Results 141 to 150 of about 594,429 (316)
Advanced Science, EarlyView.Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang +13 more
wiley +1 more source
Advanced Science, EarlyView.By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao +11 more
wiley +1 more source
Management of intracerebral hemorrhage
, 2007 Ramandeep Sahni, Jesse WeinbergerDepartment of Neurology, Mount Sinai School of Medicine, New York, NY, USAAbstract: Currently, intracerebral hemorrhage (ICH) has the highest mortality rate of all stroke subtypes (Counsell et al 1995; Qureshi et al 2005).
Ramandeep Sahni, Jesse Weinberger
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Advanced Science, EarlyView.This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang +12 more
wiley +1 more source
Management of hemorrhage in gastrointestinal stromal tumors: a review
, 2018 Qi Liu,1 Fanmin Kong,1 Jianping Zhou,1 Ming Dong,1 Qi Dong2 1Department of Gastrointestinal Surgery, The First Hospital, China Medical University, Shenyang, China; 2Department of General Surgery, The People’s Hospital, China Medical University ...
Kong F, Dong M, Liu Q, Dong Q, Zhou J
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PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
Advanced Science, EarlyView.This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source
Etiology and management of nasopharyngeal hemorrhage after radiotherapy for nasopharyngeal carcinoma
, 2019 Jiabin Zhan,1,* Shuai Zhang,2,* Xin Wei,1 Yihui Fu,3 Jing Zheng1 1Department of Otolaryngology, Hainan General Hospital, Haikou 570311, Hainan, China; 2Department of Radiation Oncology, Hainan General Hospital, Haikou 570311, Hainan Province, China ...
Zheng J, Fu Y, Wei X, Zhang S, Zhan J
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Solid Harmonic Wavelet Bispectrum for Image Analysis
Advanced Science, EarlyView.The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown +3 more
wiley +1 more source
, 2015 Kamyar Vaziri,1 Stephen G Schwartz,1 Krishna S Kishor,1 Jorge A Fortun,1 Darius M Moshfeghi,2 Andrew A Moshfeghi,3 Harry W Flynn Jr1 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA;
Vaziri K +6 more
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Advanced Science, EarlyView.ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung +19 more
wiley +1 more source