Identification of erythroferrone as an erythroid regulator of iron metabolism. [PDF]
Recovery from blood loss requires a greatly enhanced supply of iron to support expanded erythropoiesis. After hemorrhage, suppression of the iron-regulatory hormone hepcidin allows increased iron absorption and mobilization from stores.
Ganz, Tomas +5 more
core +1 more source
Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]
Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Arai, Ken +13 more
core +3 more sources
A ruptured vulvar labial artery pseudoaneurysm causes a secondary postpartum hemorrhage: A case report. [PDF]
Background:Postpartum hemorrhage is the most common cause of maternal morbidity in the United States. However, secondary postpartum hemorrhage is rare and includes pseudoaneurysms, which represent only 3.3% of all cases of secondary postpartum hemorrhage.
Lane, Felicia +3 more
core
Minimal long-term neurobehavioral impairments after endovascular perforation subarachnoid hemorrhage in mice [PDF]
Cognitive deficits are among the most severe and pervasive consequences of aneurysmal subarachnoid hemorrhage (SAH). A critical step in developing therapies targeting such outcomes is the characterization of experimentally-tractable pre-clinical models ...
Brody, David L +5 more
core +2 more sources
Relationship of blood pressure, antihypertensive therapy, and outcome in ischemic stroke treated with intravenous thrombolysis: retrospective analysis from Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR) [PDF]
<p><b>Background and Purpose:</b> The optimal management of blood pressure (BP) in acute stroke remains unclear. For ischemic stroke treated with intravenous thrombolysis, current guidelines suggest pharmacological intervention if ...
Ahmed, N. +4 more
core +1 more source
IntroductionClazosentan, a selective endothelin receptor subtype A antagonist, reduces vasospasm-related morbidity and all-cause mortality following aneurysmal subarachnoid hemorrhage (SAH) in the Japanese population, as demonstrated by a recent ...
Hiroyuki Sakata +15 more
doaj +1 more source
Secondary Hematoma Expansion and Perihemorrhagic Edema after Intracerebral Hemorrhage: From Bench Work to Practical Aspects. [PDF]
Intracerebral hemorrhages (ICH) represent about 10-15% of all strokes per year in the United States alone. Key variables influencing the long-term outcome after ICH are hematoma size and growth.
Lim-Hing, Krista, Rincon, Fred
core +2 more sources
: There are no reported estimates of normal or abnormal bleeding in dogs during the hemilaminectomy and intervertebral disc fenestration procedures (HF), and that makes it difficult to study intraoperative complications, hemostasis methods, and the ...
Dênis Antonio Ferrarin +7 more
doaj +1 more source
Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT trial [PDF]
<p><b>Background and Purpose:</b> NXY-059 is a free radical-trapping neuroprotectant developed for use in acute ischemic stroke. To facilitate prompt administration of treatment, potentially before neuroimaging, we investigated the ...
Ahlberg, G. +12 more
core +1 more source
Primary hyperfibrinolysis as the presenting sign of prostate cancer: A case report [PDF]
Introduction. A bleeding syndrome in the setting of primary hyperfibrinolysis in a prostate cancer patient is only 0.40– 1.65% of cases. The laboratory diagnosis of primary hyperfibrinolysis is based on the increase of biomarkers like D-dimer, fibrinogen
Kulić Andrijana +2 more
doaj +1 more source

