Neurodevelopmental disorder-causing GRIN1 Y647S variant alters red blood cell physiology in mice. [PDF]
Genetically‐modified mice with the Y647S substitution were used to study blood physiology and identify potential biomarkers for GRIN disorder patient stratification. Red blood cells from these mice have increased NMDA receptor mediated calcium influx, indicating a gain‐of‐function phenotype.
Okafor SC +13 more
europepmc +2 more sources
Exploring Patterns of Dynamic Size Changes of Lesions after Hepatic Microwave Ablation in an In Vivo Porcine Model [PDF]
Microwave ablation (MWA) is a type of minimally invasive cancer therapy that uses heat to induce necrosis in solid tumours. Inter- and post-ablational size changes can influence the accuracy of control imaging, posing a risk of incomplete ablation.
Bressem, Keno K. +8 more
core +1 more source
Hemorheological Parameters in Diabetic Patients: Role of Glucose Lowering Therapies
Diabetes mellitus influences several important hemorheological parameters including blood viscosity, erythrocyte aggregation and deformability. In the present study, 159 type-2 diabetic patients and 25 healthy controls were involved.
Katalin Biro +5 more
doaj +1 more source
Comparative data on blood composition and blood flow properties indicate different levels of interspecies variation for several parameters. Hematocrit and hemoglobin levels have relatively low variability among mammals, while mean cell volume and red blood cell (RBC) count are more variable.
Oguz K, Baskurt, Herbert J, Meiselman
openaire +5 more sources
An overview about erythrocyte membrane [PDF]
© 2010 – IOS Press and the authors. All rights reservedIn the sixties and seventies, erythrocytes or red blood cells (RBCs) were extensively studied. Much has been learnt particularly concerning their metabolism and gas transporter function. In the past
Oliveira, Sofia de, Saldanha, Carlota
core +1 more source
Acute normoxic exercise impacts the rheological properties of red blood cells (RBC) and their senescence state; however, there is a lack of data on the effects of exercise performed in hypoxia on RBC properties.
Romain Carin +11 more
doaj +1 more source
Evidence that the degree of band 3 phosphorylation modulates human erythrocytes nitric oxide efflux – in vitro model of hyperfibrinogenemia [PDF]
© 2011 – IOS Press and the authors. All rights reservedRecent evidence has shown that plasma fibrinogen, a major cardiovascular risk factor, interacts with the erythrocyte membrane and acts to influence blood flow via erythrocyte nitric oxide (NO ...
Almeida, J. P. Lopes de +2 more
core +1 more source
Context Ginkgo biloba Linn (Ginkgoaceae) [leaves extract (GBE)] is authorized for the treatment of sudden hearing loss (SHL); however, its clinical feasibility in SHL has not been thoroughly investigated.Objective To evaluate the efficacy and safety of ...
Chao Yuan +3 more
doaj +1 more source
Studying the cutaneous microcirculatory response during upper-limb exercise in healthy, older, sedentary people [PDF]
This study investigated changes incurred in cutaneous skin blood flux (SKBF) in the superficial veins of the lower limb by upper limb exercise training in the form of arm-cranking in 14 healthy participants over the age of 50 years. Changes in cutaneous
Klonizakis, Markos
core +1 more source
Improved Visualization of the Necrotic Zone after Microwave Ablation Using Computed Tomography Volume Perfusion in an In Vivo Porcine Model [PDF]
After hepatic microwave ablation, the differentiation between fully necrotic and persistent vital tissue through contrast enhanced CT remains a clinical challenge.
Bressem, Keno K. +8 more
core +1 more source

