and Peril: Hemophilia Gene Therapy Insights

IUBMB Life, Volume 78, Issue 1, January 2026.
ABSTRACT Hemophilia is an inherited disorder characterized by impaired blood clotting caused by mutations in the genes responsible for producing coagulation factor (F) VIII (hemophilia A, HA) or FIX (hemophilia B, HB). Current treatment primarily relies on replacement therapy, involving frequent and costly infusions of FVIII or FIX concentrates.
Saicharan Akula, Ester Borroni, Alessia Cottonaro, Antonia Follenzi, Simone Merlin   +4 more
wiley   +1 more source

625. Nonviral Gene Transfer of a Plasmid Encoding a B Domain Variant FVIII/N6 cDNA Reduced Inhibitory Anti-FVIII Antibody Titer in Hemophilia A Mice [PDF]

, 2009

openalex   +1 more source

Remarkable Prolongation of Irreversible APTT and Non‐Significant Hemorrhage: A Rare High Titer of FVIII Inhibitor Case Report and Literature Review

Journal of Clinical Laboratory Analysis, Volume 40, Issue 2, January 2026.
Patient with a bladder cancer history presented was diagnosed with Acquired hemophilia A (AHA) according to imaging findings and laboratory tests. The parameters returned to normal after treatment of methylprednisolone and cyclophosphamide. With the recurrence of AHA, the patient was finally confirmed to have liver metastases.
Ke‐Han Zhang, Song‐Song Lu, Pei‐Liang Gao, Xue‐Ying Fu, Gui‐Ying Dong   +4 more
wiley   +1 more source

The Template-Jumping Editing Approach in <i>F9</i>-Associated Hemophilia B Gene Therapy. [PDF]

Int J Mol Sci
Sattarov R, Kuznetsov A, Klimko V, Ignatyeva E, Ivanov R, Karabelsky A, Fizikova A.   +6 more
europepmc   +1 more source

Intra‐articular and intra‐osseous expanded adipose‐derived stromal cell injections for knee osteoarthritis‐related bone marrow lesions yield promising outcomes: Preliminary results in 16 athletes

Journal of Experimental Orthopaedics, Volume 13, Issue 1, January 2026.
Abstract Purpose To explore the results of a fluoroscopic‐guided intra‐osseous (IO) and intra‐articular (IA) injection of expanded adipose‐derived stromal cells (ASCs) in athletes with bone marrow lesions (BML) associated with knee osteoarthritis (OA).
Miguel A. Khoury, Emmanuel T. Papakostas, Theodorakys Marín Fermín, Montassar Tabben, Karim Chamari, Lorena Levi, Khaled Alkhelaifi, Pieter D'Hooghe   +7 more
wiley   +1 more source

Left Atrial Appendage Closure in a Hemophilia B Patient with Atrial Fibrillation. [PDF]

Anatol J Cardiol
Özbebek YE, Ertem AG.
europepmc   +1 more source